The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo.
暂无分享,去创建一个
Reuven Agami | Thomas Tuschl | Cameron Brennan | C. Brennan | T. Tuschl | J. Huse | R. Agami | E. Holland | C. le Sage | D. Hambardzumyan | S. Rouhanifard | B. Wee | Eric C Holland | Dolores Hambardzumyan | Carlos le Sage | Jason T Huse | Boyoung Wee | John Pena | Sara H Rouhanifard | Cherin Sohn-Lee | John T. G. Pena | Cherin Sohn-Lee | Carlos le Sage
[1] M. Zavolan,et al. miRNA in situ hybridization in formaldehyde and EDC–fixed tissues , 2009, Nature Methods.
[2] K. Kosik,et al. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. , 2005, Cancer research.
[3] Shuomin Zhu,et al. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis , 2008, Cell Research.
[4] D. Louis,et al. The retinoblastoma gene is involved in malignant progression of astrocytomas , 1994, Annals of neurology.
[5] Phillip D. Zamore,et al. Ribo-gnome: The Big World of Small RNAs , 2005, Science.
[6] Claudia Petritsch,et al. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells , 2008 .
[7] J. Pollack,et al. MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. , 2008, Blood.
[8] B. Scheithauer,et al. The 2007 WHO classification of tumours of the central nervous system , 2007, Acta Neuropathologica.
[9] G. Maira,et al. Regulation of the p 27 Kip 1 tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation , 2007 .
[10] Yunqing Li,et al. microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. , 2008, Cancer research.
[11] C. Croce,et al. MicroRNA signatures in human cancers , 2006, Nature Reviews Cancer.
[12] D. Bartel. MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.
[13] J. Baehring. An update on oligodendroglial neoplasms , 2005, Current opinion in neurology.
[14] R. Henkelman,et al. High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. , 2006, Cancer research.
[15] Shuomin Zhu,et al. MicroRNA-21 Targets the Tumor Suppressor Gene Tropomyosin 1 (TPM1)* , 2007, Journal of Biological Chemistry.
[16] D. Louis. WHO classification of tumours of the central nervous system , 2007 .
[17] H. Varmus,et al. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. , 1998, Genes & development.
[18] T. Dalmay,et al. MicroRNAs and cancer , 2008, Journal of internal medicine.
[19] C. Burge,et al. Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.
[20] T. Wurdinger,et al. MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators , 2008, Molecular and Cellular Biology.
[21] M. Rosenblum,et al. Dose-Dependent Effects of Platelet-Derived Growth Factor-B on Glial Tumorigenesis , 2004, Cancer Research.
[22] D. Louis,et al. PTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosis. , 2001, The American journal of pathology.
[23] G. Maira,et al. Extensive modulation of a set of microRNAs in primary glioblastoma. , 2005, Biochemical and biophysical research communications.
[24] N. Rajewsky,et al. Widespread changes in protein synthesis induced by microRNAs , 2008, Nature.
[25] C. Burge,et al. Prediction of Mammalian MicroRNA Targets , 2003, Cell.
[26] M. Berger,et al. Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma. , 2007, Neuro-oncology.
[27] P. Pandolfi,et al. PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. , 2008, Genes & development.
[28] L. Chin,et al. Malignant astrocytic glioma: genetics, biology, and paths to treatment. , 2007, Genes & development.
[29] P. Pandolfi,et al. mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma. , 2005, Neoplasia.
[30] Ralph Weissleder,et al. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. , 2007, Cancer research.
[31] T. Glover,et al. Mechanisms of common fragile site instability. , 2005, Human molecular genetics.
[32] D. Bartel,et al. The impact of microRNAs on protein output , 2008, Nature.
[33] Chung F. Wong,et al. MicroRNA-26a Targets the Histone Methyltransferase Enhancer of Zeste homolog 2 during Myogenesis* , 2008, Journal of Biological Chemistry.
[34] P. Platzer,et al. Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome. , 2008, American journal of human genetics.
[35] R. Mason,et al. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. , 2008, Cancer research.
[36] H. Varmus,et al. Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[37] Alice Shapiro,et al. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. , 2008, Cancer research.
[38] J. Uhm. An Integrated Genomic Analysis of Human Glioblastoma Multiforme , 2009 .
[39] Joshua M. Korn,et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways , 2008, Nature.
[40] C. James,et al. Molecular Genetics of Tumors of the Central Nervous System , 2005 .
[41] G. Peters,et al. Regulation of the INK4b–ARF–INK4a tumour suppressor locus: all for one or one for all , 2006, Nature Reviews Molecular Cell Biology.
[42] C. James,et al. PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. , 2001, Journal of the National Cancer Institute.
[43] C. Cordon-Cardo,et al. Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas. , 2008, Cancer research.
[44] P. Humphrey,et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[45] A. Donfrancesco,et al. Deregulated expression of miR-26a and Ezh2 in Rhabdomyosarcoma , 2009, Cell cycle.
[46] D. Louis,et al. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. , 2001, Genes & development.
[47] C. Croce,et al. MicroRNA gene expression deregulation in human breast cancer. , 2005, Cancer research.
[48] C. Croce,et al. A microRNA expression signature of human solid tumors defines cancer gene targets , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[49] K. Ghoshal,et al. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. , 2007, Gastroenterology.
[50] Huan Yang,et al. MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. , 2008, Cancer research.
[51] Reuven Agami,et al. Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation , 2007 .
[52] H. Horvitz,et al. MicroRNA expression profiles classify human cancers , 2005, Nature.
[53] M. Brandi,et al. Osteogenic Differentiation of Human Adipose Tissue‐Derived Stem Cells Is Modulated by the miR‐26a Targeting of the SMAD1 Transcription Factor , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[54] Yuri Kotliarov,et al. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. , 2008, Cancer cell.
[55] M. Weller,et al. PTEN methylation and expression in glioblastomas , 2003, Acta Neuropathologica.
[56] Reuven Agami,et al. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. , 2006, Cell.