Effectiveness of partner social support predicts enduring psychological distress after hematopoietic stem cell transplantation.

OBJECTIVE Hematopoietic stem cell transplant (HSCT) survivors who are 1 to 3 years posttransplant are challenged by the need to resume valued social roles and activities--a task that may be complicated by enduring transplant-related psychological distress common in this patient population. The present study investigated whether transplant survivors who receive adequate social support from their spouse or intimate partner experience lower distress. METHOD Effects of receiving a greater quantity of partner support (a common approach to studying enacted support) were compared with effects of receiving more effective partner support (i.e., support that more closely matches their needs in terms of its quantity and quality). Men and women (N = 230) who were 1 to 3 years posttransplant completed measures of partner support quantity (Manne & Schnoll, 2001), partner social support effectiveness (Rini & Dunkel Schetter, 2010), and psychological distress (Brief Symptom Inventory; Derogatis & Spencer, 1982). Potential medical and sociodemographic confounds were controlled in analyses. RESULTS As hypothesized, survivors reported less distress when they received more effective partner support (p < .001). Quantity of partner support was not associated with distress (p = .23). An interaction revealed that when partner support was effective, the quantity of support survivors received was not associated with their distress (p = .90); however, when partner support was ineffective, receiving a greater quantity of partner support was associated with substantially elevated distress (p = .002). CONCLUSIONS Findings suggest that clinical approaches to addressing or preventing enduring distress after HSCT should target features of partner support related to its appraised effectiveness.

[1]  M. Aljurf,et al.  Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation. , 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[2]  C. Rini,et al.  Randomized clinical trial of telephone-administered cognitive-behavioral therapy to reduce post-traumatic stress disorder and distress symptoms after hematopoietic stem-cell transplantation. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[3]  P. Hari,et al.  Access to hematopoietic stem cell transplantation , 2010, Cancer.

[4]  J. Davila,et al.  Support processes in intimate relationships , 2010 .

[5]  F. Awan,et al.  How we approach patient evaluation for hematopoietic stem cell transplantation , 2010, Bone Marrow Transplantation.

[6]  Hong-Jin Kim,et al.  Partner‐assisted emotional disclosure for patients with gastrointestinal cancer , 2009, Cancer.

[7]  P. Jacobsen,et al.  Do Coping and Social Support Predict Depression and Anxiety in Patients Undergoing Hematopoietic Stem Cell Transplantation? , 2009, Journal of psychosocial oncology.

[8]  P. Monahan,et al.  Adaptation of family caregivers during the acute phase of adult BMT , 2009, Bone Marrow Transplantation.

[9]  W. Redd,et al.  Physical, psychological, and social sequelae following hematopoietic stem cell transplantation: a review of the literature , 2009, Psycho-oncology.

[10]  S. Sexson,et al.  Social support from family and friends as a buffer of low spousal support among mothers of critically ill children: A multilevel modeling approach. , 2008, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[11]  S. Manne,et al.  Long-Term Trajectories of Psychological Adaptation Among Women Diagnosed With Gynecological Cancers , 2008, Psychosomatic medicine.

[12]  G. Winkel,et al.  Psychological distress in long‐term survivors of hematopoietic stem cell transplantation , 2008, Psycho-oncology.

[13]  M. Bevans,et al.  The symptom experience in the first 100 days following allogeneic hematopoietic stem cell transplantation (HSCT) , 2008, Supportive Care in Cancer.

[14]  B. Kurland,et al.  Sexual function changes during the 5 years after high-dose treatment and hematopoietic cell transplantation for malignancy, with case-matched controls at 5 years. , 2008, Blood.

[15]  E. Altmaier,et al.  Social Support and Depression among Bone Marrow Transplant Patients , 2008, Journal of health psychology.

[16]  S. Manne,et al.  Coping and communication-enhancing intervention versus supportive counseling for women diagnosed with gynecological cancers. , 2007, Journal of consulting and clinical psychology.

[17]  J. Beaumont,et al.  Late effects of cancer and hematopoietic stem-cell transplantation on spouses or partners compared with survivors and survivor-matched controls. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[18]  E. Altmaier,et al.  Social Support, Optimism, and Self-Efficacy Predict Physical and Emotional Well-Being After Bone Marrow Transplantation , 2007, Journal of psychosocial oncology.

[19]  L. Nail,et al.  Explaining Family Caregiver Role Strain Following Autologous Blood and Marrow Transplantation , 2006, Journal of psychosocial oncology.

[20]  M. Hasenbring,et al.  Social support and quality of life of patients prior to stem cell or bone marrow transplantation. , 2006, British journal of health psychology.

[21]  Mo Ray.  Informal care in the context of long-term marriage: The challenge to practice , 2006 .

[22]  Curt A. Sandman,et al.  Effective social support: Antecedents and consequences of partner support during pregnancy , 2006 .

[23]  Edward A Copelan,et al.  Hematopoietic stem-cell transplantation. , 2006, The New England journal of medicine.

[24]  Louis J. Wagner,et al.  Coping among older‐adult, long‐term cancer survivors , 2006, Psycho-oncology.

[25]  H. Hurwitz,et al.  Disclosure between patients with gastrointestinal cancer and their spouses , 2005, Psycho-oncology.

[26]  I. Bumeder,et al.  Social Support, Affectivity, and the Quality of Life of Patients and Their Support-Givers Prior to Stem Cell Transplantation , 2005, Journal of psychosocial oncology.

[27]  I. Bumeder,et al.  Is perceived social support a predictor of survival for patients undergoing autologous peripheral blood stem cell transplantation? , 2005, Psycho-oncology.

[28]  A. Bosi,et al.  Allogeneic stem cell transplantation. , 2005, Transplantation proceedings.

[29]  J. Beaumont,et al.  Long-term health-related quality of life, growth, and spiritual well-being after hematopoietic stem-cell transplantation. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[30]  Thomas J. Smith,et al.  Assessment of Optimal Size and Composition of the U.S. National Registry of Hematopoietic Stem Cell Donors , 2004, Transplantation.

[31]  B. Storer,et al.  Recovery and long-term function after hematopoietic cell transplantation for leukemia or lymphoma. , 2004, JAMA.

[32]  David C. Atkins,et al.  Traditional versus integrative behavioral couple therapy for significantly and chronically distressed married couples. , 2004, Journal of consulting and clinical psychology.

[33]  H. Lazarus,et al.  Allogeneic Stem Cell Transplantation , 2002, Current Clinical Oncology.

[34]  P. Jacobsen,et al.  Predictors of posttraumatic stress disorder symptomatology following bone marrow transplantation for cancer. , 2002, Journal of consulting and clinical psychology.

[35]  S. Manne,et al.  Measuring Supportive and Unsupportive Responses During Cancer Treatment: A Factor Analytic Assessment of the Partner Responses to Cancer Inventory , 2001, Journal of Behavioral Medicine.

[36]  B. Given,et al.  Family Support in Advanced Cancer , 2001, CA: a cancer journal for clinicians.

[37]  K. Cornetta,et al.  Psychosocial adjustment of patients and caregivers prior to allogeneic bone marrow transplantation , 2001, Bone Marrow Transplantation.

[38]  M. R. Widows,et al.  Relation of Psychological Vulnerability Factors to Posttraumatic Stress Disorder Symptomatology in Bone Marrow Transplant Recipients , 2000, Psychosomatic medicine.

[39]  N. Jacobson,et al.  Integrative behavioral couple therapy: an acceptance-based, promising new treatment for couple discord. , 2000, Journal of consulting and clinical psychology.

[40]  G. Phillips,et al.  Patients’ psychosocial concerns following stem cell transplantation , 1999, Bone Marrow Transplantation.

[41]  S. McCann,et al.  Psychosocial adaptation of patients and families following bone marrow transplantation: a prospective, longitudinal study , 1998, Bone Marrow Transplantation.

[42]  B. Craven,et al.  Quality of life and psychological distress of bone marrow transplant recipients: the ‘time trajectory’ to recovery over the first year , 1998, Bone Marrow Transplantation.

[43]  A. Molassiotis,et al.  Perceived social support, family environment and psychosocial recovery in bone marrow transplant long-term survivors. , 1997, Social science & medicine.

[44]  K. Compton,et al.  Needs and experiences of family caregivers during marrow transplantation. , 1996, Oncology nursing forum.

[45]  L. Fallowfield.  Psychosocial interventions in cancer , 1995, BMJ.

[46]  C. Barker,et al.  The partner relationship in psychological response to breast cancer. , 1995, Social science & medicine.

[47]  K. Sullivan,et al.  Recovery after allogeneic marrow transplantation: prospective study of predictors of long-term physical and psychosocial functioning. , 1993, Bone marrow transplantation.

[48]  B. Curbow,et al.  The Family: The Other Side of Bone Marrow Transplantation , 1992 .

[49]  F. Fincham,et al.  Attributions and behavior in marital interaction. , 1992, Journal of personality and social psychology.

[50]  P. Franks,et al.  Association of social relationships with depressive symptoms: Testing an alternative to social support. , 1992 .

[51]  S. Piantadosi,et al.  Health, functional status, and employment of adult survivors of bone marrow transplantation. , 1991, Annals of internal medicine.

[52]  M. Pagel,et al.  Social networks: we get by with (and in spite of) a little help from our friends. , 1987, Journal of personality and social psychology.

[53]  K. Rook,et al.  The negative side of social interaction: impact on psychological well-being. , 1984, Journal of personality and social psychology.

[54]  R. Storb,et al.  Allogeneic Bone‐Marrow Transplantation , 1983, Immunological reviews.

[55]  D. Karnofsky,et al.  The use of the nitrogen mustards in the palliative treatment of carcinoma. With particular reference to bronchogenic carcinoma , 1948 .

[56]  Heather Laurie.  Social support from family and friends , 2012 .

[57]  F. Harper,et al.  Psychological Care of Adult Allogeneic Transplant Patients , 2010 .

[58]  Michelle Bishop.  Psychosocial sequelae of hematopoietic cell transplantation in survivors and caregivers. , 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[59]  Stephanie J. Lee.  Quality of Life Issues Post-Transplantation , 2008 .

[60]  H. Deeg,et al.  Stem cell transplantation: supportive care and long-term complications. , 2002, Hematology. American Society of Hematology. Education Program.

[61]  B. Karney,et al.  PERSONALITY AND SOCIAL PSYCHOLOGY BULLETIN McNulty, Karney / ATTRIBUTIONS IN MARRIAGE Attributions in Marriage: Integrating Specific and Global Evaluations of a Relationship , 2001 .

[62]  D. Spiegel,et al.  Psychosocial interventions in cancer: Group therapy techniques. , 2001 .

[63]  A. Baum,et al.  Psychosocial interventions for cancer. , 2001 .

[64]  S. Cessie,et al.  Psychological functioning and quality of life following bone marrow transplantation: a 3-year follow-up study. , 2000, Journal of psychosomatic research.

[65]  J. Rodrigue,et al.  Morbidity and mortality following bone marrow transplantation: Predictive utility of pre-BMT affective functioning, compliance, and social support stability , 1999, International journal of behavioral medicine.

[66]  P. Shaver,et al.  An attachment-theoretical approach to caregiving in romantic relationships. , 1994 .

[67]  C. Dunkel-Schetter,et al.  Patterns of coping with cancer. , 1992, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.