In vitro and in silico studies of 7′′,8′′-buddlenol D anti-inflammatory lignans from Carallia brachiata as p38 MAP kinase inhibitors

[1]  P. Pancorbo-Hidalgo,et al.  The Role of Antioxidants on Wound Healing: A Review of the Current Evidence , 2021, Journal of clinical medicine.

[2]  Ya-Ping Liu,et al.  Chemical constituents from Melodinus cochinchinensis (Lour.) Merr. and their chemotaxonomic significance , 2021 .

[3]  J. Molphy,et al.  The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans , 2021, Scientific Reports.

[4]  C. Chansriniyom,et al.  S-deoxydihydroglyparvin from Glycosmis parva inhibits lipopolysaccharide induced murine macrophage activation through inactivating p38 mitogen activated protein kinase , 2021, Journal of advanced pharmaceutical technology & research.

[5]  V. Patrone,et al.  Lignans and Gut Microbiota: An Interplay Revealing Potential Health Implications , 2020, Molecules.

[6]  M. Rudrapal,et al.  Antidiabetic activity of Carallia brachiata Lour. leaves hydro-alcoholic extract (HAE) with antioxidant potential in diabetic rats , 2020, Indian Journal of Natural Products and Resources.

[7]  Rahman,et al.  IN VIVO EVALUATION OF ANALGESIC, ANTI-INFLAMMATORY AND ANTI- DIABETIC ACTIVITIES OF METHANOL EXTRACT OF CARALLIA BRACHIATA L. LEAVES , 2020 .

[8]  H. Puthalakath,et al.  Sepsis: Inflammation Is a Necessary Evil , 2019, Front. Cell Dev. Biol..

[9]  Yong-Deok Jeon,et al.  Apoptotic effect of enterodiol, the final metabolite of edible lignans, in colorectal cancer cells. , 2019, Journal of the science of food and agriculture.

[10]  Andreas Eckert,et al.  ProTox-II: a webserver for the prediction of toxicity of chemicals , 2018, Nucleic Acids Res..

[11]  Ling Zhao,et al.  Inflammatory responses and inflammation-associated diseases in organs , 2015, Oncotarget.

[12]  Nam‐Jung Kim,et al.  Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer’s Disease , 2017, Molecules.

[13]  P. Lan,et al.  A New Spiro Compound from Caragana acanthophylla , 2017, Chemistry of Natural Compounds.

[14]  Olivier Michielin,et al.  SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules , 2017, Scientific Reports.

[15]  H. Korashy,et al.  Dexamethasone Attenuates LPS-induced Acute Lung Injury through Inhibition of NF-κB, COX-2, and Pro-inflammatory Mediators , 2016, Immunological investigations.

[16]  Gaozhi Chen,et al.  Curcumin Analog L48H37 Prevents Lipopolysaccharide-Induced TLR4 Signaling Pathway Activation and Sepsis via Targeting MD2 , 2015, The Journal of Pharmacology and Experimental Therapeutics.

[17]  Thomas Sander,et al.  DataWarrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis , 2015, J. Chem. Inf. Model..

[18]  P. Lograsso,et al.  Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles , 2015, Scientific Reports.

[19]  S. Knapp,et al.  A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics , 2014, Nature chemical biology.

[20]  F. Peri,et al.  Toll-like receptor 4 (TLR4) modulation by synthetic and natural compounds: an update. , 2014, Journal of medicinal chemistry.

[21]  D. Brandeis,et al.  A Review of Current Evidence , 2014 .

[22]  S. Turk,et al.  Novel toll-like receptor 4 (TLR4) antagonists identified by structure- and ligand-based virtual screening. , 2013, European journal of medicinal chemistry.

[23]  Soo‐Young Choi,et al.  Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages. , 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[24]  L. Mosyak,et al.  Crystal Structure of a Human IκB Kinase β Asymmetric Dimer , 2013, The Journal of Biological Chemistry.

[25]  J. de Vlieg,et al.  X-ray structure of p38α bound to TAK-715: comparison with three classic inhibitors. , 2012, Acta crystallographica. Section D, Biological crystallography.

[26]  V. Dixit,et al.  Signaling in innate immunity and inflammation. , 2012, Cold Spring Harbor perspectives in biology.

[27]  Keunwan Park,et al.  Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein , 2012, PloS one.

[28]  Sheng Lin,et al.  Lignans and neolignans from Sinocalamus affinis and their absolute configurations. , 2011, Journal of natural products.

[29]  Yue-Hu Wang,et al.  Two dimeric lignans with an unusual α,β-unsaturated ketone motif from Zanthoxylum podocarpum and their inhibitory effects on nitric oxide production. , 2011, Bioorganic & medicinal chemistry letters.

[30]  Qin Liu,et al.  MicroRNA-101 Targets MAPK Phosphatase-1 To Regulate the Activation of MAPKs in Macrophages , 2010, The Journal of Immunology.

[31]  A. Kuglstatter,et al.  X-ray crystal structure of JNK2 complexed with the p38alpha inhibitor BIRB796: insights into the rational design of DFG-out binding MAP kinase inhibitors. , 2010, Bioorganic & medicinal chemistry letters.

[32]  Guangying Chen,et al.  A new flavonol from the stem-bark of Premna fulva , 2010 .

[33]  J. Yadav,et al.  Total synthesis of (+)-pseudohygroline , 2010 .

[34]  B. Krishnaveni,et al.  Wound Healing Activity of Carallia brachiata Bark , 2009, Indian journal of pharmaceutical sciences.

[35]  S. Hong,et al.  A new furofuran lignan from Isodon japonicus , 2009, Archives of pharmacal research.

[36]  Da Yeon Lee,et al.  In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. , 2009, Bioorganic & medicinal chemistry letters.

[37]  Sheng Lin,et al.  Glycosides from the root of Iodes cirrhosa. , 2008, Journal of natural products.

[38]  J. N. Sharma,et al.  Role of nitric oxide in inflammatory diseases , 2007, Inflammopharmacology.

[39]  Hayyoung Lee,et al.  Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran , 2007, Cell.

[40]  C. Abad-Zapatero,et al.  Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. , 2007, Bioorganic & medicinal chemistry letters.

[41]  T. Pakkanen,et al.  Phenolic compounds in silver birch (Betula pendula Roth) wood , 2006 .

[42]  K. Miyake,et al.  Inhibition of homodimerization of Toll-like receptor 4 by curcumin. , 2006, Biochemical pharmacology.

[43]  P. Phuwapraisirisan,et al.  Reactive radical scavenging and xanthine oxidase inhibition of proanthocyanidins from Carallia brachiata , 2006, Phytotherapy research : PTR.

[44]  T. Tanaka,et al.  A new diglycosyl megastigmane from Carallia brachiata. , 2004, Fitoterapia.

[45]  D. Hommes,et al.  Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets , 2003, Gut.

[46]  L. Tong,et al.  Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site , 2002, Nature Structural Biology.

[47]  J. Coleman Nitric oxide in immunity and inflammation. , 2001, International immunopharmacology.

[48]  M. Belvisi,et al.  Role of p38 MAP kinase in LPS‐induced airway inflammation in the rat , 2001, British journal of pharmacology.

[49]  Jiahuai Han,et al.  The p38 signal transduction pathway: activation and function. , 2000, Cellular signalling.

[50]  Lin,et al.  Involvement of p38 mitogen‐activated protein kinase in lipopolysaccharide‐induced iNOS and COX‐2 expression in J774 macrophages , 1999, Immunology.

[51]  J. Frelek,et al.  [Rh2(OCOCF3)4] as an auxiliary chromophore in chiroptical studies on steroidal alcohols , 1999 .

[52]  B. K. English,et al.  Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma. , 1999, The Journal of infectious diseases.

[53]  M. Rawat,et al.  Proanthocyanidins from Prunus armeniaca roots , 1999 .

[54]  K. Wilson,et al.  A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase , 1998, Protein science : a publication of the Protein Society.

[55]  C. Teng,et al.  Bioactive constitutents from the stems of Annona montana. , 1995, Planta medica.

[56]  G. Snatzke,et al.  Circular dichroism, XCIII determination of the absolute configuration of alcohols, olefins, epoxides, and ethers from the CD of their “in situ” complexes with [Rh2(O2CCF3)4]. , 1990 .

[57]  P. Houghton Lignans and neolignans from Buddleja davidii , 1985 .

[58]  K. Johnson An Update. , 1984, Journal of food protection.

[59]  G. Snatzke,et al.  Circular dichroism—XLVII: Influence of substitution pattern on the benzene 1Lb-band Cotton effect , 1972 .

[60]  J. Fitzgerald (+)-Hygroline, the major alkaloid of Carallia brachiata (Rhizophoraceae) , 1965 .