Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer
暂无分享,去创建一个
Justin K. Huang | S. Signoretti | A. Hakimi | E. Jonasch | T. Choueiri | Jianjun Gao | Linghua Wang | G. Genovese | Jianhua Zhang | C. Bristow | T. Heffernan | G. Draetta | Tony Gutschner | S. Lundgren | R. Minelli | Li Zhang | E. Allen | S. Turajlic | K. Litchfield | K. Sircar | A. Viale | M. Peoples | N. Tannir | P. Msaouel | A. Futreal | A. Sgambato | Sanjana Srinivasan | A. Carugo | Z. Bakouny | V. Giuliani | Hideo Tomihara | Cihui Zhu | F. Citron | F. Carbone | L. Perelli | Edoardo Del Poggetto | M. Soeung | Hania Khan | Ying-bei Chen | Ruohan Xia | R. G. D. Natale | Alaa M. T. Mohamed | Courtney Le | T. Nguyen | Anh K Lam | Courtney N Le | Virginia Giuliani | Luigi Perelli
[1] A. Krasnitz,et al. Ordered and deterministic cancer genome evolution after p53 loss , 2022, Nature.
[2] Kaitlin J. Flynn,et al. Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity , 2022, Science Translational Medicine.
[3] Jacob D. Jaffe,et al. Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors. , 2022, Cell stem cell.
[4] David R. Jones,et al. Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients , 2021, Cell.
[5] Eiru Kim,et al. Improved analysis of CRISPR fitness screens and reduced off-target effects with the BAGEL2 gene essentiality classifier , 2021, Genome Medicine.
[6] T. Choueiri,et al. Results of a multicenter, phase 2 study of nivolumab and ipilimumab for patients with advanced rare genitourinary malignancies , 2020, Cancer.
[7] T. Bathala,et al. Outcomes of patients with metastatic renal cell carcinoma with sarcomatoid dedifferentiation to immune checkpoint inhibitors. , 2020, Urologic oncology.
[8] Amber C. Donahue,et al. Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial , 2020, Nature Medicine.
[9] Ashton C. Berger,et al. Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma , 2020, Nature Medicine.
[10] I. Wistuba,et al. Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. , 2020, Cancer cell.
[11] Steven L. Chang,et al. Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma , 2020, Nature Communications.
[12] Sebastian Lange,et al. Analysis pipelines for cancer genome sequencing in mice , 2020, Nature Protocols.
[13] J. Espinosa,et al. Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity , 2019, Proceedings of the National Academy of Sciences.
[14] R. Motzer,et al. Towards individualized therapy for metastatic renal cell carcinoma , 2019, Nature Reviews Clinical Oncology.
[15] A. Amon,et al. Context is everything: aneuploidy in cancer , 2019, Nature Reviews Genetics.
[16] T. Margaritis,et al. Tubuloids derived from human adult kidney and urine for personalized disease modeling , 2019, Nature Biotechnology.
[17] Matthew C. Canver,et al. CRISPResso2 provides accurate and rapid genome editing sequence analysis , 2019, Nature Biotechnology.
[18] Shan Jiang,et al. Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors. , 2019, Cell reports.
[19] M. Stratton,et al. Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma , 2018, bioRxiv.
[20] L. Cantley,et al. The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment , 2018, Cell.
[21] Christopher T. Saunders,et al. Strelka2: fast and accurate calling of germline and somatic variants , 2018, Nature Methods.
[22] G. Mayhew,et al. Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal , 2018, Cell.
[23] Ashton C. Berger,et al. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. , 2018, Cancer cell.
[24] Steven J. M. Jones,et al. Oncogenic Signaling Pathways in The Cancer Genome Atlas. , 2018, Cell.
[25] Paul T. Spellman,et al. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma , 2018, Cell reports.
[26] Paul Hoffman,et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.
[27] Mathias J Friedrich,et al. Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes , 2018, Nature.
[28] Samuel F. Bakhoum,et al. Chromosomal instability drives metastasis through a cytosolic DNA response , 2017, Nature.
[29] K. Hess,et al. Outcomes of Patients with Renal Cell Carcinoma and Sarcomatoid Dedifferentiation Treated with Nephrectomy and Systemic Therapies: Comparison between the Cytokine and Targeted Therapy Eras , 2017, The Journal of urology.
[30] Hannah A. Pliner,et al. Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.
[31] Lindsay A. Williams,et al. MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma , 2017, Nature Communications.
[32] L. Chin,et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer , 2017, Nature.
[33] N. Schultz,et al. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets , 2016, Nature Communications.
[34] J. Wargo,et al. Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy , 2016, Cell.
[35] P. Stephens,et al. Genomic Characterization of Renal Cell Carcinoma with Sarcomatoid Dedifferentiation Pinpoints Recurrent Genomic Alterations. , 2016, European urology.
[36] Funda Meric-Bernstam,et al. Punctuated Copy Number Evolution and Clonal Stasis in Triple-Negative Breast Cancer , 2016, Nature Genetics.
[37] V. Seshan,et al. FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing , 2016, Nucleic acids research.
[38] Eric Talevich,et al. CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing , 2016, PLoS Comput. Biol..
[39] Chris Sander,et al. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. , 2016, Cell reports.
[40] U. Harmenberg,et al. Renal cell carcinoma recurrences and metastases in primary non-metastatic patients: a population-based study , 2016, World Journal of Urology.
[41] J. Hsieh,et al. A river model to map convergent cancer evolution and guide therapy in RCC , 2015, Nature Reviews Urology.
[42] Dian Yang,et al. Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing , 2015, Genes & development.
[43] Donavan T. Cheng,et al. Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology. , 2015, The Journal of molecular diagnostics : JMD.
[44] Nathan C. Klapoetke,et al. Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance , 2015, Neuron.
[45] Z. Szallasi,et al. Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data , 2014, Annals of oncology : official journal of the European Society for Medical Oncology.
[46] G. McVean,et al. Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applications , 2014, Nature Genetics.
[47] Renu Malhotra,et al. IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples , 2014, PloS one.
[48] David T. W. Jones,et al. Signatures of mutational processes in human cancer , 2013, Nature.
[49] A. Sivachenko,et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples , 2013, Nature Biotechnology.
[50] Christopher A. Miller,et al. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. , 2012, Genome research.
[51] Yueming Ding,et al. Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn , 2011, Mammalian Genome.
[52] Thomas M. Keane,et al. Sequence-based characterization of structural variation in the mouse genome , 2011, Nature.
[53] G. Getz,et al. GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers , 2011, Genome Biology.
[54] M. DePristo,et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data , 2011, Nature Genetics.
[55] Allan R. Jones,et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain , 2009, Nature Neuroscience.
[56] H. Pickett,et al. Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions , 2009, Nature Structural &Molecular Biology.
[57] Kai Ye,et al. Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads , 2009, Bioinform..
[58] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[59] Cole Trapnell,et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.
[60] Andrew L Kung,et al. Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination. , 2003, Molecular imaging.
[61] M. Busslinger,et al. Nephric lineage specification by Pax2 and Pax8. , 2002, Genes & development.