Integrated optical sensors based on refractometry of ion-selective membranes

Abstract The properties of optode membranes to be used for realizing miniature integrated optical sensors based on refractometry have been investigated theoretically and experimentally. In situ referencing by using optode and reference membranes on the same chip is a powerful means to discriminate against unspecific effects. The plasticized polymer membranes provide the function of selective extraction and chemical recognition of the analyte. In experiments performed for a pair of such membranes, refractive index differences ≈3 × 10 −3 per decade of molar Ca 2+ concentration in buffered aqueous solutions have been observed. With the characterized type of sensing pad implanted in a miniature integrated optical device, a typical overall resolution of 0.7 to 0.07% in units of Ca 2+ concentration was calculated.

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