The benefits of close collaboration with industry for graduate/post-graduate professional students have been repeatedly emphasized in the literatures. This paper discusses the adoption and operation of curriculum which when taken up in professional colleges may help making of entrepreneurs when the student completes his academic courses. Sample groups of professional students can act as representative samples and their inclinations towards entrepreneurship - on the basis of behavioral traits, passion, drive, risk taking capacity - can be tested by administering structured questionnaire to them, so as to ascertain how effective is the inclusion of Industry-Institute-Interaction in the academic curriculum. Problem-based learning (PBL) by way of academic projects can be relevant to the specific field. This paper suggests the necessity of Industry-Institute-Interaction cell to ensure that the industry institute collaboration proceeds smoothly and helps in making of entrepreneurs.