Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone
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H. Katus | Dierk Thomas | E. Zitron | C. Kiesecker | E. Scholz | Sonja Lück | R. Bloehs | S. Kathöfer | J. Kiehn | V. Kreye | W. Schoels | C. Karle | Claudia Kiesecker | Ramona Bloehs
[1] H. Katus,et al. Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine , 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.
[2] J. Hancox,et al. Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652 , 2003, British journal of pharmacology.
[3] J. Mitcheson. Drug binding to HERG channels: evidence for a ‘non‐aromatic’ binding site for fluvoxamine , 2003, British journal of pharmacology.
[4] W. Alvarez,et al. Safety of Antidepressant Drugs in the Patient with Cardiac Disease: A Review of the Literature , 2003, Pharmacotherapy.
[5] Michael C Sanguinetti,et al. Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain. , 2003, Molecular pharmacology.
[6] A. Camm,et al. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. , 2003, Cardiovascular research.
[7] D. Nutt,et al. Psychotropic Drugs, Cardiac Arrhythmia, and Sudden Death , 2003, Journal of clinical psychopharmacology.
[8] M. Sanguinetti,et al. Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[9] Jules C Hancox,et al. Troubleshooting problems with in vitro screening of drugs for QT interval prolongation using HERG K+ channels expressed in mammalian cell lines and Xenopus oocytes. , 2002, Journal of pharmacological and toxicological methods.
[10] Dierk Thomas,et al. Bertosamil blocks HERG potassium channels in their open and inactivated states , 2002, British journal of pharmacology.
[11] D. Vitezić,et al. Erectile dysfunction: oral pharmacotherapy options. , 2002, International journal of clinical pharmacology and therapeutics.
[12] Michael C Sanguinetti,et al. Molecular Determinants of Voltage-dependent Human Ether-a-Go-Go Related Gene (HERG) K+ Channel Block* , 2002, The Journal of Biological Chemistry.
[13] P. Goodnick,et al. Psychotropic drugs and the ECG: focus on the QTc interval , 2002, Expert opinion on pharmacotherapy.
[14] Jules C Hancox,et al. Inhibitory actions of the selective serotonin re‐uptake inhibitor citalopram on HERG and ventricular L‐type calcium currents , 2002, FEBS letters.
[15] Dierk Thomas,et al. The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels. , 2002, The Journal of pharmacology and experimental therapeutics.
[16] A. de Meester,et al. FATAL OVERDOSE WITH TRAZODONE : CASE REPORT AND LITERATURE REVIEW , 2001, Acta clinica Belgica.
[17] A. Brown,et al. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872. , 2001, The Journal of pharmacology and experimental therapeutics.
[18] Jun Chen,et al. A structural basis for drug-induced long QT syndrome. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[19] W. Ho,et al. Blockade of the HERG human cardiac K+ channel by the antidepressant drug amitriptyline , 2000, British journal of pharmacology.
[20] John S. Mitcheson,et al. Trapping of a Methanesulfonanilide by Closure of the Herg Potassium Channel Activation Gate , 2000, The Journal of general physiology.
[21] J. Hancox,et al. Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline , 1999, British journal of pharmacology.
[22] A. Brown,et al. Pathways of HERG inactivation. , 1999, American journal of physiology. Heart and circulatory physiology.
[23] J. Levenson. Prolonged QT interval after trazodone overdose. , 1999, The American journal of psychiatry.
[24] M. Keating,et al. MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia , 1999, Cell.
[25] W. Kübler,et al. Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels , 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.
[26] J. Sánchez-Chapula,et al. Mechanism of block of cardiac transient outward K+ current (I(to)) by antidepressant drugs. , 1998, Journal of cardiovascular pharmacology.
[27] Devane Cl. Differential pharmacology of newer antidepressants. , 1998 .
[28] E. Speckmann,et al. Follicular Tissues Reduce Drug Effects on Ion Channels in Oocytes of Xenopus laevis , 1997, The European journal of neuroscience.
[29] M. Sanguinetti,et al. Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides. , 1996, Circulation research.
[30] Gary Yellen,et al. The inward rectification mechanism of the HERG cardiac potassium channel , 1996, Nature.
[31] M. Sanguinetti,et al. A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel , 1995, Cell.
[32] J. Chant,et al. GTPase cascades choreographing cellular behavior: Movement, morphogenesis, and more , 1995, Cell.
[33] D. McTavish,et al. Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders. , 1994, Drugs & aging.
[34] Mark E. Anderson,et al. Cardiac ion channels. , 2002, Annual review of physiology.
[35] J. Feighner. Mechanism of action of antidepressant medications. , 1999, The Journal of clinical psychiatry.