Haemophilus parainfluenzae: report of an unusual cause of neonatal sepsis and a literature review.

Haemphilus parainfluenzae, an unusual cause of early-onset neonatal sepsis, is rarely reported. Risk factors for this serious infection include prolonged rupture of membranes, choriamnionitis, and prematurity. A high index of suspicion, proper culture techniques, and rapid species identification are needed to diagnose H. parainfluenzae sepsis. We present the first documented case from India with a review of the literature.

[1]  R. Humphries,et al.  Establishing diagnosis of Haemophilus parainfluenzae as etiology of culture-negative endocarditis using DNA sequence analysis on tissue specimen. , 2011, American Journal of Medicine.

[2]  N. Kennea,et al.  Neonatal infections in England: the NeonIN surveillance network , 2010, Archives of Disease in Childhood: Fetal and Neonatal Edition.

[3]  A. Daley,et al.  Invasive Haemophilus parainfluenzae maternal–infant infections: An Australasian perspective and case report , 2006, Australian and New Zealand journal of obstetrics and gynaecology.

[4]  J. Bradley,et al.  Haemophilus parainfluenzae Sepsis in a Very Low Birth Weight Premature Infant: A Case Report and Review of the Literature , 1999, Journal of Perinatology.

[5]  M. Tilse,et al.  Biotypes of Haemophilus influenzae that are associated with noninvasive infections , 1991, Journal of clinical microbiology.

[6]  J. Musser,et al.  Typing of urogenital, maternal, and neonatal isolates of Haemophilus influenzae and Haemophilus parainfluenzae in correlation with clinical source of isolation and evidence for a genital specificity of H. influenzae biotype IV , 1989, Journal of clinical microbiology.

[7]  Grosfeld Jl,et al.  Haemophilus parainfluenzae Infections in Children, with the Report of a Unique Case , 1988 .

[8]  E. Bell,et al.  Fulminant neonatal septicemia due to Hemophilus parainfluenzae. , 1984, American journal of clinical pathology.

[9]  Washington Ja nd,et al.  Vaginal flora in asymptomatic women. , 1976 .

[10]  A. Daly,et al.  Puerperal bacteremia and neonatal sepsis due to Hemophilus parainfluenzae: report of a case with antibody titers. , 1972, Pediatrics.

[11]  E. Gullekson,et al.  Haemophilus parainfluenzae meningitis in a newborn. , 1966, JAMA.

[12]  J. Grosfeld,et al.  Haemophilus parainfluenzae infections in children, with the report of a unique case. , 1988, Reviews of infectious diseases.

[13]  J. Washington,et al.  Vaginal flora in asymptomatic women. , 1976, Mayo Clinic proceedings.

[14]  J. Washington,et al.  Three Hemophilus species. Pathogenic activity. , 1971, American journal of diseases of children.