Dermoscopy, Digital Dermoscopy and Other Diagnostic Tools in the Early Detection of Melanoma and Follow-up of High-risk Skin Cancer Patients.

Early detection is a key strategy for reducing the mortality and economic burden associated with melanoma. Dermoscopy is a non-invasive and cost-effective tool for melanoma diagnosis, which has been shown to be a reliable and sensitive method for detecting early-stage skin cancer and reducing the number of unnecessary excisions. Patients at high risk of developing melanoma require long-term surveillance. Use of digital dermoscopy follow-up of these patients has led to improved outcomes. Combined follow-up programmes using total-body photography and digital dermoscopy have led to further improvements in early diagnosis and diagnostic accuracy. Dermoscopy is now widely used by dermatologists, but the public health impact of this tool is yet to be evaluated. Despite the clear advantages of dermoscopy and digital follow-up meth-ods, dermoscopy training and access to digital dermoscopy among dermatologists and general practitioners needs to be improved.

[1]  J. Malvehy,et al.  Dermoscopy, Confocal Microscopy and other Non-invasive Tools for the Diagnosis of Non-Melanoma Skin Cancers and Other Skin Conditions. , 2017, Acta dermato-venereologica.

[2]  G. Argenziano,et al.  Teledermatology and Mobile Applications in the Management of Patients with Skin Lesions. , 2017, Acta dermato-venereologica.

[3]  J. Nguyen,et al.  Patients avec mélanome de primitifs multiples de la base nationale française RIC-Mel ☆ , 2016 .

[4]  J. Malvehy,et al.  Association Between Confocal Morphologic Classification and Clinical Phenotypes of Multiple Primary and Familial Melanomas. , 2016, JAMA dermatology.

[5]  G. Argenziano,et al.  Factors driving the use of dermoscopy in Europe: a pan‐European survey , 2016, The British journal of dermatology.

[6]  S. Merrill,et al.  Worldwide cutaneous malignant melanoma incidences analyzed by sex, age, and skin type over time (1955–2007): Is HPV infection of androgenic hair follicular melanocytes a risk factor for developing melanoma exclusively in people of European-ancestry? , 2016, Dermato-endocrinology.

[7]  J. Malvehy,et al.  In vivo reflectance confocal microscopy of equivocal melanocytic lesions detected by digital dermoscopy follow‐up , 2015, Journal of the European Academy of Dermatology and Venereology : JEADV.

[8]  C. Longo,et al.  Integration of reflectance confocal microscopy in sequential dermoscopy follow‐up improves melanoma detection accuracy , 2015, The British journal of dermatology.

[9]  A. Hauschild,et al.  Melanoma early detection and awareness: how countries developing melanoma awareness programs could benefit from melanoma-proficient countries. , 2015, American journal of therapeutics.

[10]  L. Thomas,et al.  Overview of the use of dermoscopy in academic and non‐academic hospital centres in France: a nationwide survey , 2014, Journal of the European Academy of Dermatology and Venereology : JEADV.

[11]  Pascale Guitera,et al.  Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study. , 2014, JAMA dermatology.

[12]  R. Hofmann-Wellenhof,et al.  Impact of in vivo reflectance confocal microscopy on the number needed to treat melanoma in doubtful lesions , 2014 .

[13]  I Zalaudek,et al.  Meta‐analysis of digital dermoscopy follow‐up of melanocytic skin lesions: a study on behalf of the International Dermoscopy Society , 2013, Journal of the European Academy of Dermatology and Venereology : JEADV.

[14]  A. Marghoob,et al.  Clinical and dermoscopic characteristics of desmoplastic melanomas. , 2013, JAMA dermatology.

[15]  L. Thomas,et al.  Dermoscopy use by French private practice dermatologists: a nationwide survey , 2013, The British journal of dermatology.

[16]  J. Malvehy,et al.  Characterization of 1152 lesions excised over 10 years using total-body photography and digital dermatoscopy in the surveillance of patients at high risk for melanoma. , 2012, Journal of the American Academy of Dermatology.

[17]  C Legrand,et al.  Availability of digital dermoscopy in daily practice dramatically reduces the number of excised melanocytic lesions: results from an observational study , 2012, The British journal of dermatology.

[18]  L. Thomas,et al.  Dermoscopy of lentigo maligna melanoma: report of 125 cases , 2012, The British journal of dermatology.

[19]  Josep Malvehy,et al.  Benefits of total body photography and digital dermatoscopy ("two-step method of digital follow-up") in the early diagnosis of melanoma in patients at high risk for melanoma. , 2012, Journal of the American Academy of Dermatology.

[20]  Ken Kobayashi,et al.  Accuracy in melanoma detection: a 10-year multicenter survey. , 2012, Journal of the American Academy of Dermatology.

[21]  D. Troxel,et al.  Trends in Pathology Malpractice Claims , 2012, The American journal of surgical pathology.

[22]  J. Grob,et al.  Cognitive training with photographs as a new concept in an education campaign for self‐detection of melanoma: a pilot study in the community , 2011, Journal of the European Academy of Dermatology and Venereology : JEADV.

[23]  J. Malvehy,et al.  Melanomas detected in a follow-up program compared with melanomas referred to a melanoma unit. , 2011, Archives of dermatology.

[24]  Neil Savage,et al.  Early detection: Spotting the first signs , 2011, Nature.

[25]  E. Warshaw,et al.  Dermatoscopy use by US dermatologists: a cross-sectional survey. , 2010, Journal of the American Academy of Dermatology.

[26]  H. Welch,et al.  Overdiagnosis in cancer. , 2010, Journal of the National Cancer Institute.

[27]  A. Marghoob,et al.  Use of and beliefs about total body photography and dermatoscopy among US dermatology training programs: an update. , 2010, Journal of the American Academy of Dermatology.

[28]  H. Haenssle,et al.  Selection of patients for long-term surveillance with digital dermoscopy by assessment of melanoma risk factors. , 2010, Archives of dermatology.

[29]  I Zalaudek,et al.  Slow‐growing melanoma: a dermoscopy follow‐up study , 2010, The British journal of dermatology.

[30]  S Touzet,et al.  Dermoscopic features of acral lentiginous melanoma in a large series of 110 cases in a white population , 2009, The British journal of dermatology.

[31]  R. Kirsner,et al.  Disparity in melanoma: a trend analysis of melanoma incidence and stage at diagnosis among whites, Hispanics, and blacks in Florida. , 2009, Archives of dermatology.

[32]  C. Longo,et al.  In vivo microscopic features of nodular melanomas: dermoscopy, confocal microscopy, and histopathologic correlates. , 2008, Archives of dermatology.

[33]  R. Hofmann-Wellenhof,et al.  Three roots of melanoma. , 2008, Archives of dermatology.

[34]  Riccardo Bono,et al.  Dermoscopic evaluation of amelanotic and hypomelanotic melanoma. , 2008, Archives of dermatology.

[35]  S. Menzies,et al.  Dermoscopy compared with naked eye examination for the diagnosis of primary melanoma: a meta‐analysis of studies performed in a clinical setting , 2008, The British journal of dermatology.

[36]  Josep Malvehy,et al.  Time required for a complete skin examination with and without dermoscopy: a prospective, randomized multicenter study. , 2008, Archives of dermatology.

[37]  J. Lang Trends in melanoma epidemiology suggest three different types of melanoma , 2008 .

[38]  E. Feuer,et al.  SEER Cancer Statistics Review, 1975-2003 , 2006 .

[39]  Michael Binder,et al.  Limitations of dermoscopy in the recognition of melanoma. , 2005, Archives of dermatology.

[40]  D. Troxel,et al.  Pitfalls in the Diagnosis of Malignant Melanoma: Findings of a Risk Management Panel Study , 2003, The American journal of surgical pathology.

[41]  H. Kittler Use of digital dermoscopy to monitor melanocytic lesions: risks and benefits. , 2003, Journal of drugs in dermatology : JDD.

[42]  H. Kittler,et al.  Follow-up of melanocytic skin lesions with digital dermoscopy: risks and benefits. , 2004, Archives of dermatology.

[43]  A. Marghoob,et al.  Use of and beliefs about dermoscopy in the management of patients with pigmented lesions: a survey of dermatology residency programmes in the United States , 2002, Melanoma research.

[44]  L. Thomas,et al.  Dermoscopic examination of nail pigmentation. , 2002, Archives of dermatology.

[45]  J. Malvehy,et al.  Follow-up of melanocytic skin lesions with digital total-body photography and digital dermoscopy: a two-step method. , 2002, Clinics in dermatology.

[46]  W. Stolz,et al.  Dermatoscopy for facial pigmented skin lesions. , 2002, Clinics in dermatology.

[47]  H. Kittler,et al.  Diagnostic accuracy of dermoscopy. , 2002, The Lancet. Oncology.

[48]  H. Kittler,et al.  Risks and benefits of sequential imaging of melanocytic skin lesions in patients with multiple atypical nevi. , 2001, Archives of dermatology.

[49]  S. Menzies,et al.  Short-term digital surface microscopic monitoring of atypical or changing melanocytic lesions. , 2001, Archives of dermatology.

[50]  P. Aegerter,et al.  Is dermoscopy (epiluminescence microscopy) useful for the diagnosis of melanoma? Results of a meta-analysis using techniques adapted to the evaluation of diagnostic tests. , 2001, Archives of dermatology.

[51]  HywelC. Williams,et al.  Another sniffer dog for the clinic? , 2001, The Lancet.

[52]  H. Kittler,et al.  Follow-up of melanocytic skin lesions with digital epiluminescence microscopy: patterns of modifications observed in early melanoma, atypical nevi, and common nevi. , 2000, Journal of the American Academy of Dermatology.

[53]  J. Grob,et al.  Melanoma and tumor thickness: challenges of early diagnosis. , 1999, Archives of dermatology.

[54]  L. Thomas,et al.  Semiological Value of ABCDE Criteria in the Diagnosis of Cutaneous Pigmented Tumors , 1998, Dermatology.

[55]  HywelC. Williams,et al.  SNIFFER DOGS IN THE MELANOMA CLINIC? , 1989, The Lancet.

[56]  A. Ackerman No one should die of malignant melanoma. , 1985, Journal of the American Academy of Dermatology.