Treatment with two diff erent doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma ( BOLT ) : a multicentre , randomised , double-blind phase 2 trial

Mohs Surgery Center, Department of Dermatology, University of Texas MD Anderson Cancer Center, Houston, TX, USA (M R Migden MD); Department of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW, Australia (A Guminski PhD); Department of Dermatology and Allergy, Medizinische Hochschule Hannover, Hannover, Germany (Prof R Gutzmer MD); Department of Medical Oncology, Sint-Augustinus Ziekenhuis, Antwerp, Belgium (L Dirix MD); Division of Medical Oncology, University of Colorado School of Medicine, Aurora, CO, USA (K D Lewis MD); Department of OncoDermatology, Anticancer Institute, Lyon, France (P Combemale MD); Department of Dermatology, Glasgow Royal Infi rmary, Glasgow, UK (R M Herd MD); Department of Cutaneous Oncology, Moffi tt Cancer Center, Tampa, FL, USA (R Kudchadkar MD); Dermatologikum Berlin, Berlin, Germany (Prof U Trefzer MD); Oncology Clinical Development, Novartis Pharma, Basel, Switzerland (S Gogov MD, C Pallaud PhD); Biometrics and Data Management, Oncology Business Unit (T Yi PhD), Oncology Clinical Development (M Mone PhD), and Oncology Global Development (D Sellami MD), Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA; Department of Dermatology and Allergology, University Hospital Jena, Jena, Germany (M Kaatz MD); SRH Wald-Klinikum Gera, Gera, Treatment with two diff erent doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial

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