Single-Mode Tapered Vertical SU-8 Waveguide Fabricated by E-Beam Lithography for Analyte Sensing

In this paper, we propose a novel vertical SU-8 waveguide for evanescent analyte sensing. The waveguide is designed to possess a vertical and narrow structure to generate evanescent waves on both sides of the waveguide’s surface, aimed at increasing the sensitivity by enlarging the sensing areas. We performed simulations to monitor the influence of different parameters on the waveguide’s performance, including its height and width. E-beam lithography was used to fabricate the structure, as this one-step direct writing process enables easy, fast, and high-resolution fabrication. Furthermore, it reduces the sidewall roughness and decreases the induced scattering loss, which is a major source of waveguide loss. Couplers were added to improve the coupling efficiency and alignment tolerance, and will contribute to the feasibility of a plug-and-play optical system. Optical measurements show that the transmission loss is 1.03 ± 0.19 dB/cm. The absorption sensitivity was measured to be 4.8 dB per refractive index unit (dB/RIU) for saline solutions with various concentrations.

[1]  Jianyu Tan,et al.  Optical Properties of Sodium Chloride Solution within the Spectral Range from 300 to 2500 nm at Room Temperature , 2015, Applied spectroscopy.

[2]  F. Leonberger,et al.  Integrated optics , 1986, IEEE Journal of Quantum Electronics.

[3]  L. Eldada,et al.  Advances in polymer integrated optics , 2000, IEEE Journal of Selected Topics in Quantum Electronics.

[4]  S. Mukherji,et al.  Simple surface modification techniques for immobilization of biomolecules on SU-8 , 2009, Journal of materials science. Materials in medicine.

[5]  Sunkyu Yu,et al.  Control of Fano asymmetry in plasmon induced transparency and its application to plasmonic waveguide modulator. , 2012, Optics express.

[6]  E. Ollier Optical MEMS devices based on moving waveguides , 2002 .

[7]  Wei Chih Wang,et al.  Micromachined optical waveguide cantilever as a resonant optical scanner , 2002 .

[8]  A. Knights,et al.  Silicon Photonics: An Introduction , 2004 .

[9]  N. Chronis,et al.  Electrothermally activated SU-8 microgripper for single cell manipulation in solution , 2005, Journal of Microelectromechanical Systems.

[10]  Andrew A. Bettiol,et al.  Proton beam writing of low-loss polymer optical waveguides , 2003 .

[11]  O. Mitomi,et al.  Design of a single-mode tapered waveguide for low-loss chip-to-fiber coupling , 1994 .

[12]  Francesco Dell'Olio,et al.  Optical sensing by optimized silicon slot waveguides. , 2007, Optics express.

[13]  Aaron S. Anderson,et al.  Waveguide-Based Biosensors for Pathogen Detection , 2009, Sensors.

[14]  A. Boisen,et al.  Single-Mode Waveguides With SU-8 Polymer Core and Cladding for MOEMS Applications , 2007, Journal of Lightwave Technology.

[15]  S. Mukherji,et al.  SU-8 POLYMER BASED WAVEGUIDE BIOCHEMICAL SENSOR FOR MEDICAL DIAGNOSTIC APPLICATION , 2009 .

[16]  Pasqualina M. Sarro,et al.  Fabrication and characteristics of a PECVD SiC evanescent wave optical sensor , 2008 .

[17]  Stefan Kedenburg,et al.  Linear refractive index and absorption measurements of nonlinear optical liquids in the visible and near-infrared spectral region , 2012 .

[18]  Nicolas Knudde,et al.  Air-Suspended SU-8 Strip Waveguides With High Refractive Index Contrast , 2016, IEEE Photonics Technology Letters.

[19]  Yuexin Yin,et al.  5-Channel Polymer/Silica Hybrid Arrayed Waveguide Grating , 2020, Polymers.

[20]  Cheng Zeng,et al.  High Confinement Factor Ridge Slot Waveguide for Optical Sensing , 2015, IEEE Photonics Technology Letters.

[21]  Stewart E. Miller,et al.  Integrated optics: An introduction , 1969 .

[22]  T. M. Verhaar,et al.  Pattern transfer on a vertical cavity sidewall using SU8 , 2009 .

[23]  A. Prabhakar,et al.  Microfabricated polymer chip with integrated U-bend waveguides for evanescent field absorption based detection. , 2010, Lab on a chip.

[24]  B. Cunningham Label-free optical biosensors: An introduction , 2009 .

[25]  Joseph Zyss,et al.  Single-mode TE00-TM00 optical waveguides on SU-8 polymer , 2004 .