Subtype Analysis of Cryptosporidium Isolates From Children in Uganda

Cryptosporidium hominis and Cryptosporidium parvum isolates from children in Uganda were characterized by DNA sequence analysis of the GP60 gene. Eight alleles were identified, 4 C. hominis and 4 C. parvum, of which 3 represent new C. parvum families. The data show that it is highly likely that the route of transmission is anthroponotic.

[1]  S. Tzipori,et al.  Cryptosporidiosis and microsporidiosis in ugandan children with persistent diarrhea with and without concurrent infection with the human immunodeficiency virus. , 2005, The American journal of tropical medicine and hygiene.

[2]  S. Cacciò,et al.  Molecular epidemiology of human cryptosporidiosis. , 2005, Parassitologia.

[3]  I. Sulaiman,et al.  Unique Endemicity of Cryptosporidiosis in Children in Kuwait , 2005, Journal of Clinical Microbiology.

[4]  Michael P. Cummings,et al.  PAUP* [Phylogenetic Analysis Using Parsimony (and Other Methods)] , 2004 .

[5]  Lihua Xiao,et al.  Cryptosporidiosis: an update in molecular epidemiology , 2004, Current opinion in infectious diseases.

[6]  Una Ryan,et al.  Cryptosporidium Taxonomy: Recent Advances and Implications for Public Health , 2004, Clinical Microbiology Reviews.

[7]  T. Boonmars,et al.  Intraspecies Polymorphism of Cryptosporidium parvum Revealed by PCR-Restriction Fragment Length Polymorphism (RFLP) and RFLP-Single-Strand Conformational Polymorphism Analyses , 2003, Applied and Environmental Microbiology.

[8]  S. Meshnick,et al.  Molecular Epidemiology of Cryptosporidiosis in Children in Malawi , 2003, The Journal of eukaryotic microbiology.

[9]  S. Tzipori,et al.  Cryptosporidium parvum in children with diarrhea in Mulago Hospital, Kampala, Uganda. , 2003, The American journal of tropical medicine and hygiene.

[10]  F. Antunes,et al.  Subgenotype Analysis of Cryptosporidium Isolates from Humans, Cattle, and Zoo Ruminants in Portugal , 2003, Journal of Clinical Microbiology.

[11]  Xiao-Guang Chen,et al.  Analysis of the gene expression profile of Schistosoma japonicum cercariae by a strategy based on expressed sequence tags , 2003, Parasitology Research.

[12]  M. Wilson,et al.  Genetic diversity of Cryptosporidium spp. in cattle in Michigan: implications for understanding the transmission dynamics , 2003, Parasitology Research.

[13]  Z. Egyed,et al.  Characterization of Cryptosporidium spp.--recent developments and future needs. , 2003, Veterinary parasitology.

[14]  S. Tzipori,et al.  Genetic Analysis of a Cryptosporidium parvum Human Genotype 1 Isolate Passaged through Different Host Species , 2002, Infection and Immunity.

[15]  S. Tzipori,et al.  Cryptosporidiosis: biology, pathogenesis and disease. , 2002, Microbes and infection.

[16]  N. Rollins,et al.  Analysis of Sequence Diversity at the Highly Polymorphic Cpgp40/15 Locus among Cryptosporidium Isolates from Human Immunodeficiency Virus-Infected Children in South Africa , 2002, Infection and Immunity.

[17]  J. Dooley,et al.  Three Drinking-Water–Associated Cryptosporidiosis Outbreaks, Northern Ireland , 2002, Emerging infectious diseases.

[18]  J. Priest,et al.  The immunodominant 17-kDa antigen from Cryptosporidium parvum is glycosylphosphatidylinositol-anchored. , 2001, Molecular and biochemical parasitology.

[19]  S J Upton,et al.  Epidemiology of Cryptosporidium: transmission, detection and identification. , 2000, International journal for parasitology.

[20]  S. Tzipori,et al.  Molecular Cloning and Expression of a Gene EncodingCryptosporidium parvum Glycoproteins gp40 and gp15 , 2000, Infection and Immunity.

[21]  J. Gut,et al.  Cloning and Sequence Analysis of a Highly Polymorphic Cryptosporidium parvum Gene Encoding a 60-Kilodalton Glycoprotein and Characterization of Its 15- and 45-Kilodalton Zoite Surface Antigen Products , 2000, Infection and Immunity.

[22]  S. Tzipori,et al.  The biology of Cryptosporidium. , 2000, Contributions to microbiology.

[23]  J. Thompson,et al.  The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. , 1997, Nucleic acids research.

[24]  J. Thompson,et al.  CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. , 1994, Nucleic acids research.