THERAPEUTIC EFFICACY OF VARIOUS INTRAUTERINE DRUGS ON REPEAT BREEDER GIR COWS

The study was planned to investigate the effect of intrauterine antibiotic treatment on conception rate in repeat breeder Gir cows. In all 48 pluriparous Gir cows (36 repeat breeders not conceived even after 3-5 regular quality AIs, and 12 normal cyclic postpartum cows) were assigned into four groups. Repeat breeder cows were treated with either Gentamicin (100 mg) intrauterine (10 ml diluted with 10 ml distilled water) (Group I; n = 12), Enrofloxacin (Enrogyl, 35mg) (Group II; n = 12) or with Cephalexin (Lixen, 4g) (Group III; n = 12) intrauterine while normal cyclic cows served as untreated (non-repeat breeder) Controls (Group IV: n = 12). The cows in oestrus were inseminated with good quality frozenthawed semen by a single technician at least for three cycles post-treatment if not settled. The pregnancy diagnosis was performed at 60 days post insemination in non-return cases. Conception rates were better with Cephalexin at first, second and third services in repeat breeders. The overall pregnancy rates after three services among four groups were 67, 75, 83 & 58%, respectively in Group I, II, III and IV. In conclusion, the pregnancy rates could be improved by treatment with Cephalexin, Enrofloxacin and Gentamicin in repeat breeder Gir cows.