论文信息 - Lipase-catalysed enantioselective acylation of N-protected or unprotected 2-aminoalkan-1-ols

Lipase-catalysed enantioselective acylation of N-protected or unprotected 2-aminoalkan-1-ols

Porcine pancreatic lipase (PPL) catalysed the acylation of 2-aminoalkan-1-ols; the enantiospecificity depends on the starting amino alcohol. The catalytic activity of the enzyme was markedly improved when the benzyl carbamate derivatives were used as substrates; in general, the enzyme displayed a high enantiospecificity.

S. Fernández | V. Gotor | F. Rebolledo | R. Brieva

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