Direct conversion of human fibroblasts to multilineage blood progenitors

[1]  Thomas Vierbuchen,et al.  Direct conversion of fibroblasts to functional neurons by defined factors , 2010, Nature.

[2]  Masaki Ieda,et al.  Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. , 2010, Cell.

[3]  Sheng Ding,et al.  A chemical platform for improved induction of human iPSCs , 2009, Nature Methods.

[4]  G. Daley,et al.  Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells , 2009, Nature Biotechnology.

[5]  A. Shakya,et al.  Stem cells, stress, metabolism and cancer: a drama in two Octs. , 2009, Trends in biochemical sciences.

[6]  Marcos J. Araúzo-Bravo,et al.  Direct reprogramming of human neural stem cells by OCT4 , 2009, Nature.

[7]  W. Fried,et al.  Erythropoietin and erythropoiesis. , 2009, Experimental hematology.

[8]  W. Vainchenker,et al.  A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis. , 2009, Blood.

[9]  R. Moon,et al.  Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells. , 2009, Cell stem cell.

[10]  J. Henderson,et al.  Genomic analysis of induced pluripotent stem (iPS) cells: routes to reprogramming , 2009, BioEssays : news and reviews in molecular, cellular and developmental biology.

[11]  Gideon Rechavi,et al.  Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient , 2009, PLoS medicine.

[12]  Mike J. Mason,et al.  Role of the Murine Reprogramming Factors in the Induction of Pluripotency , 2009, Cell.

[13]  T. Mikkelsen,et al.  Dissecting direct reprogramming through integrative genomic analysis , 2008, Nature.

[14]  T. Graf,et al.  PU.1 and C/EBPα/β convert fibroblasts into macrophage-like cells , 2008, Proceedings of the National Academy of Sciences.

[15]  R. Young,et al.  Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming , 2008, Cell.

[16]  K. Takatsu,et al.  Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells , 2008, The Journal of experimental medicine.

[17]  B. Thiers Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2008 .

[18]  Shulan Tian,et al.  Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.

[19]  S. Tapscott,et al.  p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation , 2007, Nature Structural &Molecular Biology.

[20]  T. Graf Faculty Opinions recommendation of Induction of pluripotent stem cells from adult human fibroblasts by defined factors. , 2007 .

[21]  A. Friedman Transcriptional control of granulocyte and monocyte development , 2007, Oncogene.

[22]  R. Lebofsky,et al.  New Myc-anisms for DNA replication and tumorigenesis? , 2007, Cancer cell.

[23]  M. Beal,et al.  Functional engraftment of human ES cell–derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes , 2006, Nature Medicine.

[24]  Angelique M. Nelson,et al.  Definitive-like erythroid cells derived from human embryonic stem cells coexpress high levels of embryonic and fetal globins with little or no adult globin. , 2006, Blood.

[25]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[26]  R. Wells,et al.  Differential lineage-specific regulation of murine CD45 transcription by Oct-1 and PU.1. , 2006, Biochemical and biophysical research communications.

[27]  G. Ehninger,et al.  Graft clonogenicity and intensity of pre-treatment: factors affecting outcome of autologous peripheral hematopoietic cell transplantation in patients with acute myeloid leukemia in first remission , 2005, Bone Marrow Transplantation.

[28]  Megan F. Cole,et al.  Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.

[29]  P. Robson,et al.  Transcriptional Regulation of Nanog by OCT4 and SOX2* , 2005, Journal of Biological Chemistry.

[30]  F. Rosenbauer,et al.  Role of Transcription Factors C/EBPα and PU.1 in Normal Hematopoiesis and Leukemia , 2005, International journal of hematology.

[31]  E. Stanley,et al.  The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells , 2005, Development.

[32]  J. Dick,et al.  Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity , 2004, Nature Immunology.

[33]  S. Ogawa,et al.  Runx1/AML-1 Ranks as a Master Regulator of Adult Hematopoiesis , 2004, Cell cycle.

[34]  P. Feugier,et al.  Hematologic recovery after autologous PBPC transplantation: importance of the number of postthaw CD34+ cells , 2003, Transfusion.

[35]  T. Wirth,et al.  B Cell–specific Transgenic Expression of Bcl2 Rescues Early B Lymphopoiesis but Not B Cell Responses in BOB.1/OBF.1-deficient Mice , 2003, The Journal of experimental medicine.

[36]  Stuart H. Orkin,et al.  Hematopoiesis and stem cells: plasticity versus developmental heterogeneity , 2002, Nature Immunology.

[37]  G. Daley,et al.  Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential. , 2001, Development.

[38]  C. Li,et al.  Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[39]  G. Lipowsky,et al.  CRISP-3, a protein with homology to plant defense proteins, is expressed in mouse B cells under the control of Oct2 , 1996, Molecular and cellular biology.

[40]  W. Vainchenker,et al.  Characterization of a bipotent erythro-megakaryocytic progenitor in human bone marrow. , 1996, Blood.

[41]  Y. Bernstein,et al.  Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[42]  H. Hassan,et al.  Stem cell factor as a survival and growth factor in human normal and malignant hematopoiesis. , 1996, Acta haematologica.

[43]  B. Kistler,et al.  Lymphoid- and myeloid-specific activity of the PU.1 promoter is determined by the combinatorial action of octamer and ets transcription factors. , 1995, Oncogene.

[44]  S. Orkin,et al.  Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL , 1995, Nature.

[45]  Stuart H. Orkin,et al.  An early haematopoietic defect in mice lacking the transcription factor GATA-2 , 1994, Nature.

[46]  T. Farrah,et al.  Molecular cloning of a ligand for the flt3 flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells , 1993, Cell.

[47]  W. Sly,et al.  Cloning, sequencing, and expression of cDNA for human beta-glucuronidase. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[48]  Mary Anne Wheeler,et al.  Stem , 1985 .