论文信息 - A Case of Acute Insulin Poisoning

A Case of Acute Insulin Poisoning

A 32-year-old lady presented to the emergency department for suicidal attempt by self-injection of insulin (Protaphane 210 units). She developed repeated episodes of hypoglycaemia even with continuous intravenous infusion of 10% dextrose solution during observation. However, she did not develop serious complications of hypoglycaemia and was subsequently discharged after conservative treatment. Acute insulin poisoning is uncommon. The management of this uncommon poisoning is reviewed in this case report.

[1] W. Burnham,et al. Local excision of subcutaneous fat in the management of insulin overdose , 1986, The British journal of surgery.

[2] P. Kann,et al. Epidemiological assessment of 160 cases of insulin overdose recorded in a regional poisons unit. , 2004, International journal of clinical pharmacology and therapeutics.

[3] S. Hart,et al. Causes, management and morbidity of acute hypoglycaemia in adults requiring hospital admission. , 1998, QJM : monthly journal of the Association of Physicians.

[4] T. Delbridge,et al. Intentional massive insulin overdose: recognition and management. , 1993, Annals of emergency medicine.

[5] I. Campbell,et al. Suicidal insulin overdose managed by excision of insulin injection site. , 1982, British medical journal.

[6] J. A. Scarlett,et al. Factitious hypoglycemia. Diagnosis by measurement of serum C-peptide immunoreactivity and insulin-binding antibodies. , 1977, The New England journal of medicine.

[7] K. Soma,et al. Myocardial infarction with acute insulin poisoning--a case report. , 2000, Angiology.