According to one embodiment, for forming a three-dimensional (3D) nanoparticles assembly method may include surface-enhanced spectroscopy (SES) is deposited onto the nano element refers to corresponding tips, wherein nano-fingers arranged in a close enough proximity to each other, such that the nano-tip plurality sets of adjacent fingers can be nano-fingers close enough proximity to each other, so that on the tip member SES nano refers to binding together the partial collapse. The method further comprises the nano-fingers toward the fingers of the adjacent nano nano refers to partial collapse, so that the corresponding plurality of sets of the plurality of nano-elements SES refers opposite and in close proximity to one another than the corresponding cluster SES element is formed, to be connected additional particles are introduced into the tuft element SES, SES and the nano cluster separation element fingers.