Insulin resistance is a characteristic feature of primary hypertension independent of obesity.

[1]  J. Cederholm,et al.  Glucose intolerance in middle-aged subjects--a cause of hypertension? , 2009, Acta medica Scandinavica.

[2]  P. Björntorp,et al.  Body composition and glucose metabolism in hypertensive middle-aged males. , 2009, Acta medica Scandinavica.

[3]  C. Berne,et al.  Sensitivity to insulin during treatment with atenolol and metoprolol: a randomised, double blind study of effects on carbohydrate and lipoprotein metabolism in hypertensive patients. , 1989, BMJ.

[4]  E. Bonora,et al.  Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance. , 1989, The New England journal of medicine.

[5]  S. Haffner,et al.  Increased insulin concentrations in nondiabetic offspring of diabetic parents. , 1988, The New England journal of medicine.

[6]  Roy Taylor,et al.  HYPERTENSION AND HYPERINSULINAEMIA: A RELATION IN DIABETES BUT NOT ESSENTIAL HYPERTENSION , 1988, The Lancet.

[7]  S. Haffner,et al.  Hyperinsulinemia, upper body adiposity, and cardiovascular risk factors in non-diabetics. , 1988, Metabolism: clinical and experimental.

[8]  G. Reaven,et al.  Resistance to insulin-stimulated-glucose uptake in patients with hypertension. , 1988, The Journal of clinical endocrinology and metabolism.

[9]  E. Ferrannini,et al.  Insulin resistance in essential hypertension. , 1987, The New England journal of medicine.

[10]  G. Reaven,et al.  Abnormalities of carbohydrate and lipid metabolism in patients with hypertension. , 1987, Archives of internal medicine.

[11]  F. Cambien,et al.  Body Mass, Blood Pressure, Glucose, and Lipids: Does Plasma Insulin Explain Their Relationships? , 1987, Arteriosclerosis.

[12]  S. Haffner,et al.  Do Upper-Body and Centralized Adiposity Measure Different Aspects of Regional Body-Fat Distribution? Relationship to Non-Insulin-Dependent Diabetes Mellitus, Lipids, and Lipoproteins , 1987, Diabetes.

[13]  J. Jeppsson,et al.  Measurement of hemoglobin A1c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated. , 1986, Clinical chemistry.

[14]  W. Castelli,et al.  The triglyceride issue: a view from Framingham. , 1986, American heart journal.

[15]  E. Ferrannini,et al.  Evidence for an association of high blood pressure and hyperinsulinemia in obese man. , 1986, The Journal of clinical endocrinology and metabolism.

[16]  G. Borkan,et al.  Relationship of Fat Distribution to Glucose Tolerance: Results of Computed Tomography in Male Participants of the Normative Aging Study , 1986, Diabetes.

[17]  A. Krolewski,et al.  Is Insulin the Link Between Hypertension and Obesity? , 1985, Hypertension.

[18]  P. Björntorp,et al.  The Influence of Body Fat Distribution on the Incidence of Diabetes Mellitus: 13.5 Years of Follow-up of the Participants in the Study of Men Born in 1913 , 1985, Diabetes.

[19]  C. Bouchard,et al.  Evidence for a regional component of body fatness in the association with serum lipids in men and women. , 1985, Metabolism: clinical and experimental.

[20]  G. Reaven,et al.  Insulin and blood pressure in obesity. , 1985, Hypertension.

[21]  S. MacMahon,et al.  Plasma Lipoprotein Levels in Treated and Untreated Hypertensive Men and Women: The National Heart Foundation of Australia Risk Factor Prevalence Study , 1985, Arteriosclerosis.

[22]  H. Halkin,et al.  Hyperinsulinemia. A link between hypertension obesity and glucose intolerance. , 1985, The Journal of clinical investigation.

[23]  K. Pennert,et al.  Distribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden. , 1984, British medical journal.

[24]  A. Kissebah,et al.  Relationship between skeletal muscle insulin resistance, insulin-mediated glucose disposal, and insulin binding. Effects of obesity and body fat topography. , 1984, The Journal of clinical investigation.

[25]  P. Björntorp,et al.  Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913. , 1984, British medical journal.

[26]  S. MacMahon,et al.  Obesity, alcohol consumption and blood pressure in Australian men and women. The National Heart Foundation of Australia Risk Factor Prevalence Study. , 1984, Journal of hypertension.

[27]  L. Sjöström,et al.  Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. , 1983, The Journal of clinical investigation.

[28]  R. Moore,et al.  Effects of insulin upon ion transport. , 1983, Biochimica et biophysica acta.

[29]  R. DeFronzo,et al.  Regulation of Splanchnic and Peripheral Glucose Uptake by Insulin and Hyperglycemia in Man , 1983, Diabetes.

[30]  R. DeFronzo,et al.  The effect of growth hormone on glucose metabolism and insulin secretion in man. , 1982, The Journal of clinical endocrinology and metabolism.

[31]  A. Kissebah,et al.  Relation of Body Fat Distribution to Metabolic Complications of Obesity , 1982 .

[32]  L. Mandarino,et al.  Mechanism and Significance of Insulin Resistance in Non-insulin-dependent Diabetes Mellitus , 1981, Diabetes.

[33]  G. Reaven,et al.  Diabetic Hypertriglyceridemia: Evidence for Three Clinical Syndromes , 1981, Diabetes.

[34]  L. Mandarino,et al.  Dose-response characteristics for effects of insulin on production and utilization of glucose in man. , 1981, The American journal of physiology.

[35]  L. Seigler,et al.  Separation of serum high-density lipoprotein for cholesterol determination: ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride. , 1981, Clinical chemistry.

[36]  J W Rowe,et al.  Effect of Insulin and Glucose Infusions on Sympathetic Nervous System Activity in Normal Man , 1981, Diabetes.

[37]  G. Reaven,et al.  Relationship between insulin resistance, insulin secretion, very low density lipoprotein kinetics, and plasma triglyceride levels in normotriglyceridemic man. , 1981, Metabolism: clinical and experimental.

[38]  R. DeFronzo,et al.  Glucose clamp technique: a method for quantifying insulin secretion and resistance. , 1979, The American journal of physiology.

[39]  J. Stamler,et al.  Weight and blood pressure. Findings in hypertension screening of 1 million Americans , 1978 .

[40]  H. Keen,et al.  Glucose tolerance and blood pressure in two population samples: their relation to diabetes mellitus and hypertension. , 1978, International journal of epidemiology.

[41]  A. Dyer,et al.  Multivariate analysis of the relationship of seven variables to blood pressure: findings of the Chicago Heart Association Detection Project in Industry, 1967-1972. , 1975, Journal of chronic diseases.

[42]  G. Reaven,et al.  Reappraisal of the role of insulin in hypertriglyceridemia. , 1974, The American journal of medicine.

[43]  S. Tjoa,et al.  PRACTOLOL IN THE CONTROL OF INTRAOCULAR TENSION , 1974 .

[44]  R. Goldrick,et al.  Lipolysis and lipogenesis from glucose in human fat cells of different sizes. Effects of insulin, epinephrine, and theophylline. , 1970, The Journal of clinical investigation.

[45]  F. Epstein,et al.  Overweight and Hypertension: A Review , 1969, Circulation.

[46]  G. Reaven,et al.  Role of insulin in endogenous hypertriglyceridemia. , 1967, The Journal of clinical investigation.

[47]  R. Luft,et al.  On the intravenous glucose tolerance test. , 1957, Acta endocrinologica.

[48]  R. Havel,et al.  The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. , 1955, The Journal of clinical investigation.

[49]  J. Wang,et al.  Serum insulin and blood pressure in an obese population. , 1986, International journal of obesity.

[50]  R N Bergman,et al.  Assessment of insulin sensitivity in vivo. , 1985, Endocrine reviews.