Cell penetrating peptides: overview and applications to the delivery of oligonucleotides
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[1] H. Moulton,et al. A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice. , 2009, Human molecular genetics.
[2] I. Graham,et al. Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study , 2009, The Lancet Neurology.
[3] Jean-Luc Coll,et al. Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth , 2009, Nucleic acids research.
[4] R. Juliano,et al. Biological barriers to therapy with antisense and siRNA oligonucleotides. , 2009, Molecular pharmaceutics.
[5] P. Lundin,et al. A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[6] M. C. Cardoso,et al. Cell Entry of Arginine-rich Peptides Is Independent of Endocytosis*S⃞ , 2009, Journal of Biological Chemistry.
[7] F. Edenhofer. Protein transduction revisited: novel insights into the mechanism underlying intracellular delivery of proteins. , 2008, Current pharmaceutical design.
[8] Noriyasu Kamei,et al. Usefulness of cell-penetrating peptides to improve intestinal insulin absorption. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[9] B. Lebleu,et al. Improved cell-penetrating peptide–PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle , 2008, Nucleic acids research.
[10] P. Iversen,et al. Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer , 2008, Proceedings of the National Academy of Sciences.
[11] P. Iversen,et al. Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure–activity studies , 2008, Nucleic acids research.
[12] H. Moulton,et al. Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function , 2008, Human molecular genetics.
[13] P. Iversen,et al. Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.
[14] C. Contag,et al. Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters , 2008, Proceedings of the National Academy of Sciences.
[15] Ralph Weissleder,et al. Multifunctional magnetic nanoparticles for targeted imaging and therapy. , 2008, Advanced drug delivery reviews.
[16] B. Cornelissen,et al. Cell penetrating peptides for in vivo molecular imaging applications. , 2008, Current pharmaceutical design.
[17] T. Restle,et al. Recent Developments in Peptide-Based Nucleic Acid Delivery , 2008, International journal of molecular sciences.
[18] M. Morris,et al. Cell‐penetrating peptides: from molecular mechanisms to therapeutics , 2008, Biology of the cell.
[19] P. Iversen,et al. Arginine‐rich cell penetrating peptides: Design, structure–activity, and applications to alter pre‐mRNA splicing by steric‐block oligonucleotides , 2008, Journal of peptide science : an official publication of the European Peptide Society.
[20] Vladimir P Torchilin,et al. Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers. , 2008, Advanced drug delivery reviews.
[21] P. Wender,et al. The design of guanidinium-rich transporters and their internalization mechanisms. , 2008, Advanced drug delivery reviews.
[22] A. Prochiantz,et al. Homeoproteins as natural Penetratin cargoes with signaling properties. , 2008, Advanced drug delivery reviews.
[23] S. Ohta,et al. PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes. , 2008, Advanced drug delivery reviews.
[24] Johan T den Dunnen,et al. Local dystrophin restoration with antisense oligonucleotide PRO051. , 2007, The New England journal of medicine.
[25] D. A. Stein,et al. Cell penetrating peptide conjugates of steric block oligonucleotides☆ , 2007, Advanced Drug Delivery Reviews.
[26] G. van Ommen,et al. Antisense-mediated exon skipping: a versatile tool with therapeutic and research applications. , 2007, RNA.
[27] P. Iversen,et al. Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.
[28] L. Chen,et al. Cell-penetrating peptides in drug development: enabling intracellular targets. , 2007, Biochemical Society transactions.
[29] Rainer Fischer,et al. A Comprehensive Model for the Cellular Uptake of Cationic Cell‐penetrating Peptides , 2007, Traffic.
[30] B. Lebleu,et al. Efficient splicing correction by PNA conjugation to an R6-Penetratin delivery peptide , 2007, Nucleic acids research.
[31] A. Prochiantz,et al. The topological role of homeoproteins in the developing central nervous system , 2007, Trends in Neurosciences.
[32] You Han Bae,et al. TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[33] D. A. Stein,et al. Antiviral Effects of Antisense Morpholino Oligomers in Murine Coronavirus Infection Models , 2007, Journal of Virology.
[34] M. Rezaee,et al. Impaired perfusion after myocardial infarction is due to reperfusion-induced deltaPKC-mediated myocardial damage. , 2007, Cardiovascular research.
[35] S. Donnini,et al. TAT‐BH4 counteracts Aβ toxicity on capillary endothelium , 2007 .
[36] P. Iversen,et al. Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[37] S. Dowdy,et al. Influence of protein transduction domains on intracellular delivery of macromolecules , 2006, Expert opinion on drug delivery.
[38] J. Rothbard,et al. Molecular Transporters: Synthesis of Oligoguanidinium Transporters and Their Application to Drug Delivery and Real‐Time Imaging , 2006, Chembiochem : a European journal of chemical biology.
[39] E. Hovig,et al. Photochemically induced gene silencing using PNA-peptide conjugates. , 2006, Oligonucleotides.
[40] Alain Thierry,et al. Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[41] P. Nielsen,et al. Photochemically enhanced cellular delivery of cell penetrating peptide‐PNA conjugates , 2006, FEBS letters.
[42] S. Wilton,et al. Dystrophin expression in the mdx mouse after localised and systemic administration of a morpholino antisense oligonucleotide , 2006, The journal of gene medicine.
[43] A. Rabinowitz,et al. Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology , 2006, Nature Medicine.
[44] B. Lebleu,et al. Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells , 2005, Nucleic acids research.
[45] Jesus M de la Fuente,et al. Tat peptide as an efficient molecule to translocate gold nanoparticles into the cell nucleus. , 2005, Bioconjugate chemistry.
[46] P. Nielsen,et al. Calcium ions effectively enhance the effect of antisense peptide nucleic acids conjugated to cationic tat and oligoarginine peptides. , 2005, Chemistry & biology.
[47] B. Lebleu,et al. Cellular Uptake of Unconjugated TAT Peptide Involves Clathrin-dependent Endocytosis and Heparan Sulfate Receptors* , 2005, Journal of Biological Chemistry.
[48] Steven F Dowdy,et al. Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer. , 2005, Advanced drug delivery reviews.
[49] Steven F Dowdy,et al. Cationic TAT peptide transduction domain enters cells by macropinocytosis. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[50] A. Rabinowitz,et al. Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[51] Roger Y Tsien,et al. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[52] W. Jiskoot,et al. OVCAR-3 cells internalize TAT-peptide modified liposomes by endocytosis. , 2004, Biochimica et biophysica acta.
[53] Joseph Rosenecker,et al. Application of Novel Solid Lipid Nanoparticle (SLN)-Gene Vector Formulations Based on a Dimeric HIV-1 TAT-Peptide in Vitro and in Vivo , 2004, Pharmaceutical Research.
[54] G. Steinberg,et al. Protein Kinase C δ Mediates Cerebral Reperfusion Injury In Vivo , 2004, The Journal of Neuroscience.
[55] M. Giacca,et al. Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins. , 2004, The Journal of biological chemistry.
[56] F. Rayne,et al. HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses. , 2004, Molecular biology of the cell.
[57] Steven F Dowdy,et al. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis , 2004, Nature Medicine.
[58] S. Gellman,et al. Cytoplasmic and Nuclear Delivery of a TAT-derived Peptide and a β-Peptide after Endocytic Uptake into HeLa Cells* , 2003, Journal of Biological Chemistry.
[59] Kurt Ballmer-Hofer,et al. Antennapedia and HIV Transactivator of Transcription (TAT) “Protein Transduction Domains” Promote Endocytosis of High Molecular Weight Cargo upon Binding to Cell Surface Glycosaminoglycans* , 2003, Journal of Biological Chemistry.
[60] Michael G. Yang,et al. Arginine-based molecular transporters: the synthesis and chemical evaluation of releasable taxol-transporter conjugates. , 2003, Organic letters.
[61] V. Torchilin,et al. TAT-liposomes: a novel intracellular drug carrier. , 2003, Current protein & peptide science.
[62] J. Mottram,et al. Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein. , 2002, The Biochemical journal.
[63] Y. Tseng,et al. Translocation of liposomes into cancer cells by cell-penetrating peptides penetratin and tat: a kinetic and efficacy study. , 2002, Molecular pharmacology.
[64] B. L. Wylie,et al. Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. , 2002, Journal of medicinal chemistry.
[65] M. Johansson,et al. Positively charged DNA-binding proteins cause apparent cell membrane translocation. , 2002, Biochemical and biophysical research communications.
[66] T. Bártfai,et al. Cargo delivery kinetics of cell-penetrating peptides. , 2001, Biochimica et biophysica acta.
[67] M. Manoharan,et al. Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs. , 2001, Nucleic acids research.
[68] H. Inokuchi,et al. Protein Transduction Domain of HIV-1 Tat Protein Promotes Efficient Delivery of DNA into Mammalian Cells* , 2001, The Journal of Biological Chemistry.
[69] V. Torchilin,et al. TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[70] E. Snyder,et al. Protein/peptide transduction domains: potential to deliver large DNA molecules into cells. , 2001, Current opinion in molecular therapeutics.
[71] D. Mukhopadhyay,et al. The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion. , 2001, Cancer research.
[72] G. Drin,et al. Physico-chemical requirements for cellular uptake of pAntp peptide. Role of lipid-binding affinity. , 2001, European journal of biochemistry.
[73] R. Brasseur,et al. Translocation of the pAntp peptide and its amphipathic analogue AP-2AL. , 2001, Biochemistry.
[74] C. Mann,et al. Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[75] J. Rothbard,et al. Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation , 2000, Nature Medicine.
[76] J. Rothbard,et al. Polyarginine enters cells more efficiently than other polycationic homopolymers. , 2000, The journal of peptide research : official journal of the American Peptide Society.
[77] D. Piwnica-Worms,et al. Novel Tat-peptide chelates for direct transduction of technetium-99m and rhenium into human cells for imaging and radiotherapy. , 2000, Bioconjugate chemistry.
[78] R Weissleder,et al. Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide. , 2000, Bioconjugate chemistry.
[79] S. Schwarze,et al. In vivo protein transduction: delivery of a biologically active protein into the mouse. , 1999, Science.
[80] R Weissleder,et al. High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates. , 1999, Bioconjugate chemistry.
[81] B. Wiesner,et al. Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically. , 1998, Biochimica et biophysica acta.
[82] T. Hökfelt,et al. Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo , 1998, Nature Biotechnology.
[83] M. Manoharan,et al. Modification of splicing in the dystrophin gene in cultured Mdx muscle cells by antisense oligoribonucleotides. , 1998, Human molecular genetics.
[84] R. Kole,et al. Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development. , 1998, Biochemistry.
[85] C. Granier,et al. Structure-activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1 Tat protein , 1997, Letters in Peptide Science.
[86] L. Chaloin,et al. A new peptide vector for efficient delivery of oligonucleotides into mammalian cells. , 1997, Nucleic acids research.
[87] Priscille Brodin,et al. A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus* , 1997, The Journal of Biological Chemistry.
[88] M. Hasegawa,et al. Identification of a binding region onEscherichia coli heat-stable enterotoxin to intestinal guanylyl cyclase C , 1997, Letters in Peptide Science.
[89] A. Prochiantz,et al. The third helix of the Antennapedia homeodomain translocates through biological membranes. , 1994, The Journal of biological chemistry.
[90] J Barsoum,et al. Tat-mediated delivery of heterologous proteins into cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[91] A. Prochiantz,et al. alpha-2,8-Polysialic acid is the neuronal surface receptor of antennapedia homeobox peptide. , 1991, The New biologist.
[92] Carl O. Pabo,et al. Cellular uptake of the tat protein from human immunodeficiency virus , 1988, Cell.
[93] Vladimir P Torchilin,et al. Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery. , 2008, Biopolymers.
[94] Hans P Merkle,et al. On the biomedical promise of cell penetrating peptides: limits versus prospects. , 2008, Journal of pharmaceutical sciences.
[95] S. Donnini,et al. TAT-BH4 counteracts Abeta toxicity on capillary endothelium. , 2007, FEBS letters.
[96] Y. Tsujimoto,et al. BH4 peptide derivative from Bcl-xL attenuates ischemia/reperfusion injury thorough anti-apoptotic mechanism in rat hearts. , 2005, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
[97] G. Steinberg,et al. Protein kinase C delta mediates cerebral reperfusion injury in vivo. , 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[98] E. Vivés,et al. Structure–activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1 Tat protein , 2004, Letters in Peptide Science.
[99] E. Vivés,et al. Cell-penetrating Peptides A REEVALUATION OF THE MECHANISM OF CELLULAR UPTAKE* , 2002 .
[100] M. Pooga,et al. Cell penetration by transportan. , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.