C-kit mutations and mast cell disorders. A model of activating mutations of growth factor receptors.

[1]  W. Vainchenker,et al.  A new c‐kit mutation in a case of aggressive mast cell disease , 1997, British journal of haematology.

[2]  A. Bernstein,et al.  A point mutation in the catalytic domain of c-kit induces growth factor independence, tumorigenicity, and differentiation of mast cells. , 1996, Blood.

[3]  Laura H. Tang,et al.  Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm , 1996, Nature Genetics.

[4]  Y. Suzuki,et al.  Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[5]  H. Kitayama,et al.  Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines. , 1995, Blood.

[6]  S. Galli,et al.  Mast cell and basophil development. , 1994, Current opinion in hematology.

[7]  L. Ashman,et al.  Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. , 1993, The Journal of clinical investigation.

[8]  R. Spritz,et al.  Organization and nucleotide sequence of the human KIT (mast/stem cell growth factor receptor) proto-oncogene. , 1992, Oncogene.

[9]  R. Fleischman Human piebald trait resulting from a dominant negative mutant allele of the c-kit membrane receptor gene. , 1992, The Journal of clinical investigation.

[10]  D. Metcalfe,et al.  Classification and diagnosis of mastocytosis: current status. , 1991, The Journal of investigative dermatology.

[11]  A. Ullrich,et al.  Human proto‐oncogene c‐kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. , 1987, The EMBO journal.