A Study on Utilization Pattern of Antibiotics for the Complicated Urinary Tract Infections in a Tertiary Care Centre

3 Abstract: A drug utilization pattern of antibiotics for complicated urinary tract infections in 100 cases above 18years of age was done at Sri Ramachandra Medical College and Research Institute. The antibiotic sensitivity profile of the microorganism causing urinary tract infections was studied in age group between 18-60 yrs of either sex as in patients ward and diagnosed as urinary tract infection. The patients with significant bacteriuria (> 10 CFU/ ml) were treated with antibiotics Cephalosporin's, Amikacin, Fluroquinolones, Amoxicillin + 5 Clavulanic acid and Linezolid.The antibiotic sensitivity profile of the microorganism causing urinary tract infections were studied. The incidence of urinary tract infections was more or less equal in either sex. More than 2/3 of these cases were found in the age group of 18 to 60 years. The most common organisms isolated from the urine culture and sensitivity test was E.coli and the most commonly prescribed antibiotic was amikacin.

[1]  C. Kloft,et al.  In vitro pharmacodynamic models to determine the effect of antibacterial drugs. , 2010, The Journal of antimicrobial chemotherapy.

[2]  E. Ridgway,et al.  Rational use of antibiotics in surgery , 2005 .

[3]  C. J. Wilkowske General principles of antimicrobial therapy. , 1991, Mayo Clinic proceedings.

[4]  A. Whelton The aminoglycosides. , 1984, Clinical orthopaedics and related research.

[5]  C. Kunin RATIONAL use of antibiotics. , 1952, Lancet.