A Genome-Wide Association Study on Obesity and Obesity- Related Traits
暂无分享,去创建一个
[1] H. Makhlouf,et al. Pathologic criteria for nonalcoholic steatohepatitis: Interprotocol agreement and ability to predict liver‐related mortality , 2011, Hepatology.
[2] H. Cortez‐Pinto,et al. Apoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease , 2011, Diabetologia.
[3] D. Goulis,et al. Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis. , 2011, Metabolism: clinical and experimental.
[4] K. Eckardt,et al. Obesity-associated insulin resistance in skeletal muscle: Role of lipid accumulation and physical inactivity , 2011, Reviews in Endocrine and Metabolic Disorders.
[5] F. Toledo,et al. Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide , 2011, Diabetologia.
[6] Chris Day,et al. A position statement on NAFLD/NASH based on the EASL 2009 special conference. , 2010, Journal of hepatology.
[7] J. Duarte,et al. Lifelong physical activity modulation of the skeletal muscle mitochondrial proteome in mice. , 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.
[8] K. Petersen,et al. Lipid-induced insulin resistance: unravelling the mechanism , 2010, The Lancet.
[9] M. Tarnopolsky,et al. Aberrant Mitochondrial Homeostasis in the Skeletal Muscle of Sedentary Older Adults , 2010, PloS one.
[10] J. Kountouras,et al. The role of adiponectin in the pathogenesis and treatment of non‐alcoholic fatty liver disease , 2010, Diabetes, obesity & metabolism.
[11] R. DeFronzo,et al. Pathogenesis of Insulin Resistance in Skeletal Muscle , 2010, Journal of biomedicine & biotechnology.
[12] S. Menini,et al. Increased tumor necrosis factor α–converting enzyme activity induces insulin resistance and hepatosteatosis in mice , 2010, Hepatology.
[13] S. Toda,et al. Age-related fat deposition in multifidus muscle could be a marker for nonalcoholic fatty liver disease , 2010, Journal of Gastroenterology.
[14] G. Heigenhauser,et al. Skeletal muscle lipogenic protein expression is not different between lean and obese individuals: a potential factor in ceramide accumulation. , 2009, The Journal of clinical endocrinology and metabolism.
[15] S. Caldwell,et al. Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. , 2009, Journal of hepatology.
[16] R. DeFronzo,et al. Impaired regulation of the TNF-α converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans , 2009, Diabetologia.
[17] S. Menini,et al. Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. , 2009, Gastroenterology.
[18] A. Bonen,et al. Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals. , 2009, The American journal of clinical nutrition.
[19] A. Bonen,et al. PGC-1alpha-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptions. , 2008, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
[20] N. Turner,et al. Muscle insulin resistance: A case of fat overconsumption, not mitochondrial dysfunction , 2008, Proceedings of the National Academy of Sciences.
[21] Dong-Ho Han,et al. High-fat diets cause insulin resistance despite an increase in muscle mitochondria , 2008, Proceedings of the National Academy of Sciences.
[22] V. Schrauwen-Hinderling,et al. Lipid accumulation in non-adipose tissue and lipotoxicity , 2008, Physiology & Behavior.
[23] N. Turner,et al. Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle , 2007, Diabetes.
[24] Yiying Zhang,et al. Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance. , 2007, The Journal of clinical investigation.
[25] J. Hawley,et al. Mitochondrial function: use it or lose it , 2007, Diabetologia.
[26] Y. Boirie,et al. Chronological Approach of Diet‐induced Alterations in Muscle Mitochondrial Functions in Rats , 2007, Obesity.
[27] M. Holmqvist,et al. Long‐term follow‐up of patients with NAFLD and elevated liver enzymes , 2006, Hepatology.
[28] H. Cortez‐Pinto,et al. Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitis , 2006, European journal of gastroenterology & hepatology.
[29] G. Marchesini,et al. Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severity. , 2005, The Journal of clinical endocrinology and metabolism.
[30] O. Cummings,et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease , 2005, Hepatology.
[31] P. Ritz,et al. Muscle fat oxidative capacity is not impaired by age but by physical inactivity: association with insulin sensitivity , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[32] R. Turner,et al. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man , 1985, Diabetologia.
[33] R. DeFronzo,et al. Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. , 2004, Diabetes.
[34] S. Genuth. Lowering the criterion for impaired fasting glucose is in order. , 2003, Diabetes care.
[35] G. Marchesini,et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome , 2003, Hepatology.
[36] F. Schick,et al. Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity. , 2003, The Journal of clinical endocrinology and metabolism.
[37] G. Shulman,et al. Skeletal muscle lipid metabolism with obesity. , 2003, American journal of physiology. Endocrinology and metabolism.
[38] A. Herling,et al. Intramyocellular Lipid and Insulin Resistance a Longitudinal in Vivo H-spectroscopic Study in Zucker Diabetic Fatty Rats , 2022 .
[39] G. Shulman,et al. Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle* , 2002, The Journal of Biological Chemistry.
[40] Jing He,et al. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. , 2002, Diabetes.
[41] P. Scifo,et al. Normal insulin sensitivity and IMCL content in overweight humans are associated with higher fasting lipid oxidation. , 2002, American journal of physiology. Endocrinology and metabolism.
[42] K. Petersen,et al. Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity. , 2002, Diabetes.
[43] F. Schick,et al. Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans. , 2001, Diabetes.
[44] I. Batty,et al. Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells , 2001, Diabetologia.
[45] G. Dohm,et al. Lipid oxidation is reduced in obese human skeletal muscle. , 2000, American journal of physiology. Endocrinology and metabolism.
[46] G. Cooney,et al. Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle. , 2000, American journal of physiology. Endocrinology and metabolism.
[47] Simon C Watkins,et al. Intramuscular lipid content is increased in obesity and decreased by weight loss. , 2000, Metabolism: clinical and experimental.
[48] C. Kahn,et al. Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. , 2000, The Journal of clinical investigation.
[49] A. Goldberg,et al. Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men , 1996 .