Isolation rearing effects on probabilistic learning and cognitive flexibility in rats

[1]  J. Hagan,et al.  Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats , 2001, Psychopharmacology.

[2]  N. Swerdlow,et al.  Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies , 2001, Psychopharmacology.

[3]  T. Robbins,et al.  Measuring the construct of executive control in schizophrenia: Defining and validating translational animal paradigms for discovery research , 2013, Neuroscience & Biobehavioral Reviews.

[4]  K. J. Murphy,et al.  Peripubertal viral-like challenge and social isolation mediate overlapping but distinct effects on behaviour and brain interferon regulatory factor 7 expression in the adult Wistar rat , 2013, Brain, Behavior, and Immunity.

[5]  R. Dolan,et al.  Dopamine Enhances Model-Based over Model-Free Choice Behavior , 2012, Neuron.

[6]  C. Winstanley,et al.  Differential effects of environmental enrichment, social-housing, and isolation-rearing on a rat gambling task: Dissociations between impulsive action and risky decision-making , 2012, Psychopharmacology.

[7]  T. Robbins,et al.  Differential Contributions of the Primate Ventrolateral Prefrontal and Orbitofrontal Cortex to Serial Reversal Learning , 2010, The Journal of Neuroscience.

[8]  M. Geyer,et al.  Isolation rearing-induced deficits in contextual fear learning do not require CRF2 receptors , 2010, Behavioural Brain Research.

[9]  T. Robbins,et al.  Serotonin Modulates Sensitivity to Reward and Negative Feedback in a Probabilistic Reversal Learning Task in Rats , 2010, Neuropsychopharmacology.

[10]  Sl McLean,et al.  Isolation rearing impairs novel object recognition and attentional set shifting performance in female rats , 2010, Journal of psychopharmacology.

[11]  S. Powell Models of neurodevelopmental abnormalities in schizophrenia. , 2010, Current topics in behavioral neurosciences.

[12]  M. van den Buuse Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects. , 2010, Schizophrenia bulletin.

[13]  Martin P Paulus,et al.  A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. , 2009, Archives of general psychiatry.

[14]  Samuel B. Hutton,et al.  Discrimination Learning, Reversal, and Set-Shifting in First-Episode Schizophrenia: Stability Over Six Years and Specific Associations with Medication Type and Disorganization Syndrome , 2009, Biological Psychiatry.

[15]  P. Seeman,et al.  Increased dopamine D  2High receptors in rats reared in social isolation , 2009, Synapse.

[16]  R. Keefe,et al.  Psychosocial factors in the neurobiology of schizophrenia: a selective review. , 2009, Annals of the Academy of Medicine, Singapore.

[17]  D. Auer,et al.  Effects of social isolation rearing on the limbic brain: A combined behavioral and magnetic resonance imaging volumetry study in rats , 2009, Neuroscience.

[18]  B. Sahakian,et al.  Hot and cold cognition in unmedicated depressed subjects with bipolar disorder. , 2009, Bipolar disorders.

[19]  A. Chappell,et al.  Early social isolation in male Long-Evans rats alters both appetitive and consummatory behaviors expressed during operant ethanol self-administration. , 2009, Alcoholism, clinical and experimental research.

[20]  M. Frank,et al.  CNTRICS final task selection: long-term memory. , 2009, Schizophrenia bulletin.

[21]  Guy B. Williams,et al.  Neural basis of abnormal response to negative feedback in unmedicated mood disorders , 2008, NeuroImage.

[22]  K. Fone,et al.  Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders , 2008, Neuroscience & Biobehavioral Reviews.

[23]  E. T. Bullmore,et al.  Reinforcement and Reversal Learning in First-Episode Psychosis , 2008, Schizophrenia bulletin.

[24]  A. Holmes,et al.  Enhanced negative feedback responses in remitted depression , 2008, Neuroreport.

[25]  D. Penn,et al.  Social functioning in individuals at clinical high risk for psychosis , 2008, Schizophrenia Research.

[26]  Tyrone D. Cannon,et al.  Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. , 2008, Archives of general psychiatry.

[27]  Martin P. Paulus,et al.  A reverse-translational approach to bipolar disorder: Rodent and human studies in the Behavioral Pattern Monitor , 2007, Neuroscience & Biobehavioral Reviews.

[28]  Benjamin M. Robinson,et al.  Selective Reinforcement Learning Deficits in Schizophrenia Support Predictions from Computational Models of Striatal-Cortical Dysfunction , 2007, Biological Psychiatry.

[29]  James A. Waltz,et al.  Probabilistic reversal learning impairments in schizophrenia: Further evidence of orbitofrontal dysfunction , 2007, Schizophrenia Research.

[30]  T. Robbins,et al.  Effects of orbitofrontal, infralimbic and prelimbic cortical lesions on serial spatial reversal learning in the rat , 2007, Behavioural Brain Research.

[31]  Liang Li,et al.  Chronic administration of clozapine alleviates reversal-learning impairment in isolation-reared rats , 2007, Behavioural pharmacology.

[32]  J. Hagan,et al.  Isolation rearing induces recognition memory deficits accompanied by cytoskeletal alterations in rat hippocampus , 2006, The European journal of neuroscience.

[33]  A. Mortimer,et al.  Cognitive function and social abilities in patients with schizophrenia: Relationship with atypical antipsychotics , 2006, Psychiatry and clinical neurosciences.

[34]  M. Low,et al.  Differential Contributions of Dopamine D1, D2, and D3 Receptors to MDMA-Induced Effects on Locomotor Behavior Patterns in Mice , 2006, Neuropsychopharmacology.

[35]  G. Higgins,et al.  Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs , 1995, Psychopharmacology.

[36]  C. Reavill,et al.  Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats: an update , 2005, Psychopharmacology.

[37]  Michael F. Green,et al.  Identification of separable cognitive factors in schizophrenia , 2004, Schizophrenia Research.

[38]  V. Brown,et al.  Double dissociation of social and environmental stimulation on spatial learning and reversal learning in rats , 2004, Behavioural Brain Research.

[39]  M. Olmstead,et al.  Adolescent enrichment partially reverses the social isolation syndrome. , 2004, Brain research. Developmental brain research.

[40]  M. Farah,et al.  Ventromedial frontal cortex mediates affective shifting in humans: evidence from a reversal learning paradigm. , 2003, Brain : a journal of neurology.

[41]  T. Robbins,et al.  Neuropsychological impairment in patients with major depressive disorder: the effects of feedback on task performance , 2003, Psychological Medicine.

[42]  T. Sharma,et al.  Cognitive function in schizophrenia. Deficits, functional consequences, and future treatment. , 2003, The Psychiatric clinics of North America.

[43]  T. Robbins,et al.  Specific abnormalities in serotonin release in the prefrontal cortex of isolation-reared rats measured during behavioural performance of a task assessing visuospatial attention and impulsivity , 2002, Psychopharmacology.

[44]  N. Swerdlow,et al.  Isolation rearing-induced deficits in prepulse inhibition and locomotor habituation are not potentiated by water deprivation , 2002, Physiology & Behavior.

[45]  Thomas E. Smith,et al.  Cognitive functioning and social problem-solving skills in schizophrenia , 2002, Cognitive neuropsychiatry.

[46]  Sheri L. Johnson,et al.  Responsiveness to Threat and Incentive in Bipolar Disorder: Relations of the BIS/BAS Scales with Symptoms , 2001, Journal of psychopathology and behavioral assessment.

[47]  H. Würbel,et al.  Early social deprivation disrupts attentional, but not affective, shifts in rats. , 2001, Behavioral neuroscience.

[48]  J. Feldon,et al.  Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome , 2000, Neuroscience.

[49]  C. Marsden,et al.  Effects of noradrenaline depletion in the brain on response to novelty in isolation-reared rats , 2000, Psychopharmacology.

[50]  T. Robbins,et al.  Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression , 2000, Psychopharmacology.

[51]  M. Geyer,et al.  Environmental enrichment and isolation rearing in the rat: effects on locomotor behavior and startle response plasticity , 2000, Biological Psychiatry.

[52]  T. Goldberg,et al.  Cognitive impairment in schizophrenia is the core of the disorder. , 2000, Critical reviews in neurobiology.

[53]  P. Møller,et al.  The initial prodrome in schizophrenia: searching for naturalistic core dimensions of experience and behavior. , 2000, Schizophrenia bulletin.

[54]  M. Geyer,et al.  Ontogeny of Isolation Rearing-Induced Deficits in Sensorimotor Gating in Rats , 1999, Physiology & Behavior.

[55]  W. Heiden,et al.  Depression, negative symptoms, social stagnation and social decline in the early course of schizophrenia , 1999, Acta psychiatrica Scandinavica.

[56]  B. Lerer,et al.  Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia , 1999, Molecular Psychiatry.

[57]  M. Geyer,et al.  Effects of isolation rearing on startle reactivity, habituation, and prepulse inhibition in male Lewis, Sprague-Dawley, and Fischer F344 rats. , 1998, Behavioral neuroscience.

[58]  M. Linnoila,et al.  Effects of isolation-rearing on locomotion, anxiety and responses to ethanol in Fawn Hooded and Wistar rats , 1998, Psychopharmacology.

[59]  Martin P. Paulus,et al.  Isolation rearing affects sequential organization of motor behavior in post-pubertal but not pre-pubertal Lister and Sprague–Dawley rats , 1998, Behavioural Brain Research.

[60]  N. Swerdlow,et al.  Reversal of Isolation Rearing-Induced Deficits in Prepulse Inhibition by Seroquel and Olanzapine , 1998, Biological Psychiatry.

[61]  C. Marsden,et al.  Effect of Isolation‐Rearing on Conditioned Dopamine Release In Vivo in the Nucleus Accumbens of the Rat , 1998, Journal of neurochemistry.

[62]  F. Hall,et al.  Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioral consequences. , 1998, Critical reviews in neurobiology.

[63]  A. Mortimer Cognitive Function in Schizophrenia— Do Neuroleptics Make a Difference? , 1997, Pharmacology Biochemistry and Behavior.

[64]  C. Marsden,et al.  Effects of social isolation rearing on learning in the morris water maze , 1996, Brain Research.

[65]  T. Robbins,et al.  Behavioural and neurochemical effects of early social deprivation in the rat , 1996, Journal of psychopharmacology.

[66]  T. Robbins,et al.  Social Isolation in the Rat Produces Developmentally Specific Deficits in Prepulse Inhibition of the Acoustic Startle Response Without Disrupting Latent Inhibition , 1994, Neuropsychopharmacology.

[67]  Trevor W. Robbins,et al.  Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia , 1993, Biological Psychiatry.

[68]  T. Robbins,et al.  Dopaminergic and serotonergic function following isolation rearing in rats: Study of behavioural responses and postmortem and in vivo neurochemistry , 1992, Pharmacology Biochemistry and Behavior.

[69]  Christian Grillon,et al.  Gating and habituation of the startle reflex in schizophrenic patients. , 1992 .

[70]  G. Mogenson,et al.  Quinpirole to the accumbens reduces exploratory and amphetamine-elicited locomotion , 1991, Brain Research Bulletin.

[71]  T. Robbins,et al.  Behavioural rigidity and rule-learning deficits following isolation-rearing in the rat: neurochemical correlates , 1991, Behavioural Brain Research.

[72]  J. Becker,et al.  Psychosocial Aspects of Depression , 1991 .

[73]  R. Morice Cognitive Inflexibility and Pre-frontal Dysfunction in Schizophrenia and Mania , 1990, British Journal of Psychiatry.

[74]  T. Barnes,et al.  Cognitive functioning and symptomatology in chronic schizophrenia , 1990, Schizophrenia Research.

[75]  D L Braff,et al.  Sensorimotor gating and schizophrenia. Human and animal model studies. , 1990, Archives of general psychiatry.

[76]  T. Robbins,et al.  Isolation-rearing retards the acquisition of schedule-induced polydipsia in rats , 1989, Physiology & Behavior.

[77]  I. Gotlib,et al.  Psychosocial functioning and depression: distinguishing among antecedents, concomitants, and consequences. , 1988, Psychological bulletin.

[78]  A. Nikonov [The isolation syndrome]. , 1988, Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova.

[79]  T. Goldberg,et al.  Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test. , 1987, Archives of general psychiatry.

[80]  D. Weinberger Implications of normal brain development for the pathogenesis of schizophrenia. , 1987, Archives of general psychiatry.

[81]  Patrick V. Russo,et al.  Multivariate assessment of locomotor behavior: Pharmacological and behavioral analyses , 1986, Pharmacology Biochemistry and Behavior.

[82]  G. Mogenson,et al.  Neuropharmacological evidence to suggest that the nucleus accumbens and subpallidal region contribute to exploratory locomotion. , 1984, Behavioral and neural biology.

[83]  S. Ahlénius,et al.  Suppression of exploratory locomotor activity in the rat by the local application of 3-PPP enantiomers into the nucleus accumbens. , 1983, European journal of pharmacology.

[84]  J. Glowinski,et al.  Response to stress of mesocortico-frontal dopaminergic neurones in rats after long-term isolation , 1980, Nature.

[85]  M. Geyer,et al.  Prestimulus effects on human startle reflex in normals and schizophrenics. , 1978, Psychophysiology.

[86]  M. Morgan,et al.  The effects of psychomotor stimulants on stereotypy and locomotor activity in socially-deprived and control rats , 1975, Brain Research.

[87]  J. Warren Reversal learning and the formation of learning sets by cats and rhesus monkeys. , 1966, Journal of Comparative and Physiological Psychology.

[88]  E. Bennett,et al.  Relations between chemistry and problem-solving among rats raised in enriched and impoverished environments. , 1962, Journal of comparative and physiological psychology.