Effect of aqueous extract of Eugenia caryophyllus on brain acetylcholine esterase in rats.

The effect of aqueous extract of Eugenia caryophyllus on brain acetylcholine esterase (AChE) activity in rats was studied. Results indicate that the aqueous extract reduced the hydrolysis of acetylcholine (ACh) by AChE. This reducing effect was not due to the acidic nature of the extract and suggests that Eugenia caryophyllus contains some water soluble substance(s) with anti-choline esterase activity.