Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

[1]  Sean R. Davis,et al.  NCBI GEO: archive for functional genomics data sets—update , 2012, Nucleic Acids Res..

[2]  A. Børresen-Dale,et al.  Mutational Processes Molding the Genomes of 21 Breast Cancers , 2012, Cell.

[3]  Chunaram Choudhary,et al.  Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response. , 2012, Molecular cell.

[4]  Frédérick A. Mallette,et al.  RNF8‐ and RNF168‐dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites , 2012, The EMBO journal.

[5]  Joshua F. McMichael,et al.  Clonal evolution in relapsed acute myeloid leukemia revealed by whole genome sequencing , 2011, Nature.

[6]  E. Giné,et al.  Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia , 2011, Nature Genetics.

[7]  S. Sugano,et al.  Frequent pathway mutations of splicing machinery in myelodysplasia , 2011, Nature.

[8]  S. McDade,et al.  Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis , 2011, Nucleic acids research.

[9]  P. Hamilton,et al.  PARP inhibition induces BAX/BAK‐independent synthetic lethality of BRCA1‐deficient non‐small cell lung cancer , 2011, The Journal of pathology.

[10]  L. Corcos,et al.  Cotranscriptional exon skipping in the genotoxic stress response , 2010, Nature Structural &Molecular Biology.

[11]  J. Cerhan,et al.  Germline Variation in Apoptosis Pathway Genes and Risk of Non–Hodgkin's Lymphoma , 2010, Cancer Epidemiology, Biomarkers & Prevention.

[12]  Manuel de la Mata,et al.  DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation , 2009, Cell.

[13]  M. Post,et al.  Essential role for Bclaf1 in lung development and immune system function , 2009, Cell Death and Differentiation.

[14]  C. Bracken,et al.  Regulation of cyclin D1 RNA stability by SNIP1. , 2008, Cancer research.

[15]  S A Forbes,et al.  The Catalogue of Somatic Mutations in Cancer (COSMIC) , 2008, Current protocols in human genetics.

[16]  Henning Urlaub,et al.  Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. , 2006, RNA.

[17]  M. Durante,et al.  Measurements of metaphase and interphase chromosome aberrations transmitted through early cell replication rounds in human lymphocytes exposed to low-LET protons and high-LET 12C ions. , 2006, Mutation research.

[18]  M. Yaffe,et al.  MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks , 2005, Cell.

[19]  J. Manley,et al.  BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II. , 2005, Genes & development.

[20]  Francisco Martinez-Murillo,et al.  Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise , 2004, Nature Genetics.

[21]  J. Parvin,et al.  Redistribution of BRCA1 among Four Different Protein Complexes following Replication Blockage* , 2001, The Journal of Biological Chemistry.

[22]  S. Elledge,et al.  Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. , 1999, Science.

[23]  A. Krainer,et al.  Role of the Modular Domains of SR Proteins in Subnuclear Localization and Alternative Splicing Specificity , 1997, The Journal of cell biology.

[24]  D. Ganem,et al.  Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs , 2009, Nature Genetics.

[25]  K. Savage,et al.  BRCA1 and BRCA2: Role in the DNA Damage Response, Cancer Formation and Treatment , 2009 .

[26]  Y. Miki,et al.  Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. , 2007, Molecular and cellular biology.

[27]  J. Haveman,et al.  Clonogenic assay of cells in vitro , 2006, Nature Protocols.

[28]  A. Hollestelle,et al.  BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants. , 2006, Cancer research.

[29]  Ming K. Lee,et al.  22 genes from chromosome 17q21: cloning, sequencing, and characterization of mutations in breast cancer families and tumors. , 1995, Genomics.