Hydrazinecarbonyl-thiazol-2-acetamides with pronounced apoptotic behavior: synthesis, in vitro/in vivo anti-proliferative activity and molecular modeling simulations.
暂无分享,去创建一个
[1] Mariam A. Ghaly,et al. New thiazole-based derivatives as EGFR/HER2 and DHFR inhibitors: Synthesis, molecular modeling simulations and anticancer activity. , 2022, European journal of medicinal chemistry.
[2] S. Minucci,et al. Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: a case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitors , 2022, Journal of Molecular Structure.
[3] H. Daabees,et al. New functionalized 6‐thienylpyrimidine‐5‐carbonitriles as antiproliferative agents against human breast cancer cells , 2021, Archiv der Pharmazie.
[4] Riham F. George,et al. 3-Methyl-imidazo[2,1-b]thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations. , 2021, Bioorganic chemistry (Print).
[5] Amr M Hilal Abdou,et al. Novel thienopyrimidine-aminothiazole hybrids: Design, synthesis, antimicrobial screening, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and VEGFR-2 inhibition. , 2021, Bioorganic chemistry.
[6] S. Bräse,et al. Design, Synthesis, and Molecular Docking of Paracyclophanyl-Thiazole Hybrids as Novel CDK1 Inhibitors and Apoptosis Inducing Anti-Melanoma Agents , 2020, Molecules.
[7] Mohamed El-Shafey,et al. Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma , 2020, Molecules.
[8] E. E. Habib,et al. Antibacterial, antibiofilm and molecular modeling study of some antitumor thiazole based chalcones as a new class of DHFR inhibitors. , 2019, Microbial pathogenesis.
[9] M. Shoaib,et al. Synthesis, molecular modelling and biological evaluation of tetrasubstituted thiazoles towards cholinesterase enzymes and cytotoxicity studies. , 2018, Bioorganic chemistry.
[10] A. Leite,et al. Synthesis, anticancer activity and mechanism of action of new thiazole derivatives. , 2018, European journal of medicinal chemistry.
[11] J. Bariwal,et al. Review on EGFR Inhibitors: Critical Updates. , 2016, Mini reviews in medicinal chemistry.
[12] R. F. Angawi,et al. Synthesis, biological evaluation and molecular docking studies of thiazole-based pyrrolidinones and isoindolinediones as anticonvulsant agents , 2015, Medicinal Chemistry Research.
[13] A. Pandey,et al. Drug Targets for Cancer Treatment: An Overview , 2015 .
[14] P. Bedi,et al. Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids. , 2014, European journal of medicinal chemistry.
[15] K. Mohamed,et al. Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. , 2013, European journal of medicinal chemistry.
[16] D. Anil Kumar,et al. Synthesis, interaction with DNA, cytotoxicity, cell cycle arrest and apoptotic inducing properties of ruthenium(II) molecular "light switch" complexes. , 2013, European journal of medicinal chemistry.
[17] Y. Yatabe,et al. Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer , 2010, The FEBS journal.
[18] K. K. Lo,et al. Luminescent biological probes derived from ruthenium(II) estradiol polypyridine complexes. , 2008, Inorganic chemistry.
[19] C. Lipinski. Lead- and drug-like compounds: the rule-of-five revolution. , 2004, Drug discovery today. Technologies.
[20] M. Paul,et al. Tyrosine kinase – Role and significance in Cancer , 2004, International journal of medical sciences.
[21] A. Abadi,et al. Synthesis and Antitumor Activity of 9‐Anilino, Phenylhydrazino, and Sulphonamido Analogs of 2‐ or 4‐Methoxy‐6‐nitroacridines , 1998, Archiv der Pharmazie.
[22] V. Cody,et al. Methotrexate-resistant Variants of Human Dihydrofolate Reductase with Substitutions of Leucine 22 , 1995, The Journal of Biological Chemistry.
[23] T. Hunter,et al. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. , 1988, Science.
[24] F. Denizot,et al. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. , 1986, Journal of immunological methods.
[25] T. Mosmann. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.
[26] O. Frankfurt,et al. EFFECT OF METHOTREXATE ON THE CELL CYCLE OF L1210 LEUKEMIA , 1976, Cell and tissue kinetics.
[27] V. Revankar,et al. Synthesis, structure, electrochemistry and spectral characterization of (D-glucopyranose)-4-phenylthiosemicarbazide metal complexes and their antitumor activity against Ehrlich ascites carcinoma in Swiss albino mice. , 2010, European journal of medicinal chemistry.
[28] T. Hsia,et al. Baicalein induced in vitro apoptosis undergo caspases activity in human promyelocytic leukemia HL-60 cells. , 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.