Genetic and structural analysis of the protein stability problem.
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[1] B. Matthews,et al. Temperature-sensitive mutations of bacteriophage T4 lysozyme occur at sites with low mobility and low solvent accessibility in the folded protein. , 1987, Biochemistry.
[2] T. Poulos,et al. Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond. , 1987, Biochemistry.
[3] N. Xuong,et al. An engineered disulfide bond in dihydrofolate reductase. , 1987, Biochemistry.
[4] H M Holden,et al. Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond. , 1987, Science.
[5] P. Bartlett,et al. Evaluation of intrinsic binding energy from a hydrogen bonding group in an enzyme inhibitor. , 1987, Science.
[6] Tadayuki Imanaka,et al. A new way of enhancing the thermostability of proteases , 1986, Nature.
[7] R. Sauer,et al. Bacteriophage lambda cro mutations: effects on activity and intracellular degradation. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[8] A. Kossiakoff,et al. The crystallographically determined structures of atypical strained disulfides engineered into subtilisin. , 1986, The Journal of biological chemistry.
[9] C. Pabo,et al. Computer-aided model-building strategies for protein design. , 1986, Biochemistry.
[10] R. Sauer,et al. An engineered intersubunit disulfide enhances the stability and DNA binding of the N-terminal domain of lambda repressor. , 1986, Biochemistry.
[11] D. Powers,et al. In vivo formation and stability of engineered disulfide bonds in subtilisin. , 1986, The Journal of biological chemistry.
[12] T. Mckenzie,et al. Isolation of a thermostable enzyme variant by cloning and selection in a thermophile. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[13] R. Sauer,et al. Stabilization of λ repressor against thermal denaturation by site‐directed Gly→Ala changes in α‐helix 3 , 1986 .
[14] R. L. Baldwin,et al. The design and production of semisynthetic ribonucleases with increased thermostability by incorporation of S‐peptide analogues with enhanced helical stability , 1986, Proteins.
[15] M. Matsumura,et al. Screening for thermostable mutant of kanamycin nucleotidyltransferase by the use of a transformation system for a thermophile, Bacillus stearothermophilus. , 1985, The Journal of biological chemistry.
[16] D. Shortle,et al. Genetic analysis of staphylococcal nuclease: identification of three intragenic "global" suppressors of nuclease-minus mutations. , 1985, Genetics.
[17] J. A. Wozniak,et al. A genetic screen for mutations that increase the thermal stability of phage T4 lysozyme. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[18] L. J. Perry,et al. Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation. , 1984, Science.
[19] J. Kraut,et al. Directed mutagenesis of dihydrofolate reductase. , 1983, Science.
[20] T. Creighton. An empirical approach to protein conformation stability and flexibility , 1983, Biopolymers.
[21] B. Matthews,et al. Molecular basis of thermostability in the lysozyme from bacteriophage T4 , 1979, Nature.
[22] H. Berendsen,et al. The α-helix dipole and the properties of proteins , 1978, Nature.
[23] B. Matthews. X-ray Crystallographic Studies of Proteins , 1976 .
[24] A. Bellocq,et al. [Conformation analysis of L-pyroglutamic acid N-methylamide by depolarized Rayleigh diffusion, vibration spectroscopy, and conformational energy calculation]. , 1975, Biopolymers.
[25] B. Matthews,et al. The conformation of thermolysin. , 1974, The Journal of biological chemistry.
[26] M. Matsumura,et al. Cumulative effect of intragenic amino-acid replacements on the thermostability of a protein , 1986, Nature.
[27] J. Richardson,et al. The anatomy and taxonomy of protein structure. , 1981, Advances in protein chemistry.
[28] M. Goodman,et al. Mechanisms of protein and polypeptide helix initiation , 1975 .
[29] W. Dreyer,et al. Mutations affecting the lysozyme of phage T4. , 1961, Cold Spring Harbor symposia on quantitative biology.