Hypothermia mediates age-dependent increase of tau phosphorylation in db/db mice

[1]  L. Buée,et al.  Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms , 2015, Scientific Reports.

[2]  S. Hébert,et al.  Specificity of Anti-Tau Antibodies when Analyzing Mice Models of Alzheimer's Disease: Problems and Solutions , 2014, PloS one.

[3]  F. Wang,et al.  O-GlcNAcylation under hypoxic conditions and its effects on the blood-retinal barrier in diabetic retinopathy. , 2014, International journal of molecular medicine.

[4]  M. Garcia-Alloza,et al.  Central Proliferation and Neurogenesis Is Impaired in Type 2 Diabetes and Prediabetes Animal Models , 2014, PloS one.

[5]  A. Bretteville,et al.  Insulin dysfunction and Tau pathology , 2013, Front. Cell. Neurosci..

[6]  K. Chung,et al.  Age-dependent increases in tau phosphorylation in the brains of type 2 diabetic rats correlate with a reduced expression of p62 , 2013, Experimental Neurology.

[7]  S. Lovestone,et al.  The Importance of Tau Phosphorylation for Neurodegenerative Diseases , 2013, Front. Neurol..

[8]  L. Petrucelli,et al.  Does Obesity-Induced τ Phosphorylation Tip the Scale Toward Dementia? , 2013, Diabetes.

[9]  L. Buée,et al.  Detrimental Effects of Diet-Induced Obesity on τ Pathology Are Independent of Insulin Resistance in τ Transgenic Mice , 2013, Diabetes.

[10]  S. Hébert,et al.  Deregulation of Protein Phosphatase 2A and Hyperphosphorylation of τ Protein Following Onset of Diabetes in NOD Mice , 2013, Diabetes.

[11]  Muxun Zhang,et al.  Role of stereotaxically injected IgG from db/db mice in the phosphorylation of the microtubule-associated protein tau in hippocampus , 2012, Brain Research.

[12]  Wenli Sheng,et al.  Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice , 2012, Pharmacology Biochemistry and Behavior.

[13]  M. Novák,et al.  Tau truncation is a productive posttranslational modification of neurofibrillary degeneration in Alzheimer's disease. , 2010, Current Alzheimer research.

[14]  Eva L Feldman,et al.  Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes. , 2009, Endocrinology.

[15]  J. Götz,et al.  Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease , 2009, PloS one.

[16]  I. Grundke‐Iqbal,et al.  Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. , 2009, The American journal of pathology.

[17]  I. Grundke‐Iqbal,et al.  Brain glucose transporters, O‐GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer’s disease , 2009, Journal of neurochemistry.

[18]  J. Moriguti,et al.  (Pre)diabetes, brain aging, and cognition. , 2009, Biochimica et biophysica acta.

[19]  E. Masliah,et al.  Defective insulin signaling pathway and increased glycogen synthase kinase‐3 activity in the brain of diabetic mice: Parallels with Alzheimer's disease and correction by insulin , 2008, Journal of neuroscience research.

[20]  J. Luchsinger,et al.  Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms , 2007, The Journal of Neuroscience.

[21]  A. Sima,et al.  Alzheimer-Like Changes in Rat Models of Spontaneous Diabetes , 2007, Diabetes.

[22]  R. Nelson,et al.  Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia , 2007, The Journal of Neuroscience.

[23]  A. Zmijewska,et al.  Tau Is Hyperphosphorylated at Multiple Sites in Mouse Brain In Vivo After Streptozotocin-Induced Insulin Deficiency , 2006, Diabetes.

[24]  H. Braak,et al.  Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry , 2006, Acta Neuropathologica.

[25]  Fei Liu,et al.  Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation , 2005, The European journal of neuroscience.

[26]  L S Honig,et al.  Aggregation of vascular risk factors and risk of incident Alzheimer disease , 2005, Neurology.

[27]  K. Duff,et al.  Untangling memory deficits , 2005, Nature Medicine.

[28]  G. Hart,et al.  O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[29]  C. Cotman,et al.  Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. , 2004, The Journal of clinical investigation.

[30]  D. Bennett,et al.  Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. , 2004, Archives of neurology.

[31]  Akihiko Takashima,et al.  Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease , 2004, The Journal of Neuroscience.

[32]  Suzanne Craft,et al.  Insulin and neurodegenerative disease: shared and specific mechanisms , 2004, The Lancet Neurology.

[33]  G. Pasinetti,et al.  Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro. , 2003, Biochimica et biophysica acta.

[34]  R. Berry,et al.  Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[35]  L. Launer,et al.  Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. , 2002, Diabetes.

[36]  S. Fujita,et al.  Inhibition of Protein Phosphatase 2A Overrides Tau Protein Kinase I/Glycogen Synthase Kinase 3β and Cyclin-dependent Kinase 5 Inhibition and Results in Tau Hyperphosphorylation in the Hippocampus of Starved Mouse* , 2001, The Journal of Biological Chemistry.

[37]  I. Grundke‐Iqbal,et al.  Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[38]  V. Janssens,et al.  Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. , 2001, The Biochemical journal.

[39]  A Hofman,et al.  Diabetes mellitus and the risk of dementia , 1999, Neurology.

[40]  P. O'Brien,et al.  Risk of dementia among persons with diabetes mellitus: a population-based cohort study. , 1997, American journal of epidemiology.

[41]  M. Hasegawa,et al.  Sequential changes of tau-site-specific phosphorylation during development of paired helical filaments. , 1996, Dementia.

[42]  R. Kilgour,et al.  Effects of diabetes and food deprivation on shivering activity during progressive hypothermia in the rat. , 1996, Comparative biochemistry and physiology. Part A, Physiology.

[43]  Bradley T. Hyman,et al.  Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease , 1992, Neurology.

[44]  A. Delacourte,et al.  Pathological proteins Tau 64 and 69 are specifically expressed in the somatodendritic domain of the degenerating cortical neurons during Alzheimer's disease , 1990, Acta Neuropathologica.

[45]  I. Macdonald,et al.  Diabetes mellitus and thermoregulation. , 1987, Canadian journal of physiology and pharmacology.

[46]  H. Neil,et al.  Risk of hypothermia in elderly patients with diabetes. , 1986, British medical journal.

[47]  H. Wiśniewski,et al.  Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[48]  A. Frankfurter,et al.  The distribution of tau in the mammalian central nervous system , 1985, The Journal of cell biology.

[49]  G. Glenner,et al.  Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein , 1984 .

[50]  P. Trayhurn.  Thermoregulation in the diabetic-obese (db/db) mouse , 1979, Pflügers Archiv.

[51]  B. Hellman,et al.  Development of the insulin secretory defect in genetically diabetic (db/db) mouse. , 1978, Acta endocrinologica.

[52]  K P Hummel,et al.  Diabetes, a New Mutafton in the Mouse , 1966, Science.

[53]  B. W. Foster.  The Temperature in Diabetes. , 1869, Journal of anatomy and physiology.

[54]  A. Bretteville,et al.  Tau aggregates: toxic, inert, or protective species? , 2008, Journal of Alzheimer's disease : JAD.

[55]  D. Bennett,et al.  Biochemical Characterization of Aβ and Tau Pathologies in Mild Cognitive Impairment and Alzheimer's Disease , 2007 .

[56]  E. Mandelkow,et al.  Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro. , 2005, Methods in molecular biology.

[57]  M. Yousef,et al.  Thermoregulatory responses of diabetic rats. , 1989, Comparative biochemistry and physiology. A, Comparative physiology.