DIALYSIS-RELATED CERVICAL AMYLOIDOMA PRESENTING WITH QUADRIPLEGIA

Patients with end-stage renal disease may develop a variety of osteoarticular complications (1). Dialysis-related amyloidosis (DRA) secondary to β2-microglobulin deposits is a common osteoarticular complication of long-term dialysis patients, and is responsible for significant morbidity with potential mortality (2). β2-microglobulin deposition in osteoarticular structure is clinically manifested by carpal tunnel syndrome, cystic bone diseases, or destructive osteoarthropathies (3,4). Localized amyloid tumor, also known as amyloidoma, is a nodular mass of amyloid deposits. Although it is rare, cervical amyloidoma has been reported in patients with primary amyloidosis (5). We reported on a chronic dialysis patient with cervical amyloidoma, which resulted in numbness of the lower extremities and sudden quadriplegia. The neurological manifestation was reversible and the patient was ambulatory after surgical removal of the amyloidoma.