In vitro characterization of physico‐chemical properties, cytotoxicity, bioactivity of urea‐crosslinked hyaluronic acid and sodium ascorbyl phosphate nasal powder formulation

[1]  P. Young,et al.  Co-Spray-Dried Urea Cross-Linked Hyaluronic Acid and Sodium Ascorbyl Phosphate as Novel Inhalable Dry Powder Formulation. , 2019, Journal of pharmaceutical sciences.

[2]  F. Marchetti,et al.  Formulation and Characterization of Native and Crosslinked Hyaluronic Acid Microspheres for Dermal Delivery of Sodium Ascorbyl Phosphate: A Comparative Study , 2018, Pharmaceutics.

[3]  Haili Hu,et al.  Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[4]  Dong Chang Lee,et al.  The effect of urban particulate matter on cultured human nasal fibroblasts , 2018, International forum of allergy & rhinology.

[5]  P. Young,et al.  Combination of urea‐crosslinked hyaluronic acid and sodium ascorbyl phosphate for the treatment of inflammatory lung diseases: An in vitro study , 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[6]  S. Manfredini,et al.  Hyaluronic Acid in the Third Millennium , 2018, Polymers.

[7]  R. Campbell.  Risks and management of long-term corticosteroid use in chronic rhinosinusitis , 2017, Current opinion in otolaryngology & head and neck surgery.

[8]  P. Russo,et al.  Opportunity and challenges of nasal powders: Drug formulation and delivery , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[9]  G. Valacchi,et al.  Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study , 2017, Molecules.

[10]  M. Gelardi,et al.  Pathological and cytological changes of the nasal mucosa in acute rhinosinusitis: the role of hyaluronic acid as supportive therapy. , 2017, European review for medical and pharmacological sciences.

[11]  A. Licari,et al.  The role of upper airway pathology as a co-morbidity in severe asthma , 2017, Expert review of respiratory medicine.

[12]  E. Dursun,et al.  The Effects of Curcumin on Wound Healing in a Rat Model of Nasal Mucosal Trauma , 2017, Evidence-based complementary and alternative medicine : eCAM.

[13]  F. Sonvico,et al.  Development of a Soluplus budesonide freeze-dried powder for nasal drug delivery , 2017, Drug development and industrial pharmacy.

[14]  A. Licari,et al.  The Nose and the Lung: United Airway Disease? , 2017, Front. Pediatr..

[15]  Ruchin G. Patel.  Nasal Anatomy and Function , 2017, Facial Plastic Surgery.

[16]  S. Manfredini,et al.  Hyaluronic Acid Fillers in Soft Tissue Regeneration , 2017, Facial Plastic Surgery.

[17]  Jane E. Cavanaugh,et al.  Improved Flux of Levodopa via Direct Deposition of Solid Microparticles on Nasal Tissue , 2016, AAPS PharmSciTech.

[18]  G. Guerra,et al.  Nasal mucosa healing after endoscopic sinus surgery in chronic rhinosinusitis of elderly patients: role of topic alpha-tocopherol acetate , 2017, Aging Clinical and Experimental Research.

[19]  A. Greco,et al.  Olfactory dysfunction in acute rhinosinusitis: intranasal sodium hyaluronate as adjuvant treatment , 2017, European Archives of Oto-Rhino-Laryngology.

[20]  Daniela Traini,et al.  Application of RPMI 2650 nasal cell model to a 3D printed apparatus for the testing of drug deposition and permeation of nasal products. , 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[21]  C. Deng,et al.  Airborne Fine Particulate Matter Induces Oxidative Stress and Inflammation in Human Nasal Epithelial Cells. , 2016, The Tohoku journal of experimental medicine.

[22]  G. Oliveto,et al.  Hyaluronic acid and upper airway inflammation in pediatric population: A systematic review. , 2016, International journal of pediatric otorhinolaryngology.

[23]  L. Drago,et al.  Biomarkers in Lung Diseases : from Pathogenesis to Prediction to New Therapies The role of hyaluronan in the pathobiology and treatment of respiratory disease , 2016 .

[24]  R. Ambrus,et al.  Cytotoxicity of Different Excipients on RPMI 2650 Human Nasal Epithelial Cells , 2016, Molecules.

[25]  R. Gagliardo,et al.  Effect of High, Medium, and Low Molecular Weight Hyaluronan on Inflammation and Oxidative Stress in an In Vitro Model of Human Nasal Epithelial Cells , 2016, Mediators of inflammation.

[26]  C. Cingi,et al.  Is resveratrol therapeutic when used to treat allergic rhinitisinitis in rats? , 2016, Clinical and investigative medicine. Medecine clinique et experimentale.

[27]  K. Chauhan,et al.  Role of antioxidants on the clinical outcome of patients with perennial allergic rhinitis , 2016, Allergy & rhinology.

[28]  F. Sonvico,et al.  Dry powder nasal drug delivery: challenges, opportunities and a study of the commercial Teijin Puvlizer Rhinocort device and formulation , 2016, Drug development and industrial pharmacy.

[29]  M. Cassano,et al.  Cytofunctional Changes in Nasal Ciliated Cells in Patients Treated with Hyaluronate after Nasal Surgery , 2016, American journal of rhinology & allergy.

[30]  N. Quaranta,et al.  Ancillary therapy of intranasal T-LysYal® for patients with allergic, non-allergic, and mixed rhinitis. , 2016, Journal of biological regulators and homeostatic agents.

[31]  A. Scarpa,et al.  Hyaluronan in the Treatment of Chronic Rhinosinusitis with Nasal Polyposis , 2015, Indian Journal of Otolaryngology and Head & Neck Surgery.

[32]  M. Kreft,et al.  The Characterization of the Human Nasal Epithelial Cell Line RPMI 2650 Under Different Culture Conditions and Their Optimization for an Appropriate in vitro Nasal Model , 2014, Pharmaceutical Research.

[33]  R. Osman,et al.  Nasal polysaccharides-glucose regulator microparticles: optimization, tolerability and antidiabetic activity in rats. , 2014, Carbohydrate polymers.

[34]  乌戈·拉法埃洛·希特内斯,et al.  Cross-linked hyaluronic acid, process for the preparation thereof and use thereof in the aesthetic field , 2014 .

[35]  R. Mladina,et al.  The Potential Role of Hyaluronan in Minimizing Symptoms and Preventing Exacerbations of Chronic Rhinosinusitis , 2014, American journal of rhinology & allergy.

[36]  G. Ciprandi,et al.  Inhaled hyaluronic acid as ancillary treatment in children with bacterial acute rhinopharyngitis. , 2014, Journal of biological regulators and homeostatic agents.

[37]  P. Lackie,et al.  Culture of Primary Ciliary Dyskinesia Epithelial Cells at Air-Liquid Interface Can Alter Ciliary Phenotype but Remains a Robust and Informative Diagnostic Aid , 2014, PloS one.

[38]  I. Jaspers,et al.  Culturing of human nasal epithelial cells at the air liquid interface. , 2013, Journal of visualized experiments : JoVE.

[39]  N. Quaranta,et al.  Intranasal sodium hyaluronate on the nasal cytology of patients with allergic and nonallergic rhinitis , 2013, International forum of allergy & rhinology.

[40]  N. Quaranta,et al.  Effect of sodium hyaluronate on mucociliary clearance after functional endoscopic sinus surgery. , 2013, European annals of allergy and clinical immunology.

[41]  S. Reichl,et al.  Cultivation of RPMI 2650 cells as an in‐vitro model for human transmucosal nasal drug absorption studies: optimization of selected culture conditions , 2012, The Journal of pharmacy and pharmacology.

[42]  W. Doub,et al.  Measurement of Drug in Small Particles from Aqueous Nasal Sprays by Andersen Cascade Impactor , 2012, Pharmaceutical Research.

[43]  H. Goossens,et al.  EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. , 2012, Rhinology.

[44]  X. Shu,et al.  The Evaluation of Two New Hyaluronan Hydrogels as Nasal Dressing in the Rabbit Maxillary Sinus , 2012, American journal of rhinology & allergy.

[45]  Glenis K Scadding,et al.  Allergic rhinitis , 2018, Allergy, Asthma & Clinical Immunology.

[46]  D. Jarvis,et al.  Asthma in adults and its association with chronic rhinosinusitis: The GA2LEN survey in Europe , 2012, Allergy.

[47]  Harold Kim,et al.  Allergic rhinitis , 2011, Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology.

[48]  D. Caimmi,et al.  Nasal Disease and Asthma , 2011, International journal of immunopathology and pharmacology.

[49]  M. Sağıt,et al.  Effect of antioxidants on the clinical outcome of patients with nasal polyposis. , 2011, The Journal of laryngology and otology.

[50]  M. Bebawy,et al.  Epithelial Profiling of Antibiotic Controlled Release Respiratory Formulations , 2011, Pharmaceutical Research.

[51]  Stephan Reichl,et al.  RPMI 2650 epithelial model and three-dimensional reconstructed human nasal mucosa as in vitro models for nasal permeation studies. , 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[52]  P. Baumeister,et al.  Reduction of oxidative DNA fragmentation by ascorbic acid, zinc and N-acetylcysteine in nasal mucosa tissue cultures. , 2009, Anticancer research.

[53]  A. Falcão,et al.  Intranasal drug delivery: how, why and what for? , 2009, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

[54]  E. Cevher,et al.  Nasal Delivery of High Molecular Weight Drugs , 2009, Molecules.

[55]  David Elad,et al.  Air-conditioning in the human nasal cavity , 2008, Respiratory Physiology & Neurobiology.

[56]  F. Ahsan,et al.  Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies. , 2008, Journal of pharmaceutical sciences.

[57]  H. Schellhorn,et al.  New developments and novel therapeutic perspectives for vitamin C. , 2007, The Journal of nutrition.

[58]  J. Mullol,et al.  Allergic rhinitis: continuous or on demand antihistamine therapy? , 2007, Journal of investigational allergology & clinical immunology.

[59]  Alan L. Miller,et al.  Natural treatment of chronic rhinosinusitis. , 2006, Alternative medicine review : a journal of clinical therapeutic.

[60]  L. Allegra,et al.  Aerosolised hyaluronic acid prevents exercise-induced bronchoconstriction, suggesting novel hypotheses on the correction of matrix defects in asthma. , 2006, Pulmonary pharmacology & therapeutics.

[61]  R. Forteza,et al.  Identification of glycosaminoglycans in human airway secretions. , 2006, American journal of respiratory cell and molecular biology.

[62]  R. Kinget,et al.  Nasal mucoadhesive drug delivery: background, applications, trends and future perspectives. , 2005, Advanced drug delivery reviews.

[63]  J. Kristl,et al.  Investigation of liposomes as carriers of sodium ascorbyl phosphate for cutaneous photoprotection. , 2005, International journal of pharmaceutics.

[64]  Min-Ki Lee,et al.  Air-Liquid Interface Culture of Serially Passaged Human Nasal Epithelial Cell Monolayer for In Vitro Drug Transport Studies , 2005, Drug delivery.

[65]  Min-Ki Lee,et al.  Serially Passaged Human Nasal Epithelial Cell Monolayer for in Vitro Drug Transport Studies , 2003, Pharmaceutical Research.

[66]  L. Johansson,et al.  Prevalence of Nasal Polyps in Adults: The Skovde Population-Based Study , 2003, The Annals of otology, rhinology, and laryngology.

[67]  N. Jones,et al.  The nose and paranasal sinuses physiology and anatomy. , 2001, Advanced drug delivery reviews.

[68]  R A Guilmette,et al.  Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway. , 2001, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

[69]  F. Kelly,et al.  Ozone and the lung: a sensitive issue. , 2000, Molecular aspects of medicine.

[70]  C. Cross,et al.  Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids. , 1999, American journal of physiology. Lung cellular and molecular physiology.

[71]  C. Cross,et al.  Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids. , 1999, The American journal of physiology.

[72]  J. Bastacky,et al.  Ultrastructure of tracheal surface liquid: low-temperature scanning electron microscopy. , 2006, Scanning.

[73]  T. Speed,et al.  Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung. , 1995, Journal of applied physiology.

[74]  R. Gertner,et al.  Treatment of perennial allergic rhinitis with ascorbic acid solution. , 1991, Ear, nose, & throat journal.

[75]  C. Basbaum,et al.  Airway Secretion: A Cell-Specific Analysis , 1988, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.