Bcl-w promotes cell invasion by blocking the invasion-suppressing action of Bax.

[1]  Nico Tjandra,et al.  Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol , 2011, Cell.

[2]  Keshav K. Singh,et al.  NADPH oxidase 4 is an oncoprotein localized to mitochondria , 2010, Cancer biology & therapy.

[3]  I. Nishimoto,et al.  Expression of Bcl‐2 family proteins and association with clinicopathological characteristics of oral squamous cell carcinoma , 2010, Histopathology.

[4]  A. Daiber Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species. , 2010, Biochimica et biophysica acta.

[5]  Sang-Gu Hwang,et al.  Bcl‐XL and STAT3 mediate malignant actions of γ‐irradiation in lung cancer cells , 2010, Cancer science.

[6]  Y. Yun,et al.  Sustained expression of NADPH oxidase 4 by p38 MAPK-Akt signaling potentiates radiation-induced differentiation of lung fibroblasts , 2010, Journal of Molecular Medicine.

[7]  R. Preissner,et al.  Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma , 2010, The Journal of cell biology.

[8]  S. Pervaiz,et al.  Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2 , 2010, Cell Death and Differentiation.

[9]  R. Kramer,et al.  Bcl-2 Overexpression Induces a Partial Epithelial to Mesenchymal Transition and Promotes Squamous Carcinoma Cell Invasion and Metastasis , 2010, Molecular Cancer Research.

[10]  H. Um,et al.  Signaling components involved in Bcl-w-induced migration of gastric cancer cells. , 2009, Cancer letters.

[11]  John Calvin Reed,et al.  Bcl-2 family proteins and cancer , 2008, Oncogene.

[12]  Eun Mi Kim,et al.  Amplification of the gamma-irradiation-induced cell death pathway by reactive oxygen species in human U937 cells. , 2008, Cellular signalling.

[13]  G. Oyler,et al.  The C-terminal transmembrane domain of Bcl-xL mediates changes in mitochondrial morphology. , 2008, Biophysical journal.

[14]  D. Hanahan,et al.  Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion , 2007, PLoS biology.

[15]  S. Cory,et al.  The Bcl-2 apoptotic switch in cancer development and therapy , 2007, Oncogene.

[16]  Peter Storz,et al.  Mitochondrial ROS--radical detoxification, mediated by protein kinase D. , 2007, Trends in cell biology.

[17]  H. Um,et al.  Link between Mitochondria and NADPH Oxidase 1 Isozyme for the Sustained Production of Reactive Oxygen Species and Cell Death* , 2006, Journal of Biological Chemistry.

[18]  A. Shah,et al.  Transmitting biological information using oxygen: reactive oxygen species as signalling molecules in cardiovascular pathophysiology. , 2006, Cardiovascular research.

[19]  M. Weller,et al.  BCL-xL: time-dependent dissociation between modulation of apoptosis and invasiveness in human malignant glioma cells , 2006, Cell Death and Differentiation.

[20]  D. Andrews,et al.  Bcl‐2 changes conformation to inhibit Bax oligomerization , 2006, The EMBO journal.

[21]  H. Um,et al.  Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1. , 2006, Cancer research.

[22]  C. Petito,et al.  Expression of the Antiapoptotic Proteins Clusterin and Bcl-2 in Laryngeal Squamous Cell Carcinomas , 2006, Tumor Biology.

[23]  F. Roviello,et al.  Bcl-2 expression correlates with lymphovascular invasion and long-term prognosis in breast cancer , 2006, Breast Cancer Research and Treatment.

[24]  T. Kuwana,et al.  PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53 , 2005, Science.

[25]  Y. C. Lee,et al.  Sp1 elements in SULT2B1b promoter and 5′‐untranslated region of mRNA: Sp1/Sp2 induction and augmentation by histone deacetylase inhibition , 2005, FEBS letters.

[26]  Kyusam Choi,et al.  Bcl-2 promotes invasion and lung metastasis by inducing matrix metalloproteinase-2. , 2005, Cancer research.

[27]  Tanja Woyke,et al.  Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. , 2005, Neoplasia.

[28]  S. Matsuda,et al.  Prognostic significance of Bcl-xL in human hepatocellular carcinoma. , 2004, Surgery.

[29]  John Calvin Reed,et al.  Conversion of Bcl-2 from Protector to Killer by Interaction with Nuclear Orphan Receptor Nur77/TR3 , 2004, Cell.

[30]  C. Borner,et al.  Bcl-w(edding) with mitochondria. , 2004, Trends in cell biology.

[31]  B. Oh,et al.  Unique structural features of a BCL-2 family protein CED-9 and biophysical characterization of CED-9/EGL-1 interactions , 2003, Cell Death and Differentiation.

[32]  Suzanne Cory,et al.  The Bcl-2 family: roles in cell survival and oncogenesis , 2003, Oncogene.

[33]  K. Gehring,et al.  Solution Structure of Human BCL-w , 2003, Journal of Biological Chemistry.

[34]  M. Lackmann,et al.  The structure of Bcl‐w reveals a role for the C‐terminal residues in modulating biological activity , 2003, The EMBO journal.

[35]  H. Um,et al.  Bcl-w is expressed in a majority of infiltrative gastric adenocarcinomas and suppresses the cancer cell death by blocking stress-activated protein kinase/c-Jun NH2-terminal kinase activation. , 2003, Cancer research.

[36]  S. Cory,et al.  The Bcl2 family: regulators of the cellular life-or-death switch , 2002, Nature Reviews Cancer.

[37]  H. Um,et al.  Adaptive concentrations of hydrogen peroxide suppress cell death by blocking the activation of SAPK/JNK pathway. , 2001, Journal of cell science.

[38]  C. Print,et al.  Tissue expression and subcellular localization of the pro-survival molecule Bcl-w , 2001, Cell Death and Differentiation.

[39]  B. Dörken,et al.  Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[40]  T. Gotow,et al.  Selective localization of Bcl-2 to the inner mitochondrial and smooth endoplasmic reticulum membranes in mammalian cells , 2000, Cell Death and Differentiation.

[41]  J. Toppari,et al.  Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis. , 2000, Molecular endocrinology.

[42]  Y. Hsu,et al.  Conformation of the Bax C‐terminus regulates subcellular location and cell death , 1999, The EMBO journal.

[43]  E. Brambilla,et al.  p53 mutant immunophenotype and deregulation of p53 transcription pathway (Bcl2, Bax, and Waf1) in precursor bronchial lesions of lung cancer. , 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

[44]  C. Leonetti,et al.  Bcl‐2 overexpression enhances the metastatic potential of a human breast cancer line , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[45]  T. Oltersdorf,et al.  Structural and Functional Complementation of an Inactive Bcl-2 Mutant by Bax Truncation* , 1997, The Journal of Biological Chemistry.