Deterministic center of pressure patterns characterize postural instability in Parkinson’s disease

Static posturographic recordings were obtained from six Parkinson’s patients and six age-matched, healthy control participants. The availability of vision and visuo-spatial cognitive load were manipulated. Postural sway patterns were analyzed using recurrence quantification analysis (RQA), which revealed differences in center of pressure (COP) dynamics between Parkinson’s and control participants. AP COP trajectories for the Parkinson’s group were not only significantly more variable than for the control group, but also exhibited distinct patterns of temporal dynamics. The visual manipulation did not differentially affect the two groups. No cognitive load effects were found. The results are generally consistent with the hypothesis that pathological physiological systems exhibit a tendency for less flexible, more deterministic dynamic patterns.

[1]  B. Djahanguiri,et al.  The prevention of acute gastric ulcer in the rat by alpha-methyldopa. , 1967, Medicina et pharmacologia experimentalis. International journal of experimental medicine.

[2]  M. Hoehn,et al.  Parkinsonism , 1967, Neurology.

[3]  R. Shepard,et al.  Mental Rotation of Three-Dimensional Objects , 1971, Science.

[4]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[5]  G. Powell,et al.  Power spectral density analysis of lateral human standing sway. , 1984, Journal of motor behavior.

[6]  D. Ruelle,et al.  Recurrence Plots of Dynamical Systems , 1987 .

[7]  A. Shumway-cook,et al.  Postural sway biofeedback: its effect on reestablishing stance stability in hemiplegic patients. , 1988, Archives of physical medicine and rehabilitation.

[8]  W. Koller,et al.  Falls and Parkinson's disease. , 1989, Clinical neuropharmacology.

[9]  Michael G. Akritas,et al.  The Rank Transform Method in Some Two-Factor Designs , 1990 .

[10]  J. D. Hood,et al.  Visual control of balance in cerebellar and parkinsonian syndromes. , 1990, Brain : a journal of neurology.

[11]  James Theiler,et al.  Testing for nonlinearity in time series: the method of surrogate data , 1992 .

[12]  G. L. Thompson.  A Unified Approach to Rank Tests for Multivariate and Repeated Measures Designs , 1991 .

[13]  M. Schieppati,et al.  Free and supported stance in Parkinson's disease. The effect of posture and 'postural set' on leg muscle responses to perturbation, and its relation to the severity of the disease. , 1991, Brain : a journal of neurology.

[14]  F. Horak,et al.  Postural inflexibility in parkinsonian subjects , 1992, Journal of the Neurological Sciences.

[15]  Karl M. Newell,et al.  Variability and Motor Control , 1993 .

[16]  W Freedman,et al.  Nonstationary properties of postural sway. , 1993, Journal of biomechanics.

[17]  C L Webber,et al.  Dynamical assessment of physiological systems and states using recurrence plot strategies. , 1994, Journal of applied physiology.

[18]  A. El-Jaroudi,et al.  Time-frequency analysis of postural sway , 1994, Proceedings of 1994 28th Asilomar Conference on Signals, Systems and Computers.

[19]  M Schieppati,et al.  The limits of equilibrium in young and elderly normal subjects and in parkinsonians. , 1994, Electroencephalography and clinical neurophysiology.

[20]  Michael G. Akritas,et al.  Fully Nonparametric Hypotheses for Factorial Designs I: Multivariate Repeated Measures Designs , 1994 .

[21]  C. J. Luca,et al.  Open-loop and closed-loop postural control mechanisms in Parkinson's disease: increased mediolateral activity during quiet standing , 1995, Neuroscience Letters.

[22]  C L Webber,et al.  Influence of isometric loading on biceps EMG dynamics as assessed by linear and nonlinear tools. , 1995, Journal of applied physiology.

[23]  A. Opstal.  Dynamic Patterns: The Self-Organization of Brain and Behavior , 1995 .

[24]  John Milton,et al.  Dynamic diseases in neurology and psychiatry. , 1995, Chaos.

[25]  Hugh C. Davis,et al.  To embed or not to embed… , 1995, CACM.

[26]  M. Contin,et al.  Postural stability in Parkinson's disease: the effects of disease severity and acute levodopa dosing. , 1996, Parkinsonism & related disorders.

[27]  Charles L. Webber,et al.  Assessing Deterministic Structures in Physiological Systems Using Recurrence Plot Strategies , 1996 .

[28]  Holger Dette,et al.  Box-Type Approximations in Nonparametric Factorial Designs , 1997 .

[29]  Gavan Lintern,et al.  Dynamic patterns: The self-organization of brain and behavior , 1997, Complex.

[30]  A. Goldberger.  Fractal Variability Versus Pathologic Periodicity: Complexity Loss and Stereotypy in Disease , 1997, Perspectives in biology and medicine.

[31]  Michael T. Turvey,et al.  Visual Influences on Center of Pressure Dynamics in Upright Posture , 1998 .

[32]  E. Bradley,et al.  Recurrence plots of experimental data: To embed or not to embed? , 1998, Chaos.

[33]  P Rougier,et al.  Automatic determination of the transition between successive control mechanisms in upright stance assessed by modelling of the centre of pressure. , 1999, Archives of physiology and biochemistry.

[34]  M. Turvey,et al.  Recurrence quantification analysis of postural fluctuations. , 1999, Gait & posture.

[35]  N. Barbaro,et al.  Effect of pallidotomy on postural control and motor function in Parkinson disease. , 1999, Archives of neurology.

[36]  M T Turvey,et al.  Specificity of postural sway to the demands of a precision task. , 2000, Gait & posture.

[37]  M. Morris,et al.  Postural instability in Parkinson's disease: a comparison with and without a concurrent task. , 2000, Gait & posture.

[38]  A Cappello,et al.  An improved technique for the extraction of stochastic parameters from stabilograms. , 2000, Gait & posture.

[39]  Vladimir M. Zatsiorsky,et al.  On the fractal properties of natural human standing , 2000, Neuroscience Letters.

[40]  Robert J. Peterka,et al.  Postural control model interpretation of stabilogram diffusion analysis , 2000, Biological Cybernetics.

[41]  Tjeerd M. H. Dijkstra,et al.  A gentle introduction to the dynamic set-point model of human postural control during perturbed stance , 2000 .

[42]  R. Emmerik,et al.  On Variability and Stability in Human Movement , 2000 .

[43]  B. Bloem,et al.  “Stops walking when talking” does not predict falls in Parkinson's disease , 2000, Annals of neurology.

[44]  J W Błaszczyk,et al.  Postural stability and fractal dynamics. , 2001, Acta neurobiologiae experimentalis.

[45]  Vladimir M. Zatsiorsky,et al.  Long-range correlations in human standing , 2001 .

[46]  R. van Emmerik,et al.  Stability boundaries and lateral postural control in parkinson's disease. , 2001, Motor control.

[47]  F. Horak,et al.  Effects of deep brain stimulation and levodopa on postural sway in Parkinson's disease , 2002, Journal of neurology, neurosurgery, and psychiatry.

[48]  K. Newell,et al.  Changing complexity in human behavior and physiology through aging and disease , 2002, Neurobiology of Aging.

[49]  Karl M Newell,et al.  Complexity in aging and disease: response to commentaries , 2002, Neurobiology of Aging.

[50]  M. Turvey,et al.  Variability and Determinism in Motor Behavior , 2002, Journal of motor behavior.

[51]  L. Nashner,et al.  Postural instability in idiopathic Parkinson's disease: the role of medication and unilateral pallidotomy. , 2002, Brain : a journal of neurology.

[52]  C. Peng,et al.  What is physiologic complexity and how does it change with aging and disease? , 2002, Neurobiology of Aging.

[53]  M. Woollacott,et al.  Attention and the control of posture and gait: a review of an emerging area of research. , 2002, Gait & posture.

[54]  Ville Kampman,et al.  Analysis of sway in Parkinson's disease using a new inclinometry‐based method , 2002, Movement disorders : official journal of the Movement Disorder Society.

[55]  M. Mouradian.  Recent advances in the genetics and pathogenesis of Parkinson disease , 2002, Neurology.

[56]  M. Bove,et al.  Effect of cognitive and motor tasks on postural stability in Parkinson's disease: A posturographic study , 2003, Movement disorders : official journal of the Movement Disorder Society.

[57]  Lucy Yardley,et al.  Does articulation contribute to modifications of postural control during dual-task paradigms? , 2003, Brain research. Cognitive brain research.

[58]  Alexandre Legros,et al.  A Methodological Note on Nonlinear Time Series Analysis: Is the Open-and Closed-Loop Model of Collins and De Luca (1993) a Statistical Artifact? , 2003, Journal of motor behavior.

[59]  C H Lücking,et al.  Effect of chronic bilateral subthalamic nucleus (STN) stimulation on postural control in Parkinson's disease. , 2003, Brain : a journal of neurology.

[60]  Michael A. Riley,et al.  Recurrence analysis of human postural sway during the sensory organization test , 2003, Neuroscience Letters.

[61]  J. Frank,et al.  Fear of falling and postural control in Parkinson's disease , 2003, Movement disorders : official journal of the Movement Disorder Society.

[62]  J. J. Collins,et al.  The effects of visual input on open-loop and closed-loop postural control mechanisms , 2004, Experimental Brain Research.

[63]  Günther Deuschl,et al.  Falls in frequent neurological diseases--prevalence, risk factors and aetiology. , 2004, Journal of neurology.

[64]  J. Zbilut,et al.  Recurrence Quantification Analysis of Nonlinear Dynamical Systems , 2004 .

[65]  K. Shockley,et al.  Application of Recurrence Quantification Analysis : Influence of Cognitive Activity on Postural Fluctuations , 2004 .

[66]  J. Collins,et al.  Open-loop and closed-loop control of posture: A random-walk analysis of center-of-pressure trajectories , 2004, Experimental Brain Research.

[67]  T. Mergner,et al.  Abnormal resonance behavior of the postural control loop in Parkinson’s disease , 2004, Experimental Brain Research.

[68]  Michael A. Riley,et al.  Dynamic patterns of postural sway in ballet dancers and track athletes , 2005, Experimental Brain Research.

[69]  F. Horak,et al.  Comparison between subthalamic nucleus and globus pallidus internus stimulation for postural performance in Parkinson's disease. , 2004, Gait & posture.

[70]  M A Riley,et al.  Effects of Visual and Auditory Short-Term Memory Tasks on the Spatiotemporal Dynamics and Variability of Postural Sway , 2005, Journal of motor behavior.

[71]  K. M. Newell,et al.  Stochastic processes in postural center-of-pressure profiles , 2006, Experimental Brain Research.