HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains
暂无分享,去创建一个
Hong-Gang Wang | Shao-Cong Sun | T. Loughran | Xin Liu | Yoshinori Takahashi | Hua Cheng | Tongwei Ren
[1] Z. Klase,et al. The Cellular Autophagy Pathway Modulates Human T-Cell Leukemia Virus Type 1 Replication , 2012, Journal of Virology.
[2] Thomas P. Loughran,et al. HTLV-2 Tax Immortalizes Human CD4+ Memory T Lymphocytes by Oncogenic Activation and Dysregulation of Autophagy* , 2012, The Journal of Biological Chemistry.
[3] You-Wen He,et al. Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB. , 2012, Immunity.
[4] L. Galluzzi,et al. Direct molecular interactions between Beclin 1 and the canonical NFκB activation pathway , 2012, Autophagy.
[5] L. Covey,et al. c-Rel Deficiency Increases Caspase-4 Expression and Leads to ER Stress and Necrosis in EBV-Transformed Cells , 2011, PloS one.
[6] J. Guan,et al. Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis. , 2011, Genes & development.
[7] G. Semenza,et al. Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells , 2007, The Biochemical journal.
[8] S. Ryter,et al. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema , 2010, Proceedings of the National Academy of Sciences.
[9] KyungMann Kim,et al. Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF. , 2010, The Journal of investigative dermatology.
[10] H. Wen,et al. Enhancement of Autophagy during Lytic Replication by the Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Activator , 2010, Journal of Virology.
[11] D. Ann,et al. The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication , 2010, Proceedings of the National Academy of Sciences.
[12] L. Zitvogel,et al. The IKK complex contributes to the induction of autophagy , 2010, The EMBO journal.
[13] Lixin Wei,et al. Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells , 2009, Autophagy.
[14] F. Chisari,et al. Autophagy proteins promote hepatitis C virus replication , 2009, Autophagy.
[15] I. Nabi,et al. Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling , 2009, PloS one.
[16] N. Enomoto,et al. Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy , 2009, Journal of Gastroenterology.
[17] F. Chisari,et al. The autophagy machinery is required to initiate hepatitis C virus replication , 2009, Proceedings of the National Academy of Sciences.
[18] Kristin L. Hazelwood,et al. Far-red fluorescent tags for protein imaging in living tissues. , 2009, The Biochemical journal.
[19] Hua Cheng,et al. HTLV-1 Tax Is a Critical Lipid Raft Modulator That Hijacks IκB Kinases to the Microdomains for Persistent Activation of NF-κB* , 2009, Journal of Biological Chemistry.
[20] David J. Chen,et al. DNA-PKcs Is Required for Activation of Innate Immunity by Immunostimulatory DNA , 2009, Cell.
[21] Mu-jun Zhao,et al. Hepatitis B virus X protein sensitizes cells to starvation‐induced autophagy via up‐regulation of beclin 1 expression , 2009, Hepatology.
[22] B. Sugden,et al. The latent membrane protein 1 oncogene modifies B-cell physiology by regulating autophagy , 2008, Oncogene.
[23] Robert E Campbell,et al. Hue-shifted monomeric variants of Clavularia cyan fluorescent protein: identification of the molecular determinants of color and applications in fluorescence imaging , 2008 .
[24] J. J. Mul,et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis , 2007, Nature Cell Biology.
[25] G. Xiao,et al. Targeting Autophagic Regulation of NF-kappaB in HTLV-I Transformed Cells by Geldanamycin: Implications for Therapeutic Interventions , 2007, Autophagy.
[26] E. White,et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. , 2007, Genes & development.
[27] J. Cleveland,et al. Modulating Autophagy for Therapeutic Benefit , 2007, Autophagy.
[28] M. Berger,et al. DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells , 2007, Cell Death and Differentiation.
[29] E. Harhaj,et al. Activation of NF-κB by the Human T Cell Leukemia Virus Type I Tax Oncoprotein Is Associated with Ubiquitin-dependent Relocalization of IκB Kinase* , 2006, Journal of Biological Chemistry.
[30] Simon A. Jones,et al. Human T‐cell leukemia virus type‐I Tax induces expression of interleukin‐6 receptor (IL‐6R): Shedding of soluble IL‐6R and activation of STAT3 signaling , 2006, International journal of cancer.
[31] Kevin Bray,et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. , 2006, Cancer cell.
[32] C. Cheng‐Mayer,et al. Molecular Mechanism of hTid-1, the Human Homolog of Drosophila Tumor Suppressor l(2)Tid, in the Regulation of NF-κB Activity and Suppression of Tumor Growth , 2005, Molecular and Cellular Biology.
[33] T. P. Neufeld,et al. Role and regulation of starvation-induced autophagy in the Drosophila fat body. , 2004, Developmental cell.
[34] S. Furuta,et al. Ras is involved in the negative control of autophagy through the class I PI3-kinase , 2004, Oncogene.
[35] Govind Bhagat,et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. , 2003, The Journal of clinical investigation.
[36] M. Xie,et al. Persistent Activation of NF-κB by the Tax Transforming Protein Involves Chronic Phosphorylation of IκB Kinase Subunits IKKβ and IKKγ* , 2001, The Journal of Biological Chemistry.
[37] M. Yamakuchi,et al. Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax , 2001, Oncogene.
[38] M. Karin,et al. IKKβ Is Essential for Protecting T Cells from TNFα-Induced Apoptosis , 2001 .
[39] David J. Chen,et al. RETRACTED: DNA-PKcs Is Required for Activation of Innate Immunity by Immunostimulatory DNA , 2000, Cell.
[40] V. Godfrey,et al. Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. , 2000, Molecular cell.
[41] P. Codogno,et al. Distinct Classes of Phosphatidylinositol 3′-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells* , 2000, The Journal of Biological Chemistry.
[42] H. Hibshoosh,et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1 , 1999, Nature.
[43] K. N. Pennington,et al. Protein Kinase C and Calcineurin Synergize to Activate IκB Kinase and NF-κB in T Lymphocytes* , 1999, The Journal of Biological Chemistry.
[44] E. Harhaj,et al. IKKγ Serves as a Docking Subunit of the IκB Kinase (IKK) and Mediates Interaction of IKK with the Human T-cell Leukemia Virus Tax Protein* , 1999, The Journal of Biological Chemistry.
[45] D. Vestweber,et al. Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines. , 1999, Histochemistry and cell biology.
[46] K. Jeang,et al. Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB , 1999, The Journal of Biological Chemistry.
[47] T. Deerinck,et al. The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis , 1999, The Journal of experimental medicine.
[48] D. Ballard,et al. IKKγ Mediates the Interaction of Cellular IκB Kinases with the Tax Transforming Protein of Human T Cell Leukemia Virus Type 1* , 1999, The Journal of Biological Chemistry.
[49] M. Kannagi,et al. Human T-cell leukemia virus type 1 Tax protein induces the expression of STAT1 and STAT5 genes in T-cells , 1999, Oncogene.
[50] Inder M. Verma,et al. Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene , 1999 .
[51] E. Zandi,et al. IKK-γ is an essential regulatory subunit of the IκB kinase complex , 1998, Nature.
[52] D. Ballard,et al. The Tax Oncoprotein of Human T-cell Leukemia Virus Type 1 Associates with and Persistently Activates IκB Kinases Containing IKKα and IKKβ* , 1998, The Journal of Biological Chemistry.
[53] L. O’Neill,et al. Signal transduction pathways activated by the IL‐1 receptor family: ancient signaling machinery in mammals, insects, and plants , 1998, Journal of leukocyte biology.
[54] Matthias Mann,et al. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation , 1997 .
[55] E. Zandi,et al. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. , 1997, Cell.
[56] E. Zandi,et al. The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation , 1997, Cell.
[57] P. Verkade,et al. Lipid microdomains and membrane trafficking in mammalian cells , 1997, Histochemistry and Cell Biology.
[58] N. Mori,et al. Production of interleukin 8 in adult T-cell leukemia cells: possible transactivation of the interleukin 8 gene by human T-cell leukemia virus type I tax. , 1995, Cancer research.
[59] N. Adya,et al. Distinct regions in human T-cell lymphotropic virus type I tax mediate interactions with activator protein CREB and basal transcription factors , 1995, Journal of virology.
[60] G. Baier,et al. Activation of phosphatidylinositol‐3‐kinase in Jurkat T cells depends on the presence of the p56lck tyrosine kinase , 1994, European journal of immunology.
[61] M. Hatanaka. [Transformation by the tax gene of HTLV-1]. , 1992, Uirusu.
[62] W. Greene,et al. Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes. , 1990, Genes & development.
[63] T. Schulz,et al. Transforming properties of the HTLV-I tax gene. , 1990, Cancer cells.
[64] W. Greene,et al. Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen , 1984, The Journal of experimental medicine.
[65] J. Yodoi,et al. Failure of regulation of Tac antigen/TCGF receptor on adult T-cell leukemia cells by anti-Tac monoclonal antibody. , 1983, Blood.
[66] P. Baudhuin. [Lysosomes and cellular autophagy]. , 1966, Bruxelles medical.
[67] A. Omodeizorini. [CONSIDERATIONS ON PRIMARY CARCINOMATOUS CAVERNS OF THE LUNG. POSSIBILITY OF THE INTERVENTION OF A PHENOMENON OF "AUTOPHAGIA OF THE NEOPLASTIC CELLS"]. , 1964, La Riforma medica.
[68] E. White,et al. Assessing metabolic stress and autophagy status in epithelial tumors. , 2009, Methods in enzymology.
[69] E. Harhaj,et al. Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase. , 2007, The Journal of biological chemistry.
[70] M. Xie,et al. Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma. , 2001, The Journal of biological chemistry.
[71] M. Karin,et al. IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosis. , 2001, Immunity.
[72] I. Verma,et al. Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. , 1999, Science.
[73] J. Yang,et al. IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1. , 1999, The Journal of biological chemistry.
[74] E. Harhaj,et al. IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein. , 1999, The Journal of biological chemistry.
[75] K. Jeang,et al. Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma. , 1999, The Journal of biological chemistry.
[76] D. Ballard,et al. The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta. , 1998, The Journal of biological chemistry.
[77] E. Zandi,et al. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. , 1998, Nature.
[78] A. Meijer,et al. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. , 1997, European journal of biochemistry.
[79] D B Young,et al. IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. , 1997, Science.
[80] A. Omodei Zorini. [Considerations on primary carcinomatous caverns of the lung. Possibility of the intervention of a phenomenon of "autophagy of the neoplastic cells"]. , 1965, Lotta contro la tubercolosi.