Methods in heart rate variability analysis: which tachogram should we choose?

We investigated the practical impact of the representation of the cardiac rhythm--the cardiotachogram--on two elementary spectral indexes in heart rate variability analysis: the low-frequency (0.07-0.14 Hz) and high-frequency (0.14-0.40 Hz) powers. Five commonly used tachograms (inter-beat interval function/series, counts, instantaneous heart rate function/series) were compared. Measurements were done on seven volunteers in the supine and standing positions. Ratios, and their deviations from 100%, of alternative power values were calculated. Mean low-frequency and high-frequency ratio deviations ranged from 0 to 5% and from 6 to 37%. The spectrum of counts yielded on average more (15-37%) high-frequency power. Spectra were incomparable without normalization of the tachogram with respect to heart rate. In conclusion, (i) the choice of a particular spectrum may lead to differing conclusions on the vagal contribution to heart rate variability and (ii) inconclusive results from studies using different tachogram variants can partly be due to the omission of normalization.

[1]  P. Reddy,et al.  Respiratory sinus arrhythmia in the denervated human heart. , 1989, Journal of applied physiology.

[2]  R Arzbaecher,et al.  A pill electrode for the study of cardiac arrhythmia. , 1978, Medical instrumentation.

[3]  A. Malliani,et al.  Continuous 24-hour assessment of the neural regulation of systemic arterial pressure and RR variabilities in ambulant subjects. , 1990, Circulation.

[4]  J. Miller,et al.  Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. , 1987, The American journal of cardiology.

[5]  M. Turiel,et al.  Power Spectral Analysis of Heart Rate and Arterial Pressure Variabilities as a Marker of Sympatho‐Vagal Interaction in Man and Conscious Dog , 1986, Circulation research.

[6]  J. Hayano,et al.  Diurnal variations in vagal and sympathetic cardiac control. , 1990, The American journal of physiology.

[7]  J. Bendat,et al.  Random Data: Analysis and Measurement Procedures , 1971 .

[8]  W. C. Randall,et al.  SA nodal parasympathectomy delineates autonomic control of heart rate power spectrum. , 1991, The American journal of physiology.

[9]  R J Cohen,et al.  Comparison of time- and frequency domain-based measures of cardiac parasympathetic activity in Holter recordings after myocardial infarction. , 1989, The American journal of cardiology.

[10]  G. Moody,et al.  Spectral characteristics of heart rate variability before and during postural tilt. Relations to aging and risk of syncope. , 1990, Circulation.

[11]  R J Cohen,et al.  Assessment of autonomic regulation in chronic congestive heart failure by heart rate spectral analysis. , 1988, The American journal of cardiology.

[12]  J. Strackee,et al.  Comparing Spectra of a Series of Point Events Particularly for Heart Rate Variability Data , 1984, IEEE Transactions on Biomedical Engineering.

[13]  D. Adam,et al.  Assessment of autonomic function in humans by heart rate spectral analysis. , 1985, The American journal of physiology.

[14]  Otto Rompelman,et al.  The Measurement of Heart Rate Variability Spectra with the Help of a Personal Computer , 1982, IEEE Transactions on Biomedical Engineering.

[15]  K H Wesseling,et al.  Non-invasive continuous finger blood pressure measurement during orthostatic stress compared to intra-arterial pressure. , 1990, Cardiovascular research.

[16]  J. Hayano,et al.  Accuracy of assessment of cardiac vagal tone by heart rate variability in normal subjects. , 1991, The American journal of cardiology.

[17]  R. Cohen,et al.  Hemodynamic regulation: investigation by spectral analysis. , 1985, The American journal of physiology.

[18]  D. Singer,et al.  Reproducibility and relation to mean heart rate of heart rate variability in normal subjects and in patients with congestive heart failure secondary to coronary artery disease. , 1991, The American journal of cardiology.

[19]  Glenn A. Myers,et al.  Power Spectral Analysis of Heart Rate Varability in Sudden Cardiac Death: Comparison to Other Methods , 1986, IEEE Transactions on Biomedical Engineering.

[20]  R. Hughson,et al.  Autonomic control of heart rate during exercise studied by heart rate variability spectral analysis. , 1991, Journal of applied physiology.

[21]  W E Boden,et al.  Effect of passive tilt on sympathetic and parasympathetic components of heart rate variability in normal subjects. , 1989, The American journal of cardiology.

[22]  J. Saul,et al.  Modulation of cardiac autonomic activity during and immediately after exercise. , 1989, The American journal of physiology.

[23]  R. B. Pinter,et al.  Pulse modulation in physiological systems, phenomenological aspects. , 1961, IRE transactions on bio-medical electronics.

[24]  A. J. Dunning,et al.  Mechanisms of initial heart rate response to postural change. , 1982, The American journal of physiology.

[25]  P. Castiglioni,et al.  24 h sequential spectral analysis of arterial blood pressure and pulse interval in free-moving subjects , 1989, IEEE Transactions on Biomedical Engineering.

[26]  J. Hayano,et al.  Decreased magnitude of heart rate spectral components in coronary artery disease. Its relation to angiographic severity. , 1990, Circulation.

[27]  R. Cohen,et al.  An Efficient Algorithm for Spectral Analysis of Heart Rate Variability , 1986, IEEE Transactions on Biomedical Engineering.