Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.
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S. Gygi | J. Harper | Mark P. Jedrychowski | S. Beausoleil | D. Finley | A. Ordureau | M. Isasa | Miguel A. Prado | Christopher M. Rose | J. Harper
[1] Marco Y. Hein,et al. The Perseus computational platform for comprehensive analysis of (prote)omics data , 2016, Nature Methods.
[2] Sebastian A. Wagner,et al. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria , 2016, Proceedings of the National Academy of Sciences.
[3] Keiji Tanaka,et al. The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation , 2016, EMBO reports.
[4] J. Morrow,et al. Targeting ubiquitination for cancer therapies. , 2015, Future medicinal chemistry.
[5] S. Gygi,et al. Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains. , 2015, Journal of proteome research.
[6] J. Harper,et al. The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy. , 2015, Molecular cell.
[7] Sean J Humphrey,et al. High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics , 2015, Nature Biotechnology.
[8] J. Burman,et al. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy , 2015, Nature.
[9] P. Domingues,et al. The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors , 2015, Scientific Reports.
[10] Meaghan Morris,et al. Tau post-translational modifications in wildtype and human amyloid precursor protein transgenic mice , 2015, Nature Neuroscience.
[11] S. Gygi,et al. Comprehensive Temporal Protein Dynamics during the Diauxic Shift in Saccharomyces cerevisiae , 2015, Molecular & Cellular Proteomics.
[12] Donald S Kirkpatrick,et al. Immunoaffinity enrichment coupled to quantitative mass spectrometry reveals ubiquitin-mediated signaling events. , 2015, Journal of molecular biology.
[13] J Wade Harper,et al. Quantifying ubiquitin signaling. , 2015, Molecular cell.
[14] J. Harper,et al. Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response , 2015, Proceedings of the National Academy of Sciences.
[15] Yong Tae Kwon,et al. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies , 2015, Experimental & Molecular Medicine.
[16] Christine Yu,et al. USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria , 2015, Nature Cell Biology.
[17] R. Youle,et al. The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease , 2015, Neuron.
[18] S. Gygi,et al. Evaluating Multiplexed Quantitative Phosphopeptide Analysis on a Hybrid Quadrupole Mass Filter/Linear Ion Trap/Orbitrap Mass Spectrometer , 2014, Analytical chemistry.
[19] S. Gygi,et al. Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. , 2014, Molecular cell.
[20] Ivan Dikic,et al. Ubiquitination in disease pathogenesis and treatment , 2014, Nature Medicine.
[21] N. Donato,et al. Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway , 2014, Oncotarget.
[22] Edward L. Huttlin,et al. MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes , 2014, Analytical chemistry.
[23] D. Kirkpatrick,et al. The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy , 2014, Nature.
[24] R. Mallampalli,et al. Emerging therapies targeting the ubiquitin proteasome system in cancer. , 2014, The Journal of clinical investigation.
[25] M. Mann,et al. In-Vivo Quantitative Proteomics Reveals a Key Contribution of Post-Transcriptional Mechanisms to the Circadian Regulation of Liver Metabolism , 2014, PLoS genetics.
[26] S. Carr,et al. Large-scale identification of ubiquitination sites by mass spectrometry , 2013, Nature Protocols.
[27] Steven P. Gygi,et al. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization , 2013, Nature.
[28] D R Mani,et al. Refined Preparation and Use of Anti-diglycine Remnant (K-ε-GG) Antibody Enables Routine Quantification of 10,000s of Ubiquitination Sites in Single Proteomics Experiments* , 2012, Molecular & Cellular Proteomics.
[29] Yanji Xu,et al. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. , 2012, Journal of proteome research.
[30] Edward L. Huttlin,et al. Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses. , 2012, Analytical chemistry.
[31] M. Bantscheff,et al. High-resolution enabled TMT 8-plexing. , 2012, Analytical chemistry.
[32] M. Rapé,et al. The Ubiquitin Code , 2012, Annual review of biochemistry.
[33] R. Youle,et al. Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. , 2012, Developmental cell.
[34] Edward L. Huttlin,et al. Systematic and quantitative assessment of the ubiquitin-modified proteome. , 2011, Molecular cell.
[35] N. Mizushima,et al. Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane*♦ , 2011, The Journal of Biological Chemistry.
[36] John Rush,et al. Polyubiquitin Linkage Profiles in Three Models of Proteolytic Stress Suggest the Etiology of Alzheimer Disease* , 2011, The Journal of Biological Chemistry.
[37] R. Youle,et al. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin , 2010, The Journal of cell biology.
[38] Edward L. Huttlin,et al. A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression , 2010, Cell.
[39] S. Gygi,et al. Defining the Human Deubiquitinating Enzyme Interaction Landscape , 2009, Cell.
[40] D. Finley,et al. Recognition and processing of ubiquitin-protein conjugates by the proteasome. , 2009, Annual review of biochemistry.
[41] H. Clevers,et al. Proteome changes induced by knock-down of the deubiquitylating enzyme HAUSP/USP7. , 2007, Journal of proteome research.
[42] Steven P Gygi,et al. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry , 2007, Nature Methods.
[43] Steven P Gygi,et al. A proteomics approach to understanding protein ubiquitination , 2003, Nature Biotechnology.
[44] M. Mann,et al. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. , 2003, Analytical chemistry.
[45] J. Yates,et al. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database , 1994, Journal of the American Society for Mass Spectrometry.
[46] S. Gygi,et al. ms3 eliminates ratio distortion in isobaric multiplexed quantitative , 2011 .