Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys

[1]  W. Aoi Characteristics of Skeletal Muscle as a Secretory Organ , 2017 .

[2]  Xiao-ming Meng,et al.  TGF-β: the master regulator of fibrosis , 2016, Nature Reviews Nephrology.

[3]  B. Spiegelman,et al.  PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer. , 2016, Cell metabolism.

[4]  M. Bhasin,et al.  PGC1α-dependent NAD biosynthesis links oxidative metabolism to renal protection , 2016, Nature.

[5]  W. Mitch,et al.  CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation. , 2016, Journal of the American Society of Nephrology : JASN.

[6]  Youhua Liu,et al.  Renal fibrosis in 2015: Understanding the mechanisms of kidney fibrosis , 2016, Nature Reviews Nephrology.

[7]  C. Handschin,et al.  Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise. , 2015, Bone.

[8]  W. Mitch,et al.  JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis. , 2015, Journal of the American Society of Nephrology : JASN.

[9]  L. Truong,et al.  Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy , 2015, The Journal of pathology.

[10]  X. Sui,et al.  Exercise capacity and risk of chronic kidney disease in US veterans: a cohort study. , 2015, Mayo Clinic proceedings.

[11]  S. Allison Fibrosis: Dysfunctional fatty acid oxidation in renal fibrosis , 2015, Nature Reviews Nephrology.

[12]  Kumar Sharma,et al.  Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development , 2014, Nature Medicine.

[13]  M. Okano,et al.  Cohort Study , 2020, Definitions.

[14]  P. D. De Jager,et al.  Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes. , 2014, Journal of the American Society of Nephrology : JASN.

[15]  Ina Schuppe-Koistinen,et al.  Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression , 2014, Cell.

[16]  R. Zager,et al.  Renal cortical pyruvate depletion during AKI. , 2014, Journal of the American Society of Nephrology : JASN.

[17]  Yuan Zhang,et al.  Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling , 2014, Diabetes.

[18]  M. Febbraio,et al.  Muscles, exercise and obesity: skeletal muscle as a secretory organ , 2012, Nature Reviews Endocrinology.

[19]  B. Spiegelman,et al.  A PGC1α-dependent myokine that drives browning of white fat and thermogenesis , 2012, Nature.

[20]  Shingo,et al.  A PGC1-\(\alpha\)-dependent Myokine that Drives Brown-fat-like Development of White Fat and Thermogenesis , 2012 .

[21]  R. Robey Hexokinase: a novel sugar kinase coupled to renal epithelial cell survival. , 2011, Kidney international.

[22]  Steven P Jones,et al.  Bioenergetic function in cardiovascular cells: the importance of the reserve capacity and its biological regulation. , 2011, Chemico-biological interactions.

[23]  Wei Li,et al.  TβRI/Alk5-independent TβRII signaling to ERK1/2 in human skin cells according to distinct levels of TβRII expression , 2011, Journal of Cell Science.

[24]  R. Star,et al.  Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model. , 2010, Kidney international.

[25]  T. Clemens,et al.  TGF-β type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling , 2010, Nature Cell Biology.

[26]  Qianqian Wang,et al.  Single-molecule imaging reveals transforming growth factor-β-induced type II receptor dimerization , 2009, Proceedings of the National Academy of Sciences.

[27]  R. Foley,et al.  Prevalence of CKD in the United States: a sensitivity analysis using the National Health and Nutrition Examination Survey (NHANES) 1999-2004. , 2009, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[28]  Christoph Handschin,et al.  The role of exercise and PGC1α in inflammation and chronic disease , 2008, Nature.

[29]  Christoph Handschin,et al.  The Role of Exercise and Pgc1alpha in Inflammation and Chronic Disease , 2022 .

[30]  D. Nicholls,et al.  Spare Respiratory Capacity Rather Than Oxidative Stress Regulates Glutamate Excitotoxicity after Partial Respiratory Inhibition of Mitochondrial Complex I with Rotenone , 2007, The Journal of Neuroscience.

[31]  Kebin Hu,et al.  hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists. , 2006, Journal of the American Society of Nephrology : JASN.

[32]  Kebin Hu,et al.  Hepatocyte Growth Factor Is a Downstream Effector that Mediates the Antifibrotic Action of Peroxisome Proliferator–Activated Receptor-γ Agonists , 2005 .

[33]  Charles E McCulloch,et al.  Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. , 2004, The New England journal of medicine.

[34]  Ying E. Zhang,et al.  Smad-dependent and Smad-independent pathways in TGF-β family signalling , 2003, Nature.

[35]  Li-jun Ma,et al.  Model of robust induction of glomerulosclerosis in mice: importance of genetic background. , 2003, Kidney international.

[36]  J. Massagué,et al.  Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus , 2003, Cell.

[37]  J. Massagué,et al.  Mechanisms of TGF-beta signaling from cell membrane to the nucleus. , 2003, Cell.

[38]  R. Derynck,et al.  Smad-dependent and Smad-independent pathways in TGF-beta family signalling. , 2003, Nature.

[39]  L. Nolte,et al.  Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1 , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[40]  Jiandie D. Lin,et al.  Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres , 2002, Nature.

[41]  Jiandie D. Lin,et al.  Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. , 2002, Nature.

[42]  Hong-Jian Zhu,et al.  A Pivotal Role for the Transmembrane Domain in Transforming Growth Factor-β Receptor Activation* , 1999, The Journal of Biological Chemistry.

[43]  K. Nath The tubulointerstitium in progressive renal disease. , 1998, Kidney international.

[44]  A. S. Appel,et al.  Acute Renal Failure , 1960, Advances in Experimental Medicine and Biology.