Transforming Growth Factor type beta and Smad family signaling in stem cell function.
暂无分享,去创建一个
[1] Michel Sadelain,et al. Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation , 2009, Proceedings of the National Academy of Sciences.
[2] Hitoshi Niwa,et al. A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells , 2009, Nature.
[3] C. Lim,et al. Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells , 2009, PLoS biology.
[4] M. Baron,et al. Embryonic fates for extraembryonic lineages: New perspectives , 2009, Journal of cellular biochemistry.
[5] Roger A. Pedersen,et al. Early Cell Fate Decisions of Human Embryonic Stem Cells and Mouse Epiblast Stem Cells Are Controlled by the Same Signalling Pathways , 2009, PloS one.
[6] David J. Mooney,et al. Growth Factors, Matrices, and Forces Combine and Control Stem Cells , 2009, Science.
[7] L. David,et al. Emerging role of bone morphogenetic proteins in angiogenesis. , 2009, Cytokine & growth factor reviews.
[8] K. Mesbah,et al. Signaling Pathways Controlling Second Heart Field Development , 2009, Circulation research.
[9] Huck-Hui Ng,et al. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. , 2009, Cell stem cell.
[10] C. Heldin,et al. Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition. , 2009, Current opinion in cell biology.
[11] C. Hill,et al. Tgf-beta superfamily signaling in embryonic development and homeostasis. , 2009, Developmental cell.
[12] M. Romano. Targeting TGFbeta-mediated processes in cancer. , 2009, Current opinion in drug discovery & development.
[13] M. Tomishima,et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling , 2009, Nature Biotechnology.
[14] Roberto Mayor,et al. Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction , 2009, Development.
[15] L. Attisano,et al. A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling , 2009, The Journal of cell biology.
[16] Alexander Meissner,et al. Induced pluripotent stem cells: current progress and potential for regenerative medicine. , 2009, Trends in molecular medicine.
[17] Samy Lamouille,et al. TGF-β-induced epithelial to mesenchymal transition , 2009, Cell Research.
[18] D. Hess,et al. Amnion: A Potent Graft Source for Cell Therapy in Stroke , 2009, Cell transplantation.
[19] Konstantinos J. Mavrakis,et al. Graded Smad2/3 Activation Is Converted Directly into Levels of Target Gene Expression in Embryonic Stem Cells , 2009, PloS one.
[20] L. Gunhaga,et al. Wnt-regulated temporal control of BMP exposure directs the choice between neural plate border and epidermal fate , 2009, Development.
[21] D. Melton,et al. Nuclear Reprogramming in Cells , 2008, Science.
[22] M. Grompe,et al. Generation and Regeneration of Cells of the Liver and Pancreas , 2008, Science.
[23] Y. Inoue,et al. Regulation of TGF‐β family signaling by E3 ubiquitin ligases , 2008, Cancer science.
[24] Hsu-hsin Chen,et al. The Growth Factor Environment Defines Distinct Pluripotent Ground States in Novel Blastocyst-Derived Stem Cells , 2008, Cell.
[25] K. Miyazono,et al. Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway , 2008, Oncogene.
[26] F. Tang,et al. Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. , 2008, Cell stem cell.
[27] Shigeo Saito,et al. Establishment and characterization of a pluripotent stem cell line derived from human amniotic membranes and initiation of germ layers in vitro , 2008, Human Cell.
[28] J. Bertram,et al. Bone morphogenetic protein signaling in the developing kidney: present and future. , 2008, Differentiation; research in biological diversity.
[29] Xuedong Liu,et al. Decoding the quantitative nature of TGF-beta/Smad signaling. , 2008, Trends in cell biology.
[30] M. Pisano,et al. BMP signaling dynamics in embryonic orofacial tissue , 2008, Journal of cellular physiology.
[31] Xin-Hua Feng,et al. To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications. , 2008, Cellular signalling.
[32] P. Dijke,et al. Role of TGF- β in the Tumor Stroma , 2008 .
[33] C. Please,et al. Stochasticity and the Molecular Mechanisms of Induced Pluripotency , 2008, PloS one.
[34] R. Flavell,et al. TGF-β: A Master of All T Cell Trades , 2008, Cell.
[35] G. Pan,et al. NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. , 2008, Cell stem cell.
[36] R. Peterson,et al. Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells , 2008, PloS one.
[37] M. Buckingham,et al. Skeletal muscle stem cells. , 2008, Current opinion in genetics & development.
[38] A. Kaye,et al. Transforming growth factor-beta (TGF-β) and brain tumours , 2008, Journal of Clinical Neuroscience.
[39] I. Black,et al. Fate of amnion-derived stem cells transplanted to the fetal rat brain: migration, survival and differentiation , 2008, Journal of cellular and molecular medicine.
[40] J. Thomson,et al. Pluripotent stem cell lines. , 2008, Genes & development.
[41] Li-Fang Chu,et al. Ronin Is Essential for Embryogenesis and the Pluripotency of Mouse Embryonic Stem Cells , 2008, Cell.
[42] N. D. Clarke,et al. Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells , 2008, Cell.
[43] Marianne Bronner-Fraser,et al. A gene regulatory network orchestrates neural crest formation , 2008, Nature Reviews Molecular Cell Biology.
[44] V. Kaartinen,et al. Functional redundancy of TGF-beta family type I receptors and receptor-Smads in mediating anti-Mullerian hormone-induced Mullerian duct regression in the mouse. , 2008, Biology of reproduction.
[45] M. Pucéat. Protocols for cardiac differentiation of embryonic stem cells. , 2008, Methods.
[46] Y. Sasai,et al. Ectodermal Factor Restricts Mesoderm Differentiation by Inhibiting p53 , 2008, Cell.
[47] S. Piccolo. p53 Regulation Orchestrates the TGF-β Response , 2008, Cell.
[48] Yukio Nakamura,et al. Induced in vitro differentiation of neural-like cells from human amnion-derived fibroblast-like cells , 2008, Human Cell.
[49] T. Yamashita,et al. BMP inhibition enhances axonal growth and functional recovery after spinal cord injury , 2008, Journal of neurochemistry.
[50] J. Reiter,et al. Neur-ons and neur-offs: regulators of neural induction in vertebrate embryos and embryonic stem cells. , 2008, Human molecular genetics.
[51] S. Wahl,et al. TGF-beta and tumors--an ill-fated alliance. , 2008, Current opinion in immunology.
[52] Michael J Yost,et al. Novel therapies for scar reduction and regenerative healing of skin wounds. , 2008, Trends in biotechnology.
[53] S. Orkin,et al. An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells , 2008, Cell.
[54] Michael O. Dorschner,et al. Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells. , 2008, Genes & development.
[55] J. C. McDermott,et al. Transforming growth factor-β and myostatin signaling in skeletal muscle , 2008 .
[56] Bing Ren,et al. Unraveling epigenetic regulation in embryonic stem cells. , 2008, Cell stem cell.
[57] Göran Karlsson,et al. Signaling pathways governing stem-cell fate. , 2008, Blood.
[58] C. Mummery,et al. Adult Neurogenesis Requires Smad4-Mediated Bone Morphogenic Protein Signaling in Stem Cells , 2008, The Journal of Neuroscience.
[59] Yuri Kotliarov,et al. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. , 2008, Cancer cell.
[60] Richard A Flavell,et al. ‘Yin–Yang’ functions of transforming growth factor‐β and T regulatory cells in immune regulation , 2007, Immunological reviews.
[61] S. Whittemore,et al. Bone Morphogenetic Protein Signaling and Olig1/2 Interact to Regulate the Differentiation and Maturation of Adult Oligodendrocyte Precursor Cells , 2007, Stem cells.
[62] Bernhard Schmierer,et al. TGFβ–SMAD signal transduction: molecular specificity and functional flexibility , 2007, Nature Reviews Molecular Cell Biology.
[63] T. Ichisaka,et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.
[64] E. Robertis,et al. Integrating Patterning Signals: Wnt/GSK3 Regulates the Duration of the BMP/Smad1 Signal , 2007, Cell.
[65] F. Guillemot. Spatial and temporal specification of neural fates by transcription factor codes , 2007, Development.
[66] P. Dijke,et al. Extracellular control of TGFβ signalling in vascular development and disease , 2007, Nature Reviews Molecular Cell Biology.
[67] Martin M. Matzuk,et al. Conditional Deletion of Smad1 and Smad5 in Somatic Cells of Male and Female Gonads Leads to Metastatic Tumor Development in Mice , 2007, Molecular and Cellular Biology.
[68] M. Buckingham,et al. The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions. , 2007, Annual review of cell and developmental biology.
[69] C. Heldin,et al. Signaling networks guiding epithelial–mesenchymal transitions during embryogenesis and cancer progression , 2007, Cancer science.
[70] Lila R Collins,et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts , 2007, Nature Biotechnology.
[71] R. Derynck,et al. Differentiation plasticity regulated by TGF-β family proteins in development and disease , 2007, Nature Cell Biology.
[72] L. Mishra,et al. TGF-β Signaling in Development , 2007, Science's STKE.
[73] M. Trotter,et al. Derivation of pluripotent epiblast stem cells from mammalian embryos , 2007, Nature.
[74] R. McKay,et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells , 2007, Nature.
[75] M. Takenaga,et al. Regulated Nodal signaling promotes differentiation of the definitive endoderm and mesoderm from ES cells , 2007, Journal of Cell Science.
[76] S. Yamanaka. Strategies and new developments in the generation of patient-specific pluripotent stem cells. , 2007, Cell stem cell.
[77] M. Götz,et al. Signaling in adult neurogenesis: from stem cell niche to neuronal networks , 2007, Current Opinion in Neurobiology.
[78] Elizabeth Gould,et al. How widespread is adult neurogenesis in mammals? , 2007, Nature Reviews Neuroscience.
[79] Ali H. Brivanlou,et al. Signaling Pathways in Cancer and Embryonic Stem Cells , 2007, Stem Cell Reviews.
[80] Leonid A. Mirny,et al. Zfx Controls the Self-Renewal of Embryonic and Hematopoietic Stem Cells , 2007, Cell.
[81] E. Kremmer,et al. CHD4/Mi-2beta activity is required for the positioning of the mesoderm/neuroectoderm boundary in Xenopus. , 2007, Genes & development.
[82] P. Dijke,et al. Negative regulation of TGF-β receptor/Smad signal transduction , 2007 .
[83] O. Brüstle,et al. Bone Morphogenetic Protein‐Mediated Modulation of Lineage Diversification During Neural Differentiation of Embryonic Stem Cells , 2007, Stem cells.
[84] Hitoshi Niwa,et al. How is pluripotency determined and maintained? , 2007, Development.
[85] Hiroshi I. Suzuki,et al. Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells , 2006, Journal of Cell Science.
[86] G. Broggi,et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells , 2006, Nature.
[87] M. Buckingham. Myogenic progenitor cells and skeletal myogenesis in vertebrates. , 2006, Current opinion in genetics & development.
[88] F. Hoffmann,et al. Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA. , 2006, Molecular biology of the cell.
[89] E. Bosman,et al. Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels , 2006, Development.
[90] S. Yamanaka,et al. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.
[91] Y. Henis,et al. Different Routes of Bone Morphogenic Protein (BMP) Receptor Endocytosis Influence BMP Signaling , 2006, Molecular and Cellular Biology.
[92] L. Attisano,et al. Ubiquitin-dependent regulation of TGFbeta signaling in cancer. , 2006, Neoplasia.
[93] Fred H. Gage,et al. Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells , 2006, Proceedings of the National Academy of Sciences.
[94] Dinender K. Singla,et al. wnt3a but not wnt11 supports self-renewal of embryonic stem cells. , 2006, Biochemical and biophysical research communications.
[95] S. Karlsson,et al. A Road Map Toward Defining the Role of Smad Signaling in Hematopoietic Stem Cells , 2006, Stem cells.
[96] E. D. Robertis,et al. Spemann's organizer and self-regulation in amphibian embryos , 2006, Nature Reviews Molecular Cell Biology.
[97] X. Chen,et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells , 2006, Nature Genetics.
[98] F. Gage,et al. Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification , 2006, Nature Clinical Practice Cardiovascular Medicine.
[99] Angshumoy Roy,et al. Deconstructing mammalian reproduction: using knockouts to define fertility pathways. , 2006, Reproduction.
[100] D. van der Kooy,et al. Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences , 2006, The Journal of cell biology.
[101] T. Magnuson,et al. Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3. , 2005, Developmental biology.
[102] Tsutomu Chiba,et al. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells , 2005, Nature Biotechnology.
[103] Toshio Miki,et al. Stem Cell Characteristics of Amniotic Epithelial Cells , 2005, Stem cells.
[104] R. Derynck,et al. SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS , 2005 .
[105] P. Zandstra,et al. Culture development for human embryonic stem cell propagation: molecular aspects and challenges. , 2005, Current opinion in biotechnology.
[106] R. Pedersen,et al. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells , 2005, Journal of Cell Science.
[107] Chikara Furusawa,et al. Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture , 2005, Development.
[108] Jonas Larsson,et al. The role of Smad signaling in hematopoiesis , 2005, Oncogene.
[109] P. Courtoy,et al. Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. , 2005, Genes & development.
[110] J. Rubenstein,et al. Pax6 Is Required for Making Specific Subpopulations of Granule and Periglomerular Neurons in the Olfactory Bulb , 2005, The Journal of Neuroscience.
[111] M. Götz,et al. Neuronal fate determinants of adult olfactory bulb neurogenesis , 2005, Nature Neuroscience.
[112] S. Vukicevic,et al. Bone morphogenetic proteins in development and homeostasis of kidney. , 2005, Cytokine & growth factor reviews.
[113] T. Iwama,et al. Culture method for the induction of neurospheres from mouse embryonic stem cells by coculture with PA6 stromal cells , 2005, Journal of neuroscience research.
[114] T. Blundell,et al. Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1. , 2005, Developmental cell.
[115] Ariel J. Levine,et al. TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells , 2005 .
[116] Jeffrey L. Wrana,et al. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling , 2005, Nature Reviews Molecular Cell Biology.
[117] François Guillemot,et al. Mash1 specifies neurons and oligodendrocytes in the postnatal brain , 2004, The EMBO journal.
[118] M. Matzuk,et al. Genetic models for transforming growth factor β superfamily signaling in ovarian follicle development , 2004, Molecular and Cellular Endocrinology.
[119] Holm Zaehres,et al. LIF/STAT3 Signaling Fails to Maintain Self‐Renewal of Human Embryonic Stem Cells , 2004, Stem cells.
[120] A. Bergamaschi,et al. TGFβ/BMP activate the smooth muscle/bone differentiation programs in mesoangioblasts , 2004, Journal of Cell Science.
[121] N. Nakatsuji,et al. STAT3 Is Dispensable for Maintenance of Self‐Renewal in Nonhuman Primate Embryonic Stem Cells , 2004, Stem cells.
[122] C. Mummery,et al. BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. , 2004, Genes & development.
[123] Ana D. Lopez,et al. Maintenance of Pluripotency in Human Embryonic Stem Cells Is STAT3 Independent , 2004, Stem cells.
[124] T. Nikaido,et al. Human amniotic epithelial cells possess hepatocyte-like characteristics and functions. , 2004, Cell structure and function.
[125] A. Roberts,et al. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7. , 2004, Molecular pharmacology.
[126] J. Nichols,et al. BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3 , 2003, Cell.
[127] J. Brennan,et al. Control of early anterior-posterior patterning in the mouse embryo by TGF-beta signalling. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[128] R. Roy,et al. "Amnion Bank"--the use of long term glycerol preserved amniotic membranes in the management of superficial and superficial partial thickness burns. , 2003, Burns : journal of the International Society for Burn Injuries.
[129] Jeffrey L. Wrana,et al. Distinct endocytic pathways regulate TGF-β receptor signalling and turnover , 2003, Nature Cell Biology.
[130] Austin G Smith,et al. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture , 2003, Nature Biotechnology.
[131] Y. Matsui,et al. SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast , 2002, Mechanisms of Development.
[132] B. Olson,et al. Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542. , 2002, Molecular pharmacology.
[133] A. Reith,et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. , 2002, Molecular pharmacology.
[134] Ali H. Brivanlou,et al. Neural induction, the default model and embryonic stem cells , 2002, Nature Reviews Neuroscience.
[135] E. Robertson,et al. Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. , 2001, Development.
[136] B. Hogan,et al. Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. , 2001, Genes & development.
[137] M. Matzuk,et al. Smad5 is required for mouse primordial germ cell development , 2001, Mechanisms of Development.
[138] J. García-Verdugo,et al. Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis , 2000, Neuron.
[139] E. D. De Robertis,et al. Endodermal Nodal-related signals and mesoderm induction in Xenopus. , 2000, Development.
[140] G. Cossu,et al. Wnt signaling and the activation of myogenesis in mammals , 1999, The EMBO journal.
[141] G. Martin,et al. Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. , 1999, Genes & development.
[142] K. Zaret,et al. Initiation of mammalian liver development from endoderm by fibroblast growth factors. , 1999, Science.
[143] T. Bouwmeester,et al. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals , 1999, Nature.
[144] Liliana Attisano,et al. SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor , 1998, Cell.
[145] J. Thomson,et al. Embryonic stem cell lines derived from human blastocysts. , 1998, Science.
[146] R. Thangavel,et al. Expression of markers for both neuronal and glial cells in human amniotic epithelial cells , 1996, Neuroscience Letters.
[147] M. Sharpe,et al. Scatter factor/hepatocyte growth factor is essential for liver development , 1995, Nature.
[148] Linda Lowe,et al. Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation , 1993, Nature.
[149] University of Zurich Zurich Open Repository and Archive , 2010 .
[150] Ye-Guang Chen. Endocytic regulation of TGF-β signaling , 2009, Cell Research.
[151] K. Miyazono,et al. Roles of TGF-β family signaling in stem cell renewal and differentiation , 2009, Cell Research.
[152] Marie-José Goumans,et al. TGF-β signaling in vascular biology and dysfunction , 2009, Cell Research.
[153] C. Hill. Nucleocytoplasmic shuttling of Smad proteins , 2009, Cell Research.
[154] David Padua,et al. Roles of TGFβ in metastasis , 2009, Cell Research.
[155] Charles C Hong,et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. , 2008, Nature chemical biology.
[156] W. Harris,et al. Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. , 2008, Developmental biology.
[157] H. Moses,et al. Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer? , 2008, Cancer research.
[158] D. Stolz,et al. Short communication Identification of stem cell marker-positive cells by immunofluorescence in term human amnion , 2007 .
[159] A. Moorman,et al. www.elsevier.com/locate/cardiores Review Role of bone morphogenetic proteins in cardiac differentiation , 2006 .
[160] D. Abrous,et al. Adult neurogenesis: from precursors to network and physiology. , 2005, Physiological reviews.
[161] M. Rudnicki,et al. Cellular and molecular regulation of muscle regeneration. , 2004, Physiological reviews.
[162] Y. Saijoh,et al. Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. , 2000, Molecular cell.