Kalman smoother based time-varying spectrum estimation of EEG during single agent propofol anesthesia

A time-varying parametric spectrum estimation method for analyzing EEG dynamics is presented. EEG signals are first modeled as a time-varying auto-regressive stochastic process and the model parameters are estimated recursively with a Kalman smoother algorithm. Time-varying spectrum estimates are then obtained from the estimated parameters. The proposed method was applied to measurements collected during low dose propofol anesthesia. The method was able to detect changes of event related (de)synchronization type elicited by verbal command.

[1]  E. John,et al.  Changes in cortical electrical activity during induction of anaesthesia with thiopental/fentanyl and tracheal intubation: a quantitative electroencephalographic analysis. , 2004, British journal of anaesthesia.

[2]  A. Yli-Hankala,et al.  Increase in high frequency EEG activity explains the poor performance of EEG spectral entropy monitor during S-ketamine anesthesia , 2006, Clinical Neurophysiology.

[3]  G Stockmanns,et al.  Wavelet Analysis of Middle Latency Auditory Evoked Responses: Calculation of an Index for Detection of Awareness during Propofol Administration , 2001, Anesthesiology.

[4]  Nitish V. Thakor,et al.  Monotonicity of approximate entropy during transition from awareness to unresponsiveness due to propofol anesthetic induction , 2006, IEEE Transactions on Biomedical Engineering.

[5]  Eberhard Kochs,et al.  Surgical Stimulation Induces Changes in Brain Electrical Activity during Isoflurane/Nitrous Oxide Anesthesia: A Topographic Electroencephalographic Analysis , 1994, Anesthesiology.

[6]  M. Särkelä,et al.  Bispectral Index, Entropy, and Quantitative Electroencephalogram during Single-agent Xenon Anesthesia , 2008, Anesthesiology.

[7]  Fernando Lopes da Silva,et al.  Comprar Niedermeyer's Electroencephalography, 6/e (Basic Principles, Clinical Applications, and Related Fields ) | Fernando Lopes Da Silva | 9780781789424 | Lippincott Williams & Wilkins , 2010 .

[8]  Mika P. Tarvainen,et al.  Estimation of nonstationary EEG with Kalman smoother approach: an application to event-related synchronization (ERS) , 2004, IEEE Transactions on Biomedical Engineering.

[9]  M. Tarvainen,et al.  Time-varying analysis of heart rate variability signals with a Kalman smoother algorithm , 2006, Physiological measurement.

[10]  L. Jameson,et al.  Using EEG to monitor anesthesia drug effects during surgery , 2006, Journal of Clinical Monitoring and Computing.

[11]  G B Boylan,et al.  Behaviour of spectral entropy, spectral edge frequency 90%, and alpha and beta power parameters during low-dose propofol infusion. , 2008, British journal of anaesthesia.

[12]  A. Walker Electroencephalography, Basic Principles, Clinical Applications and Related Fields , 1982 .

[13]  G Schwarz,et al.  Is there paradoxical arousal reaction in the EEG subdelta range in patients during anesthesia? , 1999, Journal of neurosurgical anesthesiology.

[14]  M. Koskinen,et al.  Evoked EEG patterns during burst suppression with propofol. , 2004, British journal of anaesthesia.