Comparative Accuracy of Electrocardiographic and Vectorcardiographic Criteria for Inferior Myocardial Infarction

Numerous criteria for the diagnosis of inferior wall myocardial infarction by electrocardiogram (ECG) and vectorcardiogram (VCG) have been published, but they have not been subjected to a systematic, independent evaluation. Accordingly, we studied 146 patients undergoing cardiac catheterization; 63 were normal and 83 had a history of infarction, a significant right coronary lesion and an inferior wall motion abnormality (inferior infarction group). No ECG or VCG criteria were considered in the designation of the two groups; rather, three sets of ECG and VCG criteria were evaluated for this purpose. Specificity was excellent (98–100%) and sensitivity was poor (4–34%) by all three sets of ECG criteria, but the 1949 ECG criteria of Meyers et al. are the least sensitive (4%, p < 0.001). Specificity (90–100%) and sensitivity (82–84%) were very good by all three VCG criteria. The VCG criteria of Starr et al. gave no false-positive results in our normal group. Because of enhanced sensitivity, the overall accuracy of the VCG was higher than that of the ECG for the diagnosis of inferior infarction (90% vs 62%, p < 0.001). We conclude that more recent ECG criteria for the diagnosis of inferior wall myocardial infarction are highly specific, but insensitive compared with VCG criteria.

[1]  P. Stein,et al.  Vectorcardiographic diagnosis of diaphragmatic myocardial infarction. , 1976, The American journal of cardiology.

[2]  J. Greenfield,et al.  Evaluation of Vectorcardiographic Criteria for the Diagnosis of Myocardial Infarction in the Presence of Left Ventricular Hypertrophy , 1976, Circulation.

[3]  F. Yates Contingency Tables Involving Small Numbers and the χ2 Test , 1934 .

[4]  R. Helfant,et al.  Q waves and ventricular asynergy: predictive value and hemodynamic significance of anatomic localization. , 1975, The American journal of cardiology.

[5]  R. Galen Predictive value of laboratory tests , 1975 .

[6]  M. Scheinman,et al.  Nondiagnostic electrocardiogram in patients with acute myocardial infarction. Clinical and anatomic correlations. , 1973, The American journal of medicine.

[7]  A. Benchimol,et al.  Correlation of electrocardiogram and vectorcardiogram with coronary occlusion and myocardial contraction abnormality. , 1976, The American journal of cardiology.

[8]  T. Ryan,et al.  Predictive value of electrocardiographic patterns in localizing left ventricular asynergy in coronary artery disease. , 1979, American heart journal.

[9]  M. P. Judkins,et al.  Selective coronary arteriography. I. A percutaneous transfemoral technic. , 1967, Radiology.

[10]  T. Walsh,et al.  The vectorcardiographic QRS-sE-loop findings in inferoposterior myocardial infarction. , 1962, American heart journal.

[11]  G. B. Myers,et al.  Correlation of electrocardiographic and pathologic findings in anteroposterior infarction. , 1949, American heart journal.

[12]  E. Young,et al.  The Frontal Plane Vectorcardiogram in Old Inferior Myocardial Infarction: Criteria for Diagnosis and Electrocardiographic Correlation , 1968, Circulation.

[13]  H. Abramson The frontal plane QRS loop in the normal heart and in diaphragmatic myocardial infarction. , 1963, Canadian Medical Association journal.

[14]  R E Smith,et al.  Comparative Quantitative Analysis of the Electrocardiogram and the Vectorcardiogram: Correlations with the Coronary Arteriogram , 1970, Circulation.

[15]  G. B. Myers,et al.  Correlation of electrocardiographic and pathologic findings in posterior infarction. , 1949, American heart journal.

[16]  M. P. Judkins,et al.  Selective Coronary Arteriography , 1967 .

[17]  B. J. Winer,et al.  Statistical Principles in Experimental Design, 2nd Edition. , 1973 .

[18]  R. E. Smith,et al.  Vectorcardiographic identification of myocardial scar: a discriminative study with automatically processed vectorcardiographic information. , 1978, Journal of electrocardiology.

[19]  The electrocardiogram and vectorcardiogram in the diagnosis of the old inferior myocardial infarction. , 1973, Journal of electrocardiology.

[20]  J. Greenfield,et al.  Vectorcardiographic Criteria for the Diagnosis of Inferior Myocardial Infarction , 1974, Circulation.

[21]  E. Amsterdam,et al.  Electrocardiographic and Cineangiographic Correlations in Assessment of the Location, Nature and Extent of Abnormal Left Ventricular Segmental Contraction in Coronary Artery Disease , 1974, Circulation.

[22]  R. Helfant,et al.  The effect of severity of coronary artery obstructive disease and the coronary collateral circulation on local histopathologic and electrographic observations in man. , 1977, The American journal of medicine.

[23]  R. Helfant,et al.  Determination of lead III Q waves significance. Utility of deep inspiration. , 1977, Archives of internal medicine.

[24]  K. Lee,et al.  Evaluation of Asynergy As an Indicator of Myocardial Fibrosis , 1978, Circulation.

[25]  R. Ideker,et al.  Correlation of Postmortem Anatomic Findings with Electrocardiographic Changes in Patients with Myocardial Infarction: Retrospective Study of Patients with Typical Anterior and Posterior Infarcts , 1977, Circulation.

[26]  R Gorlin,et al.  Implications of left ventricular asynergy. , 1969, The American journal of cardiology.

[27]  C. L. Harris,et al.  Resting electrocardiogram in major coronary artery disease. , 1973, JAMA.

[28]  B. Sobel,et al.  Quantification of serum creatine phosphokinase isoenzyme activity. , 1974, The American journal of cardiology.