DNA topoisomerase II inhibition and gene amplification in V79/B7 cells.

[1]  A. Di Leonardo,et al.  Nalidixic acid-resistant V79 cells with reduced DNA topoisomerase II activity and amplification prone phenotype. , 1992, Mutation research.

[2]  Thea D. Tlsty,et al.  Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 , 1992, Cell.

[3]  G. Wahl,et al.  Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles , 1992, Cell.

[4]  G. Wahl,et al.  Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events. , 1992, Mutation research.

[5]  G. Wahl,et al.  A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. , 1991, Genes & development.

[6]  W. Morgan,et al.  X-ray induction of methotrexate resistance due todhfr gene amplification , 1990, Somatic cell and molecular genetics.

[7]  G. Wahl,et al.  Recent progress in understanding mechanisms of mammalian DNA amplification , 1989, Cell.

[8]  P. Dijkwel,et al.  Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells , 1988, Molecular and cellular biology.

[9]  P. Degan,et al.  Chromosome aberrations associated with CAD gene amplification in Chinese hamster cultured cells. , 1988, Mutation research.

[10]  W. Morgan,et al.  The role of acentric chromosome fragments in gene amplification , 1987, Somatic cell and molecular genetics.

[11]  O. Hyrien,et al.  A hotspot for novel amplification joints in a mosaic of Alu‐like repeats and palindromic A + T‐rich DNA. , 1987, The EMBO journal.

[12]  T. Meyer,et al.  Enhancement of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA amplification in a Simian virus 40-transformed Chinese hamster cell line by 3-aminobenzamide. , 1987, Cancer research.

[13]  S. Gattoni‐Celli,et al.  Carcinogen induced asynchronous replication of polyoma DNA is mediated by a trans-acting factor. , 1986, Carcinogenesis.

[14]  R T Schimke,et al.  Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[15]  S. J. Berger,et al.  Poly(ADP-ribose) Polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis. , 1983, Biochemistry.

[16]  G R Stark,et al.  Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells. , 1979, The Journal of biological chemistry.

[17]  W. Morgan,et al.  Poly(ADP-ribose)polymerase: a perplexing participant in cellular responses to DNA breakage. , 1991, Mutation research.

[18]  L. Kapp,et al.  Replication intermediates as substrates for DNA rearrangements. , 1991, Mutation research.

[19]  L. Liu,et al.  DNA topoisomerase poisons as antitumor drugs. , 1989, Annual review of biochemistry.

[20]  A. Di Leonardo,et al.  Induction of CAD gene amplification by restriction endonucleases in V79,B7 Chinese hamster cells. , 1989, Mutation research.

[21]  Stark Gr.  DNA amplification in drug resistant cells and in tumours. , 1986 .