Role of growth factors and the wound healing response in age-related macular degeneration

[1]  E. Scott,et al.  The role of adult bone marrow-derived stem cells in choroidal neovascularization. , 2003, Investigative ophthalmology & visual science.

[2]  Eiji Sakurai,et al.  An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice , 2003, Nature Medicine.

[3]  J. Meurs,et al.  Autologous retinal pigment epithelium and choroid translocation in patients with exudative age-related macular degeneration: short-term follow-up , 2003 .

[4]  D. Hinton,et al.  A role for connective tissue growth factor in the pathogenesis of choroidal neovascularization. , 2003, Archives of ophthalmology.

[5]  G. Thurston Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis , 2003, Cell and Tissue Research.

[6]  J. Ambati,et al.  Macrophage depletion inhibits experimental choroidal neovascularization. , 2003, Investigative ophthalmology & visual science.

[7]  J. Rakic,et al.  Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization. , 2003, Investigative ophthalmology & visual science.

[8]  S. Werner,et al.  Regulation of wound healing by growth factors and cytokines. , 2003, Physiological reviews.

[9]  G. Arden,et al.  Differential effects of light and alcohol on the electro-oculographic responses of patients with age-related macular disease. , 2003, Investigative ophthalmology & visual science.

[10]  Lois E. H. Smith,et al.  Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity. , 2003, The Journal of clinical investigation.

[11]  A. Bird,et al.  Towards an understanding of age-related macular disease , 2003, Eye.

[12]  John I. Loewenstein,et al.  Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration: phase II study results. , 2003, Ophthalmology.

[13]  I. Morita,et al.  Vascular endothelial growth factor upregulates pigment epithelium-derived factor expression via VEGFR-1 in human retinal pigment epithelial cells. , 2003, Biochemical and biophysical research communications.

[14]  G. Vrensen,et al.  Vascular endothelial growth factors and angiogenesis in eye disease , 2003, Progress in Retinal and Eye Research.

[15]  A. Luttun,et al.  Placental Growth Factor (PlGF) and Its Receptor Flt‐1 (VEGFR‐1) , 2002 .

[16]  I. Constable,et al.  Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model. , 2002, The American journal of pathology.

[17]  O. Volpert,et al.  Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. , 2002, American journal of ophthalmology.

[18]  E. Barrón,et al.  Novel growth factors involved in the pathogenesis of proliferative vitreoretinopathy , 2002, Eye.

[19]  Y. Ogura,et al.  Vascular endothelial growth factor family and receptor expression in human choroidal neovascular membranes. , 2002, Microvascular research.

[20]  Joan W. Miller,et al.  Expression of pigment epithelium-derived factor in experimental choroidal neovascularization. , 2002, Investigative ophthalmology & visual science.

[21]  H. Grossniklaus,et al.  Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization. , 2002, Molecular vision.

[22]  Joyce Tombran-Tink,et al.  Expression of pigment epithelium-derived factor in normal adult rat eye and experimental choroidal neovascularization. , 2002, Investigative ophthalmology & visual science.

[23]  Joan W. Miller,et al.  Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment. , 2002, Archives of ophthalmology.

[24]  P. Carmeliet,et al.  Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders. , 2002, Seminars in cell & developmental biology.

[25]  P. Overbeek,et al.  Regulation of choroid development by the retinal pigment epithelium. , 2001, Molecular vision.

[26]  I. Morita,et al.  Novel mechanism for age‐related macular degeneration: An equilibrium shift between the angiogenesis factors VEGF and PEDF , 2001, Journal of cellular physiology.

[27]  R. Bucala,et al.  Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites1 , 2001, The Journal of Immunology.

[28]  J. Lim,et al.  Angiopoietin-1 upregulation by vascular endothelial growth factor in human retinal pigment epithelial cells. , 2001, Investigative ophthalmology & visual science.

[29]  M. Gillies,et al.  Immunological and Aetiological Aspects of Macular Degeneration , 2001, Progress in Retinal and Eye Research.

[30]  R. D'Amato,et al.  Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium. , 2001, The American journal of pathology.

[31]  A. Iannaccone,et al.  Pigment Epithelium-Derived Factor Supports Normal Development of Photoreceptor Neurons and Opsin Expression after Retinal Pigment Epithelium Removal , 2000, The Journal of Neuroscience.

[32]  M. Boulton,et al.  The role of oxidative stress in the pathogenesis of age-related macular degeneration. , 2000, Survey of ophthalmology.

[33]  P. Campochiaro,et al.  Retinal and choroidal neovascularization , 2000, Journal of cellular physiology.

[34]  I J Constable,et al.  Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization. , 2000, The American journal of pathology.

[35]  J. Zhao,et al.  Regulation effect of vascular endothelial growth factor on human fetal choroid vascularization. , 2000, Yan ke xue bao = Eye science.

[36]  K. Bartz-Schmidt,et al.  Clinicopathological correlation in exudative age related macular degeneration: histological differentiation between classic and occult choroidal neovascularisation , 2000, The British journal of ophthalmology.

[37]  P. Campochiaro,et al.  Bone morphogenetic proteins-2 and -4: negative growth regulators in adult retinal pigmented epithelium. , 2000, Investigative ophthalmology & visual science.

[38]  J. Grunwald,et al.  Changes in Choriocapillaris and Retinal Pigment Epithelium ( RPE ) in Age-Related Macular Degeneration , 1999 .

[39]  A Kijlstra,et al.  Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation. , 1999, The American journal of pathology.

[40]  H. Takagi,et al.  Expressions of Angiopoietins and Tie2 in Human Choroidal Neovascular Membranes , 2022 .

[41]  T. Matsumura,et al.  Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo. , 1999, Journal of biochemistry.

[42]  H. Kaplan,et al.  Fas ligand (CD95 ligand) controls angiogenesis beneath the retina , 1999, Nature Medicine.

[43]  T. Otsuji,et al.  Expression of vascular endothelial growth factor and its receptor (KDR/flk-1) mRNA in experimental choroidal neovascularization. , 1999, Current eye research.

[44]  H. Grossniklaus,et al.  Histopathologic and ultrastructural findings of surgically excised choroidal neovascularization. Submacular Surgery Trials Research Group. , 1998, Archives of ophthalmology.

[45]  P. Campochiaro,et al.  A splice variant of trkB and brain-derived neurotrophic factor are co-expressed in retinal pigmented epithelial cells and promote differentiated characteristics , 1998, Brain Research.

[46]  G. Breier,et al.  Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In Vitro , 1998, The Journal of cell biology.

[47]  W. Li,et al.  Extracellular matrix of retinal pigment epithelium regulates choriocapillaris endothelial survival in vitro. , 1997, Experimental eye research.

[48]  Harold E. Dvorak,et al.  Angiogenesis: a Dynamic Balance of Stimulators and Inhibitors , 1997, Thrombosis and Haemostasis.

[49]  N. Yoshimura,et al.  Expression of neurotrophic factors in cultured human retinal pigment epithelial cells. , 1997, Current eye research.

[50]  P. D. de Jong,et al.  Increased expression of angiogenic growth factors in age-related maculopathy , 1997, The British journal of ophthalmology.

[51]  S. Seregard,et al.  Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor. , 1996, Investigative ophthalmology & visual science.

[52]  D. Hinton,et al.  Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. , 1996, Investigative ophthalmology & visual science.

[53]  L. Aiello,et al.  Hypoxic regulation of vascular endothelial growth factor in retinal cells. , 1995, Archives of ophthalmology.

[54]  J. Stone,et al.  Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity , 1995, Nature Medicine.

[55]  H. Kaplan,et al.  Distribution of growth factors in subfoveal neovascular membranes in age-related macular degeneration and presumed ocular histoplasmosis syndrome. , 1995, American journal of ophthalmology.

[56]  G. Naumann The Bowman Lecture , 1995, Eye.

[57]  P. D'Amore,et al.  Mechanisms of retinal and choroidal neovascularization. , 1994, Investigative ophthalmology & visual science.

[58]  M. Uyama,et al.  [Experimental choroidal neovascularization in the rat]. , 1994, Nippon Ganka Gakkai zasshi.

[59]  R. Frank,et al.  Growth factor localization in choroidal neovascular membranes of age-related macular degeneration. , 1994, Investigative ophthalmology & visual science.

[60]  P T de Jong,et al.  Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging. , 1994, Investigative ophthalmology & visual science.

[61]  A. Bird,et al.  Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane. , 1994, Archives of ophthalmology.

[62]  W R Green,et al.  Age-related Macular Degeneration Histopathologic Studies: The 1992 Lorenz E. Zimmerman Lecture , 1993, Ophthalmology.

[63]  P Sternberg,et al.  Immunohistochemical and histochemical properties of surgically excised subretinal neovascular membranes in age-related macular degeneration. , 1992, American journal of ophthalmology.

[64]  M. Uyama [Choroidal neovascularization, experimental and clinical study]. , 1991, Nippon Ganka Gakkai zasshi.

[65]  D. Ruiter,et al.  Differential expression of markers for endothelial cells, pericytes, and basal lamina in the microvasculature of tumors and granulation tissue. , 1991, The American journal of pathology.

[66]  Jie Li,et al.  Angiogenesis in wound repair: Angiogenic growth factors and the extracellular matrix , 2003, Microscopy research and technique.

[67]  A. Luttun,et al.  Placental growth factor (PlGF) and its receptor Flt-1 (VEGFR-1): novel therapeutic targets for angiogenic disorders. , 2002, Annals of the New York Academy of Sciences.

[68]  J. Ji Pigment epithelium derived factor:a potent inhibitor of angiogenesis , 2002 .

[69]  内田 博子,et al.  Production and accumulation of thrombospondin-1 in human retinal pigment epithelial cells , 2001 .

[70]  B. Lafaut Clinicopathologic correlation of surgically removed submacular tissue. , 2000, Bulletin de la Societe belge d'ophtalmologie.

[71]  D. Yew,et al.  Time-course expression of vascular endothelial growth factor as related to the development of the retinochoroidal vasculature in rats , 1998, Experimental Brain Research.

[72]  R. Frank Growth factors in age-related macular degeneration: pathogenic and therapeutic implications. , 1997, Ophthalmic research.

[73]  J. Folkman,et al.  Angiogenesis and angiogenesis inhibition: an overview. , 1997, EXS.

[74]  C. Barnstable,et al.  Differentiation and transdifferentiation of the retinal pigment epithelium. , 1997, International review of cytology.

[75]  J. Folkman,et al.  Hypoxic Induction of Endothelial Cell Growth Factors in Retinal Cells: Identification and Characterization of Vascular Endothelial Growth Factor (VEGF) as the Mitogen , 1995 .

[76]  W. Green CLINICOPATHOLOGIC STUDIES OF TREATED CHOROIDAL NEOVASCULAR MEMBRANES: A Review and Report of Two Cases , 1991, Retina.