Hsp70-Bim interaction facilitates mitophagy by recruiting parkin and TOMM20 into a complex
暂无分享,去创建一个
Hong Zhang | Zhichao Zhang | T. Song | Ziqian Wang | Yafei Guo | Fangkui Yin | Yao Tang | Peng Liu
[1] Yan Guan,et al. Mitophagy in carcinogenesis, drug resistance and anticancer therapeutics , 2021, Cancer cell international.
[2] Hong Zhang,et al. Bim transfer between Bcl-2-like protein and Hsp70 underlines Bcl-2/Hsp70 crosstalk to regulate apoptosis. , 2021, Biochemical pharmacology.
[3] Hong Zhang,et al. Small-molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance , 2021, Leukemia.
[4] Hong Zhang,et al. A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction. , 2021, European journal of medicinal chemistry.
[5] Yingang Feng,et al. The chaperone Hsp70 is a BH3 receptor activated by the pro-apoptotic Bim to stabilize anti-apoptotic clients , 2020, The Journal of Biological Chemistry.
[6] M. La Noce,et al. The role of autophagy in resistance to targeted therapies. , 2020, Cancer treatment reviews.
[7] P. Agostinis,et al. Mitophagy in Cancer: A Tale of Adaptation , 2019, Cells.
[8] Yingyu Chen,et al. AMPK and Autophagy. , 2019, Advances in experimental medicine and biology.
[9] A. Birbrair,et al. Mitophagy-driven metabolic switch reprograms stem cell fate , 2018, Cellular and Molecular Life Sciences.
[10] Heng Wu,et al. Mitochonic acid 5 activates the MAPK–ERK–yap signaling pathways to protect mouse microglial BV-2 cells against TNFα-induced apoptosis via increased Bnip3-related mitophagy , 2018, Cellular & Molecular Biology Letters.
[11] C. K. Das,et al. Pro-survival autophagy and cancer cell resistance to therapy , 2018, Cancer and Metastasis Reviews.
[12] B. Tang,et al. Hsp70 participates in PINK1-mediated mitophagy by regulating the stability of PINK1 , 2018, Neuroscience Letters.
[13] D. McConkey. The integrated stress response and proteotoxicity in cancer therapy. , 2017, Biochemical and biophysical research communications.
[14] L. Ye,et al. p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation , 2016, Cellular & Molecular Biology Letters.
[15] P. Matarrese,et al. Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation , 2016, Autophagy.
[16] Mason R. Mackey,et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress , 2015, Proceedings of the National Academy of Sciences.
[17] N. Chandel,et al. Jnk2 promotes stress-induced mitophagy and suppresses inflammasome activation by targeting smARF for degradation , 2015, Nature Immunology.
[18] Y. Kitagishi,et al. Functions and characteristics of PINK1 and Parkin in cancer. , 2015, Frontiers in bioscience.
[19] J. Wells,et al. Small-molecule inhibitors of protein-protein interactions: progressing toward the reality. , 2014, Chemistry & biology.
[20] S. Cullen,et al. Bcl-2 family proteins participate in mitochondrial quality control by regulating Parkin/PINK1-dependent mitophagy. , 2014, Molecular cell.
[21] D. Vaux,et al. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak , 2014, Proceedings of the National Academy of Sciences.
[22] Scott E. Martin,et al. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy , 2013, Nature.
[23] T. Pandita,et al. Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy , 2013, Proceedings of the National Academy of Sciences.
[24] G. Kroemer,et al. Molecular mechanisms of selective autophagy , 2012, Cell Death and Differentiation.
[25] C. Rudin,et al. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer , 2013, Molecular Cancer.
[26] Ye Xu,et al. The BH3 mimetic S1 induces autophagy through ER stress and disruption of Bcl-2/Beclin 1 interaction in human glioma U251 cells. , 2012, Cancer letters.
[27] D. Rubinsztein,et al. Bim Inhibits Autophagy by Recruiting Beclin 1 to Microtubules , 2012, Molecular cell.
[28] A. Thorburn,et al. Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy , 2012, Autophagy.
[29] Zhichao Zhang,et al. A novel BH3 mimetic S1 potently induces Bax/Bak‐dependent apoptosis by targeting both Bcl‐2 and Mcl‐1 , 2011, International journal of cancer.
[30] Zhichao Zhang,et al. 3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile (S1) based molecules as potent, dual inhibitors of B-cell lymphoma 2 (Bcl-2) and myeloid cell leukemia sequence 1 (Mcl-1): structure-based design and structure-activity relationship studies. , 2011, Journal of medicinal chemistry.
[31] D. Klionsky,et al. Regulation mechanisms and signaling pathways of autophagy. , 2009, Annual review of genetics.
[32] Osamu Takeuchi,et al. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. , 2009, Molecular cell.
[33] G. Kroemer,et al. Bcl-2 family members: Dual regulators of apoptosis and autophagy , 2008, Autophagy.
[34] J. Vicencio,et al. BH3-Only Proteins and BH3 Mimetics Induce Autophagy by Competitively Disrupting the Interaction between Beclin 1 and Bcl-2/Bcl-XL , 2007, Autophagy.
[35] D. Hardie,et al. Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes , 2006, The Journal of experimental medicine.
[36] N. Mizushima. The pleiotropic role of autophagy: from protein metabolism to bactericide , 2005, Cell Death and Differentiation.