论文信息 - A low cost, handheld E-nose for renal diseases early diagnosis

A low cost, handheld E-nose for renal diseases early diagnosis

In the last decade, the use of electronic olfaction systems for the early diagnosis of several pathologies by breath analysis has been investigated. In this study, an electronic nose including seven polyaniline sensors has been developed. An impedance measurement circuit and a micro-computer to process the sensor responses were studied to give a pre-diagnosis conclusion. The measurement accuracy is 97% when the E-nose is exposed to a simulated human breath and different concentration of ammonia, from 500 ppb to 2.8 ppm. The described prototype weights about 300 g and can be used for 14 hours with a smartphone battery.

[1] Kea-Tiong Tang,et al. Towards a fully integrated electronic nose SoC , 2012, 2012 IEEE 55th International Midwest Symposium on Circuits and Systems (MWSCAS).

[2] R. Aiyer,et al. Biopolymer-Polyaniline Composite for a Wide Range Ammonia Gas Sensor , 2016, IEEE Sensors Journal.

[3] David Smith,et al. A longitudinal study of methanol in the exhaled breath of 30 healthy volunteers using selected ion flow tube mass spectrometry, SIFT-MS , 2006, Physiological measurement.

[4] M. Phillips,et al. Variation in volatile organic compounds in the breath of normal humans. , 1999, Journal of chromatography. B, Biomedical sciences and applications.

[5] Zulfiqur Ali,et al. Data analysis for electronic nose systems , 2006 .

[6] Nathalie Redon,et al. Ultra sensitive ammonia sensors based on microwave synthesized nanofibrillar polyanilines , 2014 .

[7] P. Španěl,et al. Quantitative analysis of ammonia on the breath of patients in end-stage renal failure. , 1997, Kidney international.

[8] Ameen Abu-Hanna,et al. Comparison of classification methods in breath analysis by electronic nose , 2015, Journal of breath research.

[9] David Zhang,et al. Feature selection and analysis on correlated gas sensor data with recursive feature elimination , 2015 .

[10] Nathalie Redon,et al. The PANI-DBSA content and dispersing solvent as influencing parameters in sensing performances of TiO2/PANI-DBSA hybrid nanocomposites to ammonia , 2016 .