Minimally invasive pseudo-continuous blood glucose monitoring: Results from in-vitro and in-vivo testing of the e-Mosquito

In this paper, we present a wearable microsystem for minimally invasive, autonomous and pseudo-continuous blood glucose monitoring that addresses growing demand for replacing tedious fingerpricking tests for diabetic patients. Unlike the prevalent solutions that estimate blood glucose levels from interstitial fluids or tears, our approach uses a novel wearable microsystem design to extract a whole blood sample from a small lanced s in wound and to directly measure the blood glucose level from it. Both in-vitro and in-vivo testing results illustrate the method.