Influence of ESR 1 and FSHB genes on litter size in Czech Large White sows

The effects of the candidate genes for reproduction, the estrogen receptor gene (ESR1) and the folliclestimulating hormone beta subunit gene (FSHB), on the performance of Large White sows in the three different herds have been examined. A total number of 271 sows (in case of the ESR1 gene) and 171 sows (in case of the FSHB gene) were genotyped with PCR-RFLP method and analysed to determine whether polymorphisms of the genes influence the efficiency of Large White sows. The influence of these genes in the first, the first to the fourth and the second to the fourth litters was investigated. To discover the genes ́ associations with reproduction traits, mixed linear models were used. The influence of ESR1 and FSHB genes was not very conclusive in the studied populations. The influence of these genes was different depending on the herd, in which the sows were bred or on the set of analyzed litters.

[1]  J. Wolf,et al.  Impact of the ESR gene on litter size and production traits in Czech Large White pigs. , 2004, Animal genetics.

[2]  V. Matoušek,et al.  Effect of RYR1 and ESR genotypes on the fertility of sows of Large White breed in elite herds , 2003 .

[3]  K. M. Irvin,et al.  Examination of the relationship between the estrogen receptor gene and reproductive traits in swine. , 2002, Journal of animal science.

[4]  D. Pomp,et al.  Candidate gene analysis for loci affecting litter size and ovulation rate in swine. , 2001, Journal of animal science.

[5]  K. Grijspeerdt,et al.  ASSOCIATION STUDY OF AN AVAI AND PVUII POLYMORPHISM AT THE PORCINE ESTROGEN RECEPTOR (ESR) GENE, WITH LITTER SIZE , 1999 .

[6]  J. Krieter,et al.  Influence of the genome region surrounding the estrogen receptor (ESR) gene on litter size in a German Landrace population , 1999 .

[7]  C. Tuggle,et al.  Effect of the estrogen receptor locus on reproduction and production traits in four commercial pig lines. , 1997, Journal of animal science.

[8]  M. Yerle,et al.  PCR amplification and physical localization of the genes for pig FSHB and LHB. , 1995, Cytogenetics and cell genetics.

[9]  L. Alexander,et al.  Mapping the beta subunit of follicle stimulating hormone (FSHB) in the porcine genome. , 1994, Mammalian genome : official journal of the International Mammalian Genome Society.

[10]  G. S. Greenwald,et al.  Hypophysectomy of the cyclic mouse. I. Effects on folliculogenesis, oocyte growth, and follicle-stimulating hormone and human chorionic gonadotropin receptors. , 1993, Biology of reproduction.

[11]  P. Pearson,et al.  PvuII polymorphisms at the porcine oestrogen receptor locus (ESR). , 2009, Animal genetics.