Improved temperature monitoring and treatment planning for loco-regional hyperthermia treatments of Non-Muscle Invasive Bladder Cancer (NMIBC)

Introduction– Hyperthermia is a cancer treatment that increases the effectiveness of radiotherapy or chemotherapy by heating the tumor area to 41-43°C. Recently, a multi-center phase III randomized clinical trial comparing adjuvant treatment of NMIBC using Mitomycin C with and without loco-regional hyperthermia has started. This invites careful consideration of the bladder as a treatment site. Optimal treatment and quality control requires reliable thermometry and accurate hyperthermia treatment planning. This study aims to improve the current standard in both areas.