Neurocognitive development of relational reasoning.

Relational reasoning is an essential component of fluid intelligence, and is known to have a protracted developmental trajectory. To date, little is known about the neural changes that underlie improvements in reasoning ability over development. In this event-related functional magnetic resonance imaging (fMRI) study, children aged 8-12 and adults aged 18-25 performed a relational reasoning task adapted from Raven's Progressive Matrices. The task included three levels of relational reasoning demands: REL-0, REL-1, and REL-2. Children exhibited disproportionately lower accuracy than adults on trials that required integration of two relations (REL-2). Like adults, children engaged lateral prefrontal cortex (PFC) and parietal cortex during task performance; however, they exhibited different time courses and activation profiles, providing insight into their approach to the problems. As in prior studies, adults exhibited increased rostrolateral PFC (RLPFC) activation when relational integration was required (REL-2 > REL-1, REL-0). Children also engaged RLPFC most strongly for REL-2 problems at early stages of processing, but this differential activation relative to REL-1 trials was not sustained throughout the trial. These results suggest that the children recruited RLPFC while processing relations, but failed to use it to integrate across two relations. Relational integration is critical for solving a variety of problems, and for appreciating analogies; the current findings suggest that developmental improvements in this function rely on changes in the profile of engagement of RLPFC, as well as dorsolateral PFC and parietal cortex.

[1]  Charles G. Gross,et al.  REVIEW ■ : Multiple Representations of Space in the Brain , 1995 .

[2]  James K. Kroger,et al.  Recruitment of anterior dorsolateral prefrontal cortex in human reasoning: a parametric study of relational complexity. , 2002, Cerebral cortex.

[3]  Kun Ho Lee,et al.  Neural correlates of superior intelligence: Stronger recruitment of posterior parietal cortex , 2006, NeuroImage.

[4]  Brian Levine,et al.  Cortical thickness of the frontopolar area in typically developing children and adolescents , 2005, NeuroImage.

[5]  Daniel C. Krawczyk,et al.  A Neurocomputational Model of Analogical Reasoning and its Breakdown in Frontotemporal Lobar Degeneration , 2004, Journal of Cognitive Neuroscience.

[6]  Carter Wendelken,et al.  Neurocognitive development of the ability to manipulate information in working memory. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[7]  J. Fuster.  Cortex and mind : unifying cognition , 2003 .

[8]  A M Dale,et al.  Optimal experimental design for event‐related fMRI , 1999, Human brain mapping.

[9]  David Badre,et al.  Analogical reasoning and prefrontal cortex: evidence for separable retrieval and integration mechanisms. , 2004, Cerebral cortex.

[10]  J. Giedd.  Structural Magnetic Resonance Imaging of the Adolescent Brain , 2004, Annals of the New York Academy of Sciences.

[11]  R. Cattell,et al.  Abilities : Their Structure , Growth , and Action , 2015 .

[12]  Abraham Z. Snyder,et al.  The Feasibility of a Common Stereotactic Space for Children and Adults in fMRI Studies of Development , 2002, NeuroImage.

[13]  J. Raven.  STANDARDIZATION OF PROGRESSIVE MATRICES, 1938 , 1941 .

[14]  R. Cattell.  Intelligence : its structure, growth and action , 1987 .

[15]  R. Sternberg,et al.  The development of analogical reasoning processes. , 1979, Journal of experimental child psychology.

[16]  John D E Gabrieli,et al.  Evaluating self-generated information: anterior prefrontal contributions to human cognition. , 2003, Behavioral neuroscience.

[17]  John L. Horn,et al.  Human cognitive capabilities: Gf-Gc theory. , 1997 .

[18]  G L Shulman,et al.  INAUGURAL ARTICLE by a Recently Elected Academy Member:A default mode of brain function , 2001 .

[19]  J. Reichenbach,et al.  The special involvement of the rostrolateral prefrontal cortex in planning abilities: An event-related fMRI study with the Tower of London paradigm , 2006, Neuropsychologia.

[20]  Iroise Dumontheil,et al.  Function and localization within rostral prefrontal cortex (area 10) , 2007, Philosophical Transactions of the Royal Society B: Biological Sciences.

[21]  A. Owen,et al.  Anterior prefrontal cortex: insights into function from anatomy and neuroimaging , 2004, Nature Reviews Neuroscience.

[22]  Suzanne E. Welcome,et al.  Longitudinal Mapping of Cortical Thickness and Brain Growth in Normal Children , 2022 .

[23]  E. Darcy Burgund,et al.  Comparison of functional activation foci in children and adults using a common stereotactic space , 2003, NeuroImage.

[24]  J. Duncan.  Intelligence tests predict brain response to demanding task events , 2003, Nature Neuroscience.

[25]  Thomas F. Nugent,et al.  Dynamic mapping of human cortical development during childhood through early adulthood. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[26]  Cameron S. Carter,et al.  Brain Is to Thought as Stomach Is to ??: Investigating the Role of Rostrolateral Prefrontal Cortex in Relational Reasoning , 2008, Journal of Cognitive Neuroscience.

[27]  S. Bunge,et al.  Neurodevelopmental changes in working memory and cognitive control , 2007, Current Opinion in Neurobiology.

[28]  C. Chabris,et al.  Neural mechanisms of general fluid intelligence , 2003, Nature Neuroscience.

[29]  Jean-Luc Anton,et al.  Region of interest analysis using an SPM toolbox , 2010 .

[30]  T. Achenbach.  Manual for the child behavior checklist/4-18 and 1991 profile , 1991 .

[31]  M. Torrens.  Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268 , 1990 .

[32]  M A Just,et al.  From the SelectedWorks of Marcel Adam Just 1990 What one intelligence test measures : A theoretical account of the processing in the Raven Progressive Matrices Test , 2016 .

[33]  E. Koechlin,et al.  The role of the anterior prefrontal cortex in human cognition , 1999, Nature.

[34]  C. Edelbrock,et al.  Manual for the Child: Behavior Checklist and Revised Child Behavior Profile , 1983 .

[35]  Cameron S. Carter,et al.  Maintaining structured information: An investigation into functions of parietal and lateral prefrontal cortices , 2008, Neuropsychologia.

[36]  J. Desmond,et al.  Neural Substrates of Fluid Reasoning: An fMRI Study of Neocortical Activation during Performance of the Raven's Progressive Matrices Test , 1997, Cognitive Psychology.

[37]  S. Phillips,et al.  Processing capacity defined by relational complexity: implications for comparative, developmental, and cognitive psychology. , 1998, The Behavioral and brain sciences.

[38]  Alan C. Evans,et al.  BrainWeb: Online Interface to a 3D MRI Simulated Brain Database , 1997 .

[39]  James K. Kroger,et al.  Rostrolateral Prefrontal Cortex Involvement in Relational Integration during Reasoning , 2001, NeuroImage.

[40]  Jesper Tegnér,et al.  Brain activity related to working memory and distraction in children and adults. , 2006, Cerebral cortex.

[41]  Hans Forssberg,et al.  Increased Brain Activity in Frontal and Parietal Cortex Underlies the Development of Visuospatial Working Memory Capacity during Childhood , 2002, Journal of Cognitive Neuroscience.

[42]  J. Gabrieli,et al.  The frontopolar cortex and human cognition: Evidence for a rostrocaudal hierarchical organization within the human prefrontal cortex , 2000, Psychobiology.

[43]  K. Holyoak,et al.  A System for Relational Reasoning in Human Prefrontal Cortex , 1999 .

[44]  L. Wood,et al.  From the Authors , 2003, European Respiratory Journal.

[45]  Silvia A. Bunge,et al.  A Brain-Based Account of the Development of Rule Use in Childhood , 2006 .

[46]  Emilio Ferrer,et al.  Neural Correlates of Fluid Reasoning in Children and Adults , 2007, Frontiers in human neuroscience.

[47]  D. Pandya,et al.  Projections to the frontal cortex from the posterior parietal region in the rhesus monkey , 1984, The Journal of comparative neurology.

[48]  K. Holyoak,et al.  Children's development of analogical reasoning: insights from scene analogy problems. , 2006, Journal of experimental child psychology.

[49]  T. Braver,et al.  The Role of Frontopolar Cortex in Subgoal Processing during Working Memory , 2002, NeuroImage.

[50]  Performance on Raven's Progressive Matrices. What makes a difference? , 1994 .