Dissecting the role of aberrant DNA methylation in human leukemia

[1]  Nathan C. Sheffield,et al.  Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1 , 2015, Cell reports.

[2]  Thomas Lengauer,et al.  Comprehensive Analysis of DNA Methylation Data with RnBeads , 2014, Nature Methods.

[3]  G. Carmichael,et al.  Innate Immunity in Pluripotent Human Cells , 2013, The Journal of Biological Chemistry.

[4]  S. Armstrong,et al.  Cell of origin determines clinically relevant subtypes of MLL-rearranged AML , 2013, Leukemia.

[5]  Paul Bertone,et al.  Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner. , 2013, Genes & development.

[6]  D. Neuberg,et al.  In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells. , 2013, Blood.

[7]  T. Stopka,et al.  Role of Epigenetics in Chronic Myeloid Leukemia , 2013, Current Hematologic Malignancy Reports.

[8]  Thomas Lengauer,et al.  EpiExplorer: live exploration and global analysis of large epigenomic datasets , 2012, Genome Biology.

[9]  C. Bock Analysing and interpreting DNA methylation data , 2012, Nature Reviews Genetics.

[10]  P. Laird,et al.  Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data , 2012, Genome Biology.

[11]  G. Reifenberger,et al.  IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics , 2012, Nature.

[12]  P. Laird,et al.  Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data , 2012, Genome Biology.

[13]  Shiaw-Min Hwang,et al.  Defective Antiviral Responses of Induced Pluripotent Stem Cells to Baculoviral Vector Transduction , 2012, Journal of Virology.

[14]  Manolis Kellis,et al.  ChromHMM: automating chromatin-state discovery and characterization , 2012, Nature Methods.

[15]  J. Radich,et al.  IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. , 2011, Cancer cell.

[16]  Nianxiang Zhang,et al.  Aberrant DNA Methylation Is Associated with Disease Progression, Resistance to Imatinib and Shortened Survival in Chronic Myelogenous Leukemia , 2011, PloS one.

[17]  R. Stewart,et al.  Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells , 2011, Nature.

[18]  H. Aburatani,et al.  Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. , 2010, Blood.

[19]  Natalie Jäger,et al.  Genome-wide mapping of DNA methylation: a quantitative technology comparison , 2010, Nature Biotechnology.

[20]  G. Carmichael,et al.  Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells , 2010, Cell cycle.

[21]  R. Siebert,et al.  DNA Methylation Profiles and Their Relationship with Cytogenetic Status in Adult Acute Myeloid Leukemia , 2010, PloS one.

[22]  Martin J. Aryee,et al.  Epigenetic memory in induced pluripotent stem cells , 2010, Nature.

[23]  J. Qian,et al.  Methylation status of DDIT3 gene in Chronic Myeloid Leukemia , 2010, Journal of experimental & clinical cancer research : CR.

[24]  R. Jaenisch,et al.  Generation of iPSCs from cultured human malignant cells. , 2010, Blood.

[25]  Fabien Campagne,et al.  DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. , 2010, Cancer cell.

[26]  Zachary D. Smith,et al.  Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution , 2010, Nature Methods.

[27]  K. Mimori,et al.  Defined factors induce reprogramming of gastrointestinal cancer cells , 2009, Proceedings of the National Academy of Sciences.

[28]  R. Månsson,et al.  Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML. , 2009, Cancer cell.

[29]  Wei Li,et al.  BSMAP: whole genome bisulfite sequence MAPping program , 2009, BMC Bioinformatics.

[30]  G. Daley,et al.  Generation of induced pluripotent stem cells from human blood. , 2009, Blood.

[31]  Alexander Meissner,et al.  Induced pluripotent stem cells: current progress and potential for regenerative medicine. , 2009, Trends in molecular medicine.

[32]  T. Mikkelsen,et al.  Dissecting direct reprogramming through integrative genomic analysis , 2008, Nature.

[33]  T. Ichisaka,et al.  Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.

[34]  T. Graf Faculty Opinions recommendation of Induction of pluripotent stem cells from adult human fibroblasts by defined factors. , 2007 .

[35]  Robert Brown,et al.  Inactivation of HOXA Genes by Hypermethylation in Myeloid and Lymphoid Malignancy is Frequent and Associated with Poor Prognosis , 2007, Clinical Cancer Research.

[36]  Zohar Yakhini,et al.  Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer , 2007, Nature Genetics.

[37]  Kelly M. McGarvey,et al.  A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing , 2007, Nature Genetics.

[38]  Thomas Lengauer,et al.  BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing , 2005, Bioinform..

[39]  J. Thomson,et al.  Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. , 2005, Blood.

[40]  J. Kutok,et al.  Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1 , 2004, Nature Genetics.

[41]  Gordon K Smyth,et al.  Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .

[42]  A. Feinberg,et al.  The history of cancer epigenetics , 2004, Nature Reviews Cancer.

[43]  J. Herman,et al.  Gene silencing in cancer in association with promoter hypermethylation. , 2003, The New England journal of medicine.

[44]  Long-Cheng Li,et al.  MethPrimer: designing primers for methylation PCRs , 2002, Bioinform..

[45]  G. Daley,et al.  The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. , 1986, Science.

[46]  Daniel J Brat,et al.  Molecular genetics of gliomas. , 2014, Cancer journal.

[47]  F. H. Garrison The history of cancer. , 2012, Bulletin of the New York Academy of Medicine.

[48]  A. Feinberg,et al.  The epigenetic progenitor origin of human cancer , 2006, Nature Reviews Genetics.

[49]  B. Göttgens,et al.  Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis. , 2005, Blood.

[50]  M. Baccarani,et al.  Real-time quantification of different types of bcr-abl transcript in chronic myeloid leukemia. , 2001, Haematologica.