Lumican deficiency promotes pulmonary arterial remodeling.
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W. Kao | Y. Yeh | Wei-Jan Chen | Ying-Ju Lai | P. Chu | Yung-Hsin Yeh
[1] J. Monboisse,et al. Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression , 2020, Frontiers in Oncology.
[2] Cheng-Ta Yang,et al. Downregulation of lumican accelerates lung cancer cell invasion through p120 catenin , 2018, Cell Death & Disease.
[3] J. Pang,et al. Prostanoid EP4 agonist L-902,688 activates PPARγ and attenuates pulmonary arterial hypertension. , 2018, American journal of physiology. Lung cellular and molecular physiology.
[4] Pin-i Chen,et al. Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-&bgr; in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension , 2017, Arteriosclerosis, thrombosis, and vascular biology.
[5] W. Kao,et al. Lumican Peptides: Rational Design Targeting ALK5/TGFBRI , 2017, Scientific Reports.
[6] Y. Yeh,et al. Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase , 2015, PloS one.
[7] J. Garcia,et al. Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension. , 2015, American journal of physiology. Lung cellular and molecular physiology.
[8] Huamin Wang,et al. Extracellular Lumican Inhibits Pancreatic Cancer Cell Growth and Is Associated with Prolonged Survival after Surgery , 2014, Clinical Cancer Research.
[9] N. Karamanos,et al. Lumican affects tumor cell functions, tumor-ECM interactions, angiogenesis and inflammatory response. , 2014, Matrix biology : journal of the International Society for Matrix Biology.
[10] W. Seeger,et al. Novel and emerging therapies for pulmonary hypertension. , 2014, American journal of respiratory and critical care medicine.
[11] S. Saika,et al. Lumican Binds ALK5 to Promote Epithelium Wound Healing , 2013, PloS one.
[12] W. Kao,et al. Lumican Exhibits Anti-Angiogenic Activity in a Context Specific Manner , 2013, Cancer Microenvironment.
[13] J. Dubois-Randé,et al. Rapamycin reverses pulmonary artery smooth muscle cell proliferation in pulmonary hypertension. , 2013, American journal of respiratory cell and molecular biology.
[14] H. Ghofrani,et al. Mechanisms of disease: pulmonary arterial hypertension , 2011, Nature Reviews Cardiology.
[15] P. Katonis,et al. Lumican regulates osteosarcoma cell adhesion by modulating TGFβ2 activity. , 2011, The international journal of biochemistry & cell biology.
[16] W. Kao,et al. Impaired skin wound healing in lumican‐null mice , 2010, The British journal of dermatology.
[17] E. K. Weir,et al. Basic Science of Pulmonary Arterial Hypertension for Clinicians: New Concepts and Experimental Therapies , 2010, Circulation.
[18] Chengqun Huang,et al. NOTCH3 SIGNALING IS REQUIRED FOR THE DEVELOPMENT OF PULMONARY ARTERIAL HYPERTENSION , 2009, Nature Medicine.
[19] N. Morrell,et al. Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension: Potential for Activin Receptor-Like Kinase-5 Inhibition in Prevention and Progression of Disease , 2009, Circulation.
[20] A. Tsatsakis,et al. Lumican, a small leucine‐rich proteoglycan , 2008, IUBMB life.
[21] W. Seeger,et al. Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension. , 2008, American journal of respiratory and critical care medicine.
[22] M. Rabinovitch. Molecular pathogenesis of pulmonary arterial hypertension. , 2008, The Journal of clinical investigation.
[23] S. Oparil,et al. Transforming growth factor-beta signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung. , 2008, American journal of physiology. Lung cellular and molecular physiology.
[24] P. Sehgal,et al. Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. , 2008, American journal of respiratory and critical care medicine.
[25] A. Tsatsakis,et al. Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells , 2008, The FEBS journal.
[26] T. Kietzmann,et al. Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells. , 2007, Molecular biology of the cell.
[27] W. Seeger,et al. Reversal of experimental pulmonary hypertension by PDGF inhibition. , 2005, The Journal of clinical investigation.
[28] Wei Li,et al. Soluble lumican glycoprotein purified from human amniotic membrane promotes corneal epithelial wound healing. , 2005, Investigative ophthalmology & visual science.
[29] G. Owens,et al. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. , 2004, Physiological reviews.
[30] F. Antonicelli,et al. The small leucine-rich proteoglycan lumican inhibits melanoma progression. , 2004, Experimental cell research.
[31] Ying E. Zhang,et al. Smad-dependent and Smad-independent pathways in TGF-β family signalling , 2003, Nature.
[32] N. Morrell,et al. Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension. , 2002, Progress in cardiovascular diseases.
[33] Reynold A Panettieri,et al. PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. , 2002, American journal of physiology. Lung cellular and molecular physiology.
[34] B. A. Austin,et al. Altered collagen fibril formation in the sclera of lumican-deficient mice. , 2002, Investigative ophthalmology & visual science.
[35] Y. Sugisaki,et al. Expression of lumican in thickened intima and smooth muscle cells in human coronary atherosclerosis. , 2002, Experimental and molecular pathology.
[36] T. Ishiwata,et al. Effects of the extracellular matrix on lumican expression in rat aortic smooth muscle cells in vitro , 2001, The Journal of pathology.
[37] R. Trembath,et al. Altered Growth Responses of Pulmonary Artery Smooth Muscle Cells From Patients With Primary Pulmonary Hypertension to Transforming Growth Factor-&bgr;1 and Bone Morphogenetic Proteins , 2001, Circulation.
[38] E. Takashi,et al. Expression and localization of lumican in the ischemic and reperfused rat heart. , 2001, Japanese circulation journal.
[39] J. Massagué,et al. TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders , 2000, Cell.
[40] S. Saika,et al. Role of Lumican in the Corneal Epithelium during Wound Healing* , 2000, The Journal of Biological Chemistry.
[41] D. Badesch,et al. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension. , 1999, American journal of respiratory and critical care medicine.
[42] P. Roughley,et al. Expression of lumican in human lungs. , 1998, American journal of respiratory cell and molecular biology.
[43] J. Hassell,et al. Regulation of corneal collagen fibrillogenesis in vitro by corneal proteoglycan (lumican and decorin) core proteins. , 1993, Experimental eye research.
[44] J. Hassell,et al. Isolation and partial characterization of lumican and decorin from adult chicken corneas. A keratan sulfate-containing isoform of decorin is developmentally regulated. , 1992, The Journal of biological chemistry.
[45] J. Vergnes,et al. cDNA to chick lumican (corneal keratan sulfate proteoglycan) reveals homology to the small interstitial proteoglycan gene family and expression in muscle and intestine. , 1992, The Journal of biological chemistry.
[46] G. Conrad,et al. Focus on molecules: lumican. , 2006, Experimental eye research.