论文信息 - Solvent Dependency in Regioselective Ring Openings of 3,4- and 2,3-Epoxy Alcohols with Diethylamine Hydrohalides.

Solvent Dependency in Regioselective Ring Openings of 3,4- and 2,3-Epoxy Alcohols with Diethylamine Hydrohalides.

Titanium-mediated ring openings of 3,4-epoxy-1-ols at the 4-position with diethylamine hydrohalides proceeded efficiently in dichloromethane, while the requisite openings of 2,3-epoxy-1-ols at the 3-position in benzene.

A. Murai | Lian‐xun Gao

[1] V. Martín,et al. Mild and stereocontrolled synthesis of iodo- and bromohydrins by halogen-tetrakis(isopropoxy)titanium opening of epoxy alcohols , 1990 .